Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 unless you have confirmed active herpes viruses, why not just take antiretrovirals for XMV? From: Penny Houle <pennyhoule@...>infection & Inflammation group <infections >Sent: Sat, July 24, 2010 10:36:20 AMSubject: [infections] Cimetidine/Tagament for Virus I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 Hi Penny /all , Good info on Cimetidine..Another mechanism is detailed below on how Cimitidine helps with a antibiotic damaged gut! http://www.yeast-candida-infections-uk.co.uk/treatment-of-autism-and-yeast-infections The information is of course not conclusive but it would support the general theory that our gut flora generally has been downgraded by the use of antibiotics leading to impaired synthesizing of vitamins leading to poor elimination of Xenobiotics [ biologically active chemical/metal which is found in an organism but which is not normally produced or expected to be present in it]. It can also cover substances which are present in much higher concentrations than are usual. Metals act as catalysts. The presence of metals in biological systems in an uncomplicated form can significantly increase the level of oxidative stress. Interlinked with Oxidative stress is a process called methylation which is involved in regulating many cellular processes and gene switching. under-methylators are about 45% of the "autism" population. Mercury toxicity may disrupt the methylation cycle making it practically unsolvable until the metals are removed. Several common supplements often recommended for those with autism spectrum conditions are involved in this process (this is just one of the processes Vitamins and mineral supplements may help with). Poor histamine clearance is a direct consequence of impaired Methylation. Histamine blockers [ H2 antagonists] have proved to be effective in treating cancer . Cimetidine is a common drug used as an antacid Cimetidine works by blocking H2 receptors . This site makes interesting readinghttp://www.second-opinions.co.uk/cimetidine.html ">“Is Cimetidine (Tagamet) a Better Cure for Cancer?” The main mechanism of lowering histamine is by an enzyme produced in the gut mucosa. So if you have an injured gut for whatever reason, less enzyme may be produced, and this may mean you have a lower ability to eliminate histamine. It’s known that many autistic children are contaminated with metals/pesticides, this has lead to a widespread belief that this could be the basic cause for the condition. The arguments against such a basic conclusion are simple, where are the children of just a few months old that have never been away from parental supervision acquiring these health destroying amounts of contaminants, And how do other children of the same age and living in the same environment avoid the said contaminants. The situation strengthens the argument that we need normal gut flora to metabolise metals pesticides etc; Without a pathway to excrete contaminants we all encounter daily they build up within the body .In a mouse study it was proved intestinal micro-flora is a major factor determining the excretion rate of mercury [see.. Yeast, Genes, Enzyme production, Metal toxicity ] Cancer is an infection .when cancer cells which we produce everyday as a normal situation fail to be gobbled up [phagocytised] by cells of our immune system. The main cells associated with this process [ Phagocytosis.] are called Macrophages they are multifunctional immune cells. just to make the point again- our gut flora is our immune system.. how to manipulate our gut flora is the key to good health Antiretroviral Drugs The following information comes from DR. ANDREW MANIOTIS, PhD Assistant Research Professor Program Director Cell and Development Biology of Cancer, Departments of Pathology and Bioengineering, University of Illinois, Chicago http://aras.ab.ca/articles/scientific/20071007-Maniotis-Lambros.pdf However, to my knowledge, there is no evidence that any antiretroviral drugs attack or interfere with any virus directly. In all likelihood, antiretrovirals modulate the immune system into either waking up, producing more antibodies or, in some cases -- in high-dose regimens, they actually kill bacteria, mycoplasmas, and fungi, that may be present in a immune suppressed patient. At higher doses or during long term usage, these drugs also modulate your cells, and eventually, kill the cells of the immune system and other organs. On 24/07/2010 15:36, Penny Houle wrote: I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals.org/content/99/3/410.2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. No virus found in this incoming message. Checked by AVG - www.avg.com Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 I think that's a hot topic of discussion, but I don't know many doctors who will start prescribing anti-virals without some kind of research to back it up. I brought up cimetidine as a potential anti-viral that's easy to get over the counter. Low dose naltrexone is another immune booster that some doctors are prescribing now. It needs to be made at a compounding pharmacy, but another therapy worth checking into. From: Sue <suebackagain123@...>Subject: Re: [infections] Cimetidine/Tagament for Virusinfections Date: Saturday, July 24, 2010, 11:11 PM unless you have confirmed active herpes viruses, why not just take antiretrovirals for XMV? From: Penny Houle <pennyhoule (DOT) com>infection & Inflammation group <InfectionAndInflamm ation2@grou ps.com>Sent: Sat, July 24, 2010 10:36:20 AMSubject: [infectionAndInflam mation2] Cimetidine/Tagament for Virus I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 Weird story. You would think someone studies EBV or T_s cells and would be interested in his mono cure. I suspect that those who are lifelong specialists in something can get very irritated sometimes when a generalist makes a big discovery about their subject. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 Its just such a shame. Retroviral infections are so serious and damage begins early after infection (like 2 weeks or something). I can only wonder what will become of me, starting the meds 18 yrs later! I had hoped more doctors would take this seriously now. From: Penny Houle <pennyhoule@...>infections Sent: Sun, July 25, 2010 10:47:17 AMSubject: Re: [infections] Cimetidine/Tagament for Virus I think that's a hot topic of discussion, but I don't know many doctors who will start prescribing anti-virals without some kind of research to back it up. I brought up cimetidine as a potential anti-viral that's easy to get over the counter. Low dose naltrexone is another immune booster that some doctors are prescribing now. It needs to be made at a compounding pharmacy, but another therapy worth checking into. From: Sue <suebackagain123@ .ca>Subject: Re: [infectionAndInflam mation2] Cimetidine/Tagament for VirusInfectionAndInflamm ation2@grou ps.comDate: Saturday, July 24, 2010, 11:11 PM unless you have confirmed active herpes viruses, why not just take antiretrovirals for XMV? From: Penny Houle <pennyhoule (DOT) com>infection & Inflammation group <InfectionAndInflamm ation2@grou ps.com>Sent: Sat, July 24, 2010 10:36:20 AMSubject: [infectionAndInflam mation2] Cimetidine/Tagament for Virus I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 There's a thread discussing Tagamet/Cimetidine over at Phoenix Rising if that's any help to you at all. http://www.forums.aboutmecfs.org/showthread.php?2077-Tagamet-(cimetidine)-for-CFIDS-(worked-for-me) & highlight=Tagamet From: Penny Houle <pennyhoule@...>infections Sent: Sun, July 25, 2010 10:47:17 AMSubject: Re: [infections] Cimetidine/Tagament for Virus I think that's a hot topic of discussion, but I don't know many doctors who will start prescribing anti-virals without some kind of research to back it up. I brought up cimetidine as a potential anti-viral that's easy to get over the counter. Low dose naltrexone is another immune booster that some doctors are prescribing now. It needs to be made at a compounding pharmacy, but another therapy worth checking into. From: Sue <suebackagain123@ .ca>Subject: Re: [infectionAndInflam mation2] Cimetidine/Tagament for VirusInfectionAndInflamm ation2@grou ps.comDate: Saturday, July 24, 2010, 11:11 PM unless you have confirmed active herpes viruses, why not just take antiretrovirals for XMV? From: Penny Houle <pennyhoule (DOT) com>infection & Inflammation group <InfectionAndInflamm ation2@grou ps.com>Sent: Sat, July 24, 2010 10:36:20 AMSubject: [infectionAndInflam mation2] Cimetidine/Tagament for Virus I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 great post. Thanks, . I was reminded of cimetidine because my gut has been acting up the last few days. It's usually the one place in my body that seems pretty solid, but not so much the last few days. I've got heartburn too, and the cimetidine obviously helps with that. I know that you're right about a big part of the immune system being in the stomach. At least 60% if not more. I'm sure the years on abx have contributed to my gut changing. My body's balance has definitely become interdependent with the antibiotics. I've probably altered my dna. But trying to live without antibiotics is much worse than living with them. One of the worst things I did to screw up my gut after it had functioned so well for so long, was about a year ago when I take a big dose of flagyl. I don't know what I was thinking. Should have started small, but I took a double dose and ended up so violently sick that I'm afraid to even look at the stuff now. After that episode, my gut has been less stable with some ibs type symptoms that I had 20 plus years ago, although milder. But the more immediate cause of my current gut problems is probably due to a fungal overload as a result to succumbing to a ridiculous sweet tooth. First time in my life. The sugar is clearly having a negative effect on my gut. One thing I know will help is taking Chromium. Chromium has always killed my sugar/carb cravings very effectively (it's known to help diabetics with insulin regulation). I just have to go get some. When I've used it in the past, it has taken up to 2 weeks for the cravings to go away, but not only did they go away, I started craving protein, in particular chicken (which I normally find very boring), so I have no doubt that chromium can have a very big impact on sugar/carb cravings and insulin regulation. In the meantime, I'm going to keep taking the cimetidine and see if I notice any symptom improvements outside the indigestion and heartburn. Once I start the chromium to reduce the sugar/fungal issues, it will be easier to guage other effects of the chromium beyond the digestive. But if it's potentially therapeutic for cancer, and it's such a benign drug in general, I don't have a problem taking it as a preventative, even if it has no effect on my specific infection. I can't imagine how all those poor people with ulcers managed before Cimetidine came along (and the realization that ulcers are caused by bacteria). Being told to reduce stress and drink milk! Unbelievable! What suffering they must have had to endure. We used to hear of ulcers all the time as related to stress. Hardly ever do anymore. But the fact that a bacterial caused condition, like stomach ulcers, responded positively to Cimetidine, is another reason to give cimetidine type drugs another look. penny I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. No virus found in this incoming message. Checked by AVG - www.avg.com Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 Yeah, I know. I feel the same way, but the good news is that break-throughs may finally be gaining some steam, even if it's just in the medical establishment's way of thinking. Once they accept something as "true" they'll also have to stop treating us like "malingerers" or "head cases" and acknowledge that there is a medical basis for our symptoms and therapy is needed. I guess it would be better than nothing, to know that when you step into a doctor's exam room, that he's most likely taking you seriously. Or that your family, or ex's family, can no longer get away with saying "get over it". :-( So much ignorance! I just hope that these doctors also wake up soon to what bacterial infections are doing to people. It's unbelievable how many bizarre illnesses are out there caused by bacteria, like deafness and blindness and flesh being eaten away, and yet they refuse to acknowledge that bugs can cause an illness that slowly deteriorates one's immune system and robs one's health in the process. They know that bugs can mutate and that bio-films exist as an inpenetrable armor. Why can't they see that bio-films are the reason treatments aren't all that effective and infections come back, or why don't ENT's make the connection to why sinus surgery is rarely that successful? My sinuses are clearly so coated with that hardened slime that I get no relief from nasal migraine meds, but give me a shot of the same drug which goes directly into the blood stream and the migraine is gone in 3 minutes. And I am far from alone in that experience. Seems so obvious and yet doctors seem to be the last to make the connections. Okay, end of rant. I'm trying to stay positive that good things are going to come of these new discoveries. Like the old saying, "the only thing that never changes is change". Something's gotta give here, sooner than later. From: Sue <suebackagain123@ .ca>Subject: Re: [infectionAndInflam mation2] Cimetidine/Tagament for VirusInfectionAndInflamm ation2@grou ps.comDate: Saturday, July 24, 2010, 11:11 PM unless you have confirmed active herpes viruses, why not just take antiretrovirals for XMV? From: Penny Houle <pennyhoule (DOT) com>infection & Inflammation group <InfectionAndInflamm ation2@grou ps.com>Sent: Sat, July 24, 2010 10:36:20 AMSubject: [infectionAndInflam mation2] Cimetidine/Tagament for Virus I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 Thanks for the link. Definitely interesting. I think Goldstein said that perhaps only 20% of his cfs patients responded to cimetidine, so it could be a long shot, or it could just take time to recognize the benefits, or, if you end up cancer free, how would you know it wasn't because of cimetidine? Lots of interesting stuff. I've been finding Goldstein more and more interesting of late. I don't remember how much I posted about this, but my Neurologist has been giving me nerve blocks for my migraines. The crazy thing, is that blocking that nerve also had the unexpected side effects of joint pain disappearing, muscle weakness going away, energy increasing. Basically all of my symptoms improving greatly or disappearing entirely. I felt like a new person, just because of a nerve block. I kow that Goldstein worked primarily with brain chemistry, but it seems very clear to me, after having received these nerve blocks, that my body is getting mixed signals from my brain and is over reacting with all kinds of pain and fatigue issues. The bad news is the nerve blocks only last for 2 to 3 weeks, but the good news is there's another procedure which acts in the same way and lasts for 6 months or so. I'm going to give that a go. From: Sue <suebackagain123@ .ca>Subject: Re: [infectionAndInflam mation2] Cimetidine/Tagament for VirusInfectionAndInflamm ation2@grou ps.comDate: Saturday, July 24, 2010, 11:11 PM unless you have confirmed active herpes viruses, why not just take antiretrovirals for XMV? From: Penny Houle <pennyhoule (DOT) com>infection & Inflammation group <InfectionAndInflamm ation2@grou ps.com>Sent: Sat, July 24, 2010 10:36:20 AMSubject: [infectionAndInflam mation2] Cimetidine/Tagament for Virus I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2010 Report Share Posted July 25, 2010 Penny a sweet tooth is one of the symptoms of a yeast infection ..as treatment progresses the craving for sugar goes ..it happened with me ..On the subject of stimulating the immune system , We now know that our commensal gut flora have extraordinary abilities ..in the normal flora sect of my site I provide info that gut flora can manipulate the immune system actually eliciting an immune response then switching it off ..wow.. Now, with a gut dysbiosis gut flora are exported throughout the body ..bacteria that can manipulate the immune system... I believe that’s why we are chronically ill and why I provide info on stimulating the IS …It explains my improvement overall when suffering a cold ..anyway food for thought ..I presented my data to government scientists last week the presentation and discussion lasted 3 hours ,,a big success I’ll keep you all posted as and when things develop On 25/07/2010 16:42, Penny Houle wrote: great post. Thanks, . I was reminded of cimetidine because my gut has been acting up the last few days. It's usually the one place in my body that seems pretty solid, but not so much the last few days. I've got heartburn too, and the cimetidine obviously helps with that. I know that you're right about a big part of the immune system being in the stomach. At least 60% if not more. I'm sure the years on abx have contributed to my gut changing. My body's balance has definitely become interdependent with the antibiotics. I've probably altered my dna. But trying to live without antibiotics is much worse than living with them. One of the worst things I did to screw up my gut after it had functioned so well for so long, was about a year ago when I take a big dose of flagyl. I don't know what I was thinking. Should have started small, but I took a double dose and ended up so violently sick that I'm afraid to even look at the stuff now. After that episode, my gut has been less stable with some ibs type symptoms that I had 20 plus years ago, although milder. But the more immediate cause of my current gut problems is probably due to a fungal overload as a result to succumbing to a ridiculous sweet tooth. First time in my life. The sugar is clearly having a negative effect on my gut. One thing I know will help is taking Chromium. Chromium has always killed my sugar/carb cravings very effectively (it's known to help diabetics with insulin regulation). I just have to go get some. When I've used it in the past, it has taken up to 2 weeks for the cravings to go away, but not only did they go away, I started craving protein, in particular chicken (which I normally find very boring), so I have no doubt that chromium can have a very big impact on sugar/carb cravings and insulin regulation. In the meantime, I'm going to keep taking the cimetidine and see if I notice any symptom improvements outside the indigestion and heartburn. Once I start the chromium to reduce the sugar/fungal issues, it will be easier to guage other effects of the chromium beyond the digestive. But if it's potentially therapeutic for cancer, and it's such a benign drug in general, I don't have a problem taking it as a preventative, even if it has no effect on my specific infection. I can't imagine how all those poor people with ulcers managed before Cimetidine came along (and the realization that ulcers are caused by bacteria). Being told to reduce stress and drink milk! Unbelievable! What suffering they must have had to endure. We used to hear of ulcers all the time as related to stress. Hardly ever do anymore. But the fact that a bacterial caused condition, like stomach ulcers, responded positively to Cimetidine, is another reason to give cimetidine type drugs another look. penny I've talked about this before but thought it might be a good time to revisit Cimetidine (Tagament) as an anti-viral medication (a benign one at that). Dr. Jay Goldstein in Los Angeles reported that Cimetidine could cure the Mononuecleosis virus within 1 to 2 days. And he became so frustrated at the lack of attention to this finding that he more or less gave up trying to get people to listen. However, I recently was doing a search on "Cimetidine virus" and came across numerous claims from people who find it helps stop or slow their Herpes outbreaks. (apparently, mono is a type of herpes virus.) So with all the talk of the new XMRV retro-virus, it may be time to take another look at Cimetidine or other drugs that affect T-cells and their receptors. From ANNALS OF INTERNAL MEDICINE Cimetidine and Mononucleosis JAY A. GOLDSTEIN, M.D. Excerpt To the editor: For 2 years I have been treating patients in my family practice who have mononucleosis with cimetidine, 300 mg three times a day for 5 days. Twenty-nine of thirty-two patients have had almost complete remission of symptoms in 1 or 2 days, and in no patient has the disease recurred. There have been no adverse effects and no complications. Because herpes virus disorders may cause excessive suppressor T-cell activity (1) and because suppressor T cells have H-2 receptors, (2) this excessive activity may be partially blocked by cimetidine. Suppressor T cells may secrete lymphokines that may be... http://www.annals. org/content/ 99/3/410. 2.extract There are more excerpts out there if you do a search for Goldstein and Cimetidine. In some places he talks about a 20% success rate in his CFS patients. No virus found in this incoming message. Checked by AVG - www.avg.com Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 No virus found in this incoming message. Checked by AVG - www.avg.com Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2010 Report Share Posted August 15, 2010 Speaking of Ulcers- My hubby and I went to Mexico in Feb this year and I contracted h. pylori... or put it this way ( in case it was latent and just decided to show symptoms)... I became symptomatic about 10 days after returning. Waking up at night with a gnawing sensation in my gut- feeling sicj about 1 hr after eating.. etc. Quest diagnostics confirmed positive for h.pylori by blood test ( antibodies). I took a modified version of the PrevPac ( 1 G clarithromycin, 2G amoxicillin % 60 mg Nexium with 8 Oz Kefir and 500,000 cfu Nystatin) daily for 2 .5 weeks... then 6 weeks later tested Negative for H. Pylori antigen by Fecal Test. My guts been great since. I imagine that killed some Lyme if there was any unexposed as well!. Bonus. Barb > >> I've talked about this before but thought it might be a good time > >> to revisit Cimetidine (Tagament) as an anti-viral medication (a > >> benign one at that). > >> Dr. Jay Goldstein in Los Angeles reported that Cimetidine could > >> cure the Mononuecleosis virus within 1 to 2 days. And he became > >> so frustrated at the lack of attention to this finding that he > >> more or less gave up trying to get people to listen. > >> However, I recently was doing a search on " Cimetidine virus " and > >> came across numerous claims from people who find it helps stop or > >> slow their Herpes outbreaks. (apparently, mono is a type of > >> herpes virus.) > >> So with all the talk of the new XMRV retro-virus, it may be time > >> to take another look at Cimetidine or other drugs that affect > >> T-cells and their receptors. > >> *From ANNALS OF INTERNAL MEDICINE* > >> > >> > >> Cimetidine and Mononucleosis > >> > >> 1. JAY A. GOLDSTEIN > >> <http://www.annals.org/search?author1=JAY+A.+GOLDSTEIN & sortspec=date & submit=Subm\ it>, > >> M.D. > >> > >> *Excerpt* > >> > >> ** > >> > >> To the editor: For 2 years I have been treating patients in my > >> family practice who have mononucleosis with cimetidine, 300 mg > >> three times a day for 5 days. Twenty-nine of thirty-two patients > >> have had almost complete remission of symptoms in 1 or 2 days, > >> and in no patient has the disease recurred. There have been no > >> adverse effects and no complications. > >> > >> Because herpes virus disorders may cause excessive suppressor > >> T-cell activity (1) and because suppressor T cells have H-2 > >> receptors, (2) this excessive activity may be partially blocked > >> by cimetidine. Suppressor T cells may secrete lymphokines that > >> may be... > >> > >> http://www.annals. org/content/ 99/3/410. 2.extract > >> <http://www.annals.org/content/99/3/410.2.extract> > >> There are more excerpts out there if you do a search for > >> Goldstein and Cimetidine. In some places he talks about a 20% > >> success rate in his CFS patients. > >> > >> > >> > >> No virus found in this incoming message. > >> Checked by AVG -www.avg.com <http://www.avg.com/> > >> Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 > >> > >> > > > > > > > > > > > > No virus found in this incoming message. > > Checked by AVG - www.avg.com > > Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2010 Report Share Posted August 16, 2010 Hi Barb /all , I do wonder why you contracted HP and hubby didn’t and hasn’t . I don’t think it’s just a case of bumping into the pathogen but how you have developed susceptibly to infection … I remember reading an account of how Mexican workers in a food outlet tested positive for many health destroying parasites /pathogens [stool test] yet remained unaffected ..Its also a fact than in parts of the world HP is endemic with no obvious problems to those affected. It is suspected that HP was with us before we were human!!! So why is it a pathogen only in some people? Here’s one theory , that gels very well with my findings ..Our illness stems from a gut dysbiosis , restoring gut flora to what is considered normal is now the holly grail of medicine [or should be]..See my comments to Dr Mercloa’s articles in “current medical thinking I” part of my site ..And in "normal flora" sect on how our commensal flora tweak the immune system to provide our immune response .. Best An alternative hypothesis is that microorganisms that cause lifelong infections can ill afford to express virulence factors that directly cause disease, because the risk of losing the host is too great. Rather, we propose that gastroduodenal disease associated with H. pylori infection is predominantly a result of inappropriately regulated gastric immune responses to the infection. In this model, the interactions between the immune/inflammatory response, gastric physiology, and host repair mechanisms would dictate the disease outcome in response to infection. THE DISEASE SPECTRUM OF HELICOBACTER PYLORI: The Immunopathogenesis of Gastroduodenal Ulcer and Gastric Cancer http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.micro.54.1.615 http://www.yeast-candida-infections-uk.co.uk/autism-is-increasing-exponentially On 15/08/2010 12:30, egroups1bp wrote: Speaking of Ulcers- My hubby and I went to Mexico in Feb this year and I contracted h. pylori... or put it this way ( in case it was latent and just decided to show symptoms)... I became symptomatic about 10 days after returning. Waking up at night with a gnawing sensation in my gut- feeling sicj about 1 hr after eating.. etc. Quest diagnostics confirmed positive for h.pylori by blood test ( antibodies). I took a modified version of the PrevPac ( 1 G clarithromycin, 2G amoxicillin % 60 mg Nexium with 8 Oz Kefir and 500,000 cfu Nystatin) daily for 2 .5 weeks... then 6 weeks later tested Negative for H. Pylori antigen by Fecal Test. My guts been great since. I imagine that killed some Lyme if there was any unexposed as well!. Bonus. Barb > >> I've talked about this before but thought it might be a good time > >> to revisit Cimetidine (Tagament) as an anti-viral medication (a > >> benign one at that). > >> Dr. Jay Goldstein in Los Angeles reported that Cimetidine could > >> cure the Mononuecleosis virus within 1 to 2 days. And he became > >> so frustrated at the lack of attention to this finding that he > >> more or less gave up trying to get people to listen. > >> However, I recently was doing a search on "Cimetidine virus" and > >> came across numerous claims from people who find it helps stop or > >> slow their Herpes outbreaks. (apparently, mono is a type of > >> herpes virus.) > >> So with all the talk of the new XMRV retro-virus, it may be time > >> to take another look at Cimetidine or other drugs that affect > >> T-cells and their receptors. > >> *From ANNALS OF INTERNAL MEDICINE* > >> > >> > >> Cimetidine and Mononucleosis > >> > >> 1. JAY A. GOLDSTEIN > >> <http://www.annals.org/search?author1=JAY+A.+GOLDSTEIN & sortspec=date & submit=Submit>, > >> M.D. > >> > >> *Excerpt* > >> > >> ** > >> > >> To the editor: For 2 years I have been treating patients in my > >> family practice who have mononucleosis with cimetidine, 300 mg > >> three times a day for 5 days. Twenty-nine of thirty-two patients > >> have had almost complete remission of symptoms in 1 or 2 days, > >> and in no patient has the disease recurred. There have been no > >> adverse effects and no complications. > >> > >> Because herpes virus disorders may cause excessive suppressor > >> T-cell activity (1) and because suppressor T cells have H-2 > >> receptors, (2) this excessive activity may be partially blocked > >> by cimetidine. Suppressor T cells may secrete lymphokines that > >> may be... > >> > >> http://www.annals. org/content/ 99/3/410. 2.extract > >> <http://www.annals.org/content/99/3/410.2.extract> > >> There are more excerpts out there if you do a search for > >> Goldstein and Cimetidine. In some places he talks about a 20% > >> success rate in his CFS patients. > >> > >> > >> > >> No virus found in this incoming message. > >> Checked by AVG -www.avg.com <http://www.avg.com/> > >> Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 > >> > >> > > > > > > > > > > > > No virus found in this incoming message. > > Checked by AVG - www.avg.com > > Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: 07/25/10 07:36:00 > > > > > No virus found in this incoming message. Checked by AVG - www.avg.com Version: 9.0.851 / Virus Database: 271.1.1/3073 - Release Date: 08/15/10 07:35:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 17, 2010 Report Share Posted August 17, 2010 IMO, there's not much of a case for damage. It's possible it could exist in some. More likely, I believe, all symtpoms are reversable in everyone with me/cfs. > Its just such a shame. Retroviral infections are so serious and damage begins > early after infection (like 2 weeks or something). I can only wonder what will > become of me, starting the meds 18 yrs later! I had hoped more doctors would > take this seriously now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 17, 2010 Report Share Posted August 17, 2010 i have spoken to a retroviroligst, who tells me there can be damage, including lymph tissue atrophy and other things. i cannot remember what else and have lost the email. i dont know if this will happen to us or not....maybe it is mostly reversible damage. but i know people who have had cancer and heart attacks due to CFS so i am not sure if its all reversible for everyone. sue From: hodolog1ca <usenethod@...>infections Sent: Tue, August 17, 2010 1:48:01 AMSubject: [infections] Re: Cimetidine/Tagament for Virus IMO, there's not much of a case for damage. It's possible it could exist in some. More likely, I believe, all symtpoms are reversable in everyone with me/cfs.> Its just such a shame. Retroviral infections are so serious and damage begins > early after infection (like 2 weeks or something). I can only wonder what will > become of me, starting the meds 18 yrs later! I had hoped more doctors would > take this seriously now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 19, 2010 Report Share Posted August 19, 2010 Hi : Hubby was tested at the same time I was at the same lab and he was negative. I agree with you 100% about gut and immunity. Actually I think my gut/digestive tract / bowels are in the best shape they've ever been in. But that doesn't mean it's in great shape either (it was in such terrible shape when Lyme was active) I have a candida panel (IgA, IgM, IgG)done every couple of years, and I was negative for the first time in about 10 years - tested at the same time I was tested for HP. You know my spleen status is a mystery- right? None present on a CT scan- but a suspected smaLL auxillary spleen attached to my pancreas... SO I'm not sure I'm the best subject to generalize about immunity - as mine is suspect anyway. I have had some massive infections in my past - some infections my immune system elevates and responds to and some it just doesn;t. I've had 3 major surgeries on my gut dating back to 1956 ( born in 1948 operated on in 1956 exploratory surgery - they found a kidney flopping around in my body cavity) and then another OP in 1976 when adhesions from the 1954 op looped a section of intestine ( That was mis dx as hysterical pregnancy and I almost died). I'll read your references though Thanks. B > > > >> I've talked about this before but thought it might be a good time > > > >> to revisit Cimetidine (Tagament) as an anti-viral medication (a > > > >> benign one at that). > > > >> Dr. Jay Goldstein in Los Angeles reported that Cimetidine could > > > >> cure the Mononuecleosis virus within 1 to 2 days. And he became > > > >> so frustrated at the lack of attention to this finding that he > > > >> more or less gave up trying to get people to listen. > > > >> However, I recently was doing a search on " Cimetidine virus " and > > > >> came across numerous claims from people who find it helps stop or > > > >> slow their Herpes outbreaks. (apparently, mono is a type of > > > >> herpes virus.) > > > >> So with all the talk of the new XMRV retro-virus, it may be time > > > >> to take another look at Cimetidine or other drugs that affect > > > >> T-cells and their receptors. > > > >> *From ANNALS OF INTERNAL MEDICINE* > > > >> > > > >> > > > >> Cimetidine and Mononucleosis > > > >> > > > >> 1. JAY A. GOLDSTEIN > > > >> > > <http://www.annals.org/search?author1=JAY+A.+GOLDSTEIN & sortspec=date & submit=Subm\ it > > <http://www.annals.org/search?author1=JAY+A.+GOLDSTEIN & sortspec=date & submit=Subm\ it>>, > > > >> M.D. > > > >> > > > >> *Excerpt* > > > >> > > > >> ** > > > >> > > > >> To the editor: For 2 years I have been treating patients in my > > > >> family practice who have mononucleosis with cimetidine, 300 mg > > > >> three times a day for 5 days. Twenty-nine of thirty-two patients > > > >> have had almost complete remission of symptoms in 1 or 2 days, > > > >> and in no patient has the disease recurred. There have been no > > > >> adverse effects and no complications. > > > >> > > > >> Because herpes virus disorders may cause excessive suppressor > > > >> T-cell activity (1) and because suppressor T cells have H-2 > > > >> receptors, (2) this excessive activity may be partially blocked > > > >> by cimetidine. Suppressor T cells may secrete lymphokines that > > > >> may be... > > > >> > > > >> http://www.annals. org/content/ 99/3/410. 2.extract > > > >> <http://www.annals.org/content/99/3/410.2.extract> > > > >> There are more excerpts out there if you do a search for > > > >> Goldstein and Cimetidine. In some places he talks about a 20% > > > >> success rate in his CFS patients. > > > >> > > > >> > > > >> > > > >> No virus found in this incoming message. > > > >> Checked by AVG -www.avg.com <http://www.avg.com/> > > > >> Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: > > 07/25/10 07:36:00 > > > >> > > > >> > > > > > > > > > > > > > > > > > > > > > > > > No virus found in this incoming message. > > > > Checked by AVG - www.avg.com > > > > Version: 9.0.851 / Virus Database: 271.1.1/3027 - Release Date: > > 07/25/10 07:36:00 > > > > > > > > > > > > > > > > > > > > > > > No virus found in this incoming message. > > Checked by AVG - www.avg.com > > Version: 9.0.851 / Virus Database: 271.1.1/3073 - Release Date: 08/15/10 07:35:00 > > > Quote Link to comment Share on other sites More sharing options...
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