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some amy yasko comments i encounter interesting...

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Because Dr. Hoffer, Md that helped my son so much with his info regarding niacin and vitamin C long before Amy, and thanks God i did it and yes it did work for us witout paying so much for testing. my son i guess was high in kynurenine but I still continued to give him until he went over the exitatory period and the infection I guess was over because then he just come down and overall improve his mental and body health as dr. Hoffer predicted. Or maybe the introduction of lumbrokinase was the key, overall it worked fine with my extra idea of introducing lumbrokinase to the soup.

Dr. Hoffer told me that treatment plan with b3 and vit C for free! and I shared with everyone else for free as well.

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Quinolinic acid was found to be substantially elevated in patients with Borrelia burgdorferi (Lyme) infection aid has been postulated to play a role in contributing to neurological and cognitive defects associated with Lyme disease.

It is of importance to try to look at why you may have elevated activity in the tryptophan breakdown pathway in the first place. Decreased methylation, increased ID0 (an enzyme that is also effected by methylation and other factors), and chronic streptococcal or even B. burgdorferi (lyme) infection can lead to stimulation of this pathway.

The final breakdown product of the tryptophan pathway is niacinamide.

This B vitamin has been reported to have antimicrobial effects. It may be that

the body is trying to address bacterial infection by breaking down tryptophan

into niacinamide to help with infection. In some cases I have not found that the

use of high dose B6 or P5P is always helpful.

It can actually cause more overstimulatory or OCD type behaviors.

While kynurenic acid is calming for neurotransmitters, the product that kynurenines are converted to by B6 is

quinolinic acid. Quinolinic acid is an excitotoxin. So if you have high

kynurenine and add B6 you can generate quinolinic acid which acts as an

excitotoxin and can aggravate the nervous system. Increased levels of

quinolinic acid have been implicated in Alzheimerds disease as well as with

respect to excitotoxin damage of nerves.

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Lyme infection in the body. Lyme disease has been implicated in a number of

neurological conditions. Cat's claw is reported to be helpful for viral issues

as well as for Lyme. Artemisia (wormwood) has also shown activity against

Lyme. Wormwood is a component of Paradex that was already mentioned

with respect to other parasitic infections. In addition, tick support RNAs and

IMF 2 should help to support the body. Chronic issues with Lyme may overlap

with thyroid dysfunction.

From: Sent: Saturday, May 31, 2008 6:36 PMTo: 'BorreliaMultipleInfectionsAndAutism 'Subject: some amy yasko comments i encounter interesting...

Because Dr. Hoffer, Md that helped my son so much with his info regarding niacin and vitamin C long before Amy, and thanks God i did it and yes it did work for us witout paying so much for testing. my son i guess was high in kynurenine but I still continued to give him until he went over the exitatory period and the infection I guess was over because then he just come down and overall improve his mental and body health as dr. Hoffer predicted. Or maybe the introduction of lumbrokinase was the key, overall it worked fine with my extra idea of introducing lumbrokinase to the soup.

Dr. Hoffer told me that treatment plan with b3 and vit C for free! and I shared with everyone else for free as well.

.

Quinolinic acid was found to be substantially elevated in patients with Borrelia burgdorferi (Lyme) infection aid has been postulated to play a role in contributing to neurological and cognitive defects associated with Lyme disease.

It is of importance to try to look at why you may have elevated activity in the tryptophan breakdown pathway in the first place. Decreased methylation, increased ID0 (an enzyme that is also effected by methylation and other factors), and chronic streptococcal or even B. burgdorferi (lyme) infection can lead to stimulation of this pathway.

The final breakdown product of the tryptophan pathway is niacinamide.

This B vitamin has been reported to have antimicrobial effects. It may be that

the body is trying to address bacterial infection by breaking down tryptophan

into niacinamide to help with infection. In some cases I have not found that the

use of high dose B6 or P5P is always helpful.

It can actually cause more overstimulatory or OCD type behaviors.

While kynurenic acid is calming for neurotransmitters, the product that kynurenines are converted to by B6 is

quinolinic acid. Quinolinic acid is an excitotoxin. So if you have high

kynurenine and add B6 you can generate quinolinic acid which acts as an

excitotoxin and can aggravate the nervous system. Increased levels of

quinolinic acid have been implicated in Alzheimerds disease as well as with

respect to excitotoxin damage of nerves.

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