Guest guest Posted July 23, 2008 Report Share Posted July 23, 2008 I have trying to compile info on the Valkion and Cold Laser therapies so we would have a basic research document available. Since Lorina has posted about the Valkion, thought I'd post up my latest compilation of research. I can not thank Dr. Klinghardt, Dr Amy, Dr. , Lorina, Limin, Natasa and many others as we worked off-lists to gather info and research in our late night quests for researching what would be best for our children. There is not a lot of info out there right now on it's use with ASD but if you break down some of the cellular level issues, it really supports this treatment. I've researched, including some off-list e-mails with ASD moms happy with it's use with their children. Hope this info will help someone wanting to look into this further. The Valkion is expensive, but less than what the HBOT would have run us, and we can use it from home...which is a major plus for this busy family. Rita ----Forwarded ------ I am looking forward to hearing Dr. Klinghardt and other highly regarded professionals demonstrate and talk about several things like the Valkion an cold laser treatments at his upcoming Autism 2008 conference. http://www.klinghardt.org/workshops.asp Thought I'd post some of the research our group has been putting together to help anyone else that may be considering this. I personally appreciated the international medical studies from tyoma.com that I "*" below, especially noteworthy to our ASD children ------Dr. Klinghardt's - Copied from BioTools: "Energy Medicine for Autistic ChildrenPractical Non-Biochemical Solutions, Specific Developments andRecommendations by Dietrich Klinghardt, MD,PhD1. Increase Restorative SleepThe Problem: within 3 feet of the power supply in the bedroom wall -and within 1.6 miles of a cell phone transmitter - children haveseverely disturbed EEGs, decreased melatonin production and blockedactivity of detoxification enzymes in the brain, gut, liver andkidneys The solution: the "Sleep Sanctuary" technology from BioToolsevolved from the German teaching of the Institute of Baubiology. Wehave created an esthetic Faraday cage which decreases the EMFexposure of the child to one tenthousands– a silver coated mosquitonet and grounding cloth Result: instantly normalization of the childs EEG, Heart RateVariability and numerous hormonal, cytokine and other lab parameters.It improves blood and tissue oxygenation and tissue ph. Permanentbehavioral and mental improvements in the child are dramatic andobserved within days to weeks 2. Heal the brain The problem: The astrocytes are toxic. The blood brain barrier isstuck open. The mirror neurons – responsible for normal emotional andmental responses – are toxic and dysfunctional. There is no groomingof excessive neurons, etc. The Solutions: 1.The "Valkion": a Swedish device which creates energized "singletoxygen" for inhalation. This energized oxygen crosses the blood brainbarrier rapidly and effectively. The problem: in ASD children with Lyme disease, mycoplasma, moldand viral infections the endothelium is lined with fibrin, delayingthe delivery of oxygen to the tissues from 2 seconds to 5.4 minutes.The tissues are oxygen starved. This is the most effective device todeliver oxygen and energy to the brain, to the spinal chord and thekidneys. In our work with ASD children this is comparable with - ormore effective - then HBOT. 2. Place the "Light Shield" over the brain. The visiblemonochromatic light stimulates brain function via the visceral-cutaneous reflex. The invisible IR light penetrates the skull andreaches 7 cm into the brain - reaching most of the higher cognitiveareas easily. It increases bloodflow, venous and lymphatic drainage,metabolic activity of the brain cells, and activates the intrinsicdetox mechanisms of the brain. The "light shield" also increases> medication uptake, a most important issue that has been overlookedby most. It also has a strong direct anti-viral effect and isphototactic – it strongly attracts NK cells into the illuminatedareas. The result: the brain recovers faster, with less side effects.Appropriate treatments that did not seem to work before, can work nowrapidly and profoundly. 3. Increase the Filtration Rate of the Kidneys The Problem: the basal membranes of the kidney become inflamed andswollen as soon as mercury, lead and other toxins are filtered duringchelation therapy. The nephrons stay in an allergic, poorlyfiltrating state, as long as the metal mobilizing medication is given The solutions: 1. the BioTools "Light Shield". By placing the device over thekidneys normal filtrating function resumes within less then an hour.The device should be used daily during active detox and during allcrises. 2. The Swiss "Toxaway" electric foot bath uses an electrochemicalprocess to stimulate the kidney and liver meridian at the feet toeffectively increase toxin elimination activity of both organs. Thereis also direct active lymphatic excretion of toxins across the solesof the feet. This device is superior to other comparable instruments(the secret is in the electrodes) Result: dramatic shortening of the overall treatment time andimproved success rate in stubborn cases. It minimizes thefeared "healing crisis" after starting a chelation program 4. Improve phase-I and phase-II liver enzyme activity Problem: most of the ASD children have impaired liver enzymefunction at different locations (p450, acetylation, sulfation,glutathione-S-transferase) Solution: the BioTools "Light Shield". By placing the device overthe kidneys ATP inside the cells increases significantly and the celldoes its job more effectively. The light also turns on the cellorganelles: the peroxisomes, the mitochondria, the Golgi apparatus,etc. It also enlarges the bile ducts, the arterioles and the lymphducts in the liver by blocking the sympathetic nervous system andstimulating the parasympathetics. Result: in spite of numerous gene polymorphisms of the detox genes,the child starts eliminating neurotoxins and heavy metals at ratescomparable or superior to normal children." A google search of "Valkion", "activated air", "singlet oxygen" and "oxygen therapies" is a good thing when looking into this. -------Dr. from polyvalk.com http://www.subtleenergies.com/ormus/tw/singlet.htm -------Valkion patent page à description:http://tinyurl.com/5a8thbÒÉEven though singlet oxygen quickly returns to oxygen in its groundstate, by studying the effects of the described device, it can bedemonstrated that a medium, liquid or gas, in which singlet oxygenhas been formed, has a certain altered state, at least for a limitedperiodÉÓ------Shorthand explanation fromhttp://www.breathing.com/articles/oxygen-therapies.htmOxidative Response: The cellular defense against Oxidative Stress isthe Oxidative Response. The Oxidative Response System (or cellresponsesystem) protects against, and repairs, Oxidative Stress damage. Thisisaccomplished mainly through enzyme and coenzyme production. TheOxidative Response is initiated by signal transduction sequencesinducedby singlet oxygen. Singlet oxygen is an activated oxygen species, butnot a free radical. Signaling proteins then trigger the cellresponse.Cell response results include, but are not limited to:Protection against free radical damageRepair of damage caused by free radicalsImproved Oxygen utilizationImproved cell energy productionImproved cell metabolismFor optimal cell metabolism, a strong Oxidative Response and lowOxidative Stress are essential.Also:Singlet Oxygen is also produced in human cells as a by-product ofmetabolism. Here, it can be harmful and cause cell damage, as itacts as a Ôfree radical«. Yet Singlet Oxygen has a very shortlifespan, and returns to its ground state within a fraction of asecond.In a humid atmosphere, its lifespan comprises only a few hundredthousandths of a second. This means that no Singlet Oxygen can leavethe equipment and, consequently, cannot harm any organismÉ.ÉValkion imitates nature. They have constructed an activationchamber, where an artificial light source acts together with a highefficiency heat and light resistant Ôphotosensitizer«. With anair pump, a stream of activated air is created. This may then beinhaled, with or without the aid of an inhalation mask or nasalcannula for research. Applications for research purposes vary. The findingsshow that moist air is essential; that is why every unit is equippedwith a humidifier giving the activated air a humidity level of atleast 85%(depending on the humidity and temperature of the ambient air). --------From: http://www.rangeguide.net/valkion.htm(Note: Called a few days ago for current pricing (approx $5,000. +shp. Over $1,000 more than BioTools-again fluctuates with the $.He's an elder to some church and you would also have to join theirchurch....NOT going to do that so if I'm able to swing this I'll begetting mine from BioTools.) *--------Ukrainian website with links to medical trials in Ukraine:(This was some GREAT international medical studies:Investigation of "Valkion Factors Effect on Energy Metabolism and onOxygen Free Radical Generation" have been fulfilled at the followinginstitution:)http://www.tyoma.com.ua/investigation_2_2.html"Our company, situated in Ukraine, is scientific and selling partnerof Polyvalk AB (Gothenburg, Sweden) à Valkion units producer. In 1997 wehave Registered Valkion unit in Ukraine. Since that time we havesold a lot of units to Medical Universities, clinics and private people.We have more than 100 reports from our partners on Pulmonology,Gastroenterology, Traumatology, Dermatology, Radiology, Nephrologyand urology, Obstetrics and gynaecology, Gerontology, Cardiology,Hematology, Endocrinology, Neurology, Immunology, Infectology,Surgery.These researches were done in accordance to international terms ofclinical investigations (2-3 groups with more than 20 patients withsimilar disease; one group treated with standard treatment, next àwith Valkion therapy (or combined à Valkion therapy and standardtreatment) and sometimes (when it is possible) à third group àuses placebo) and published in Ukrainian, European and Asianscientific journals and as materials of different scientific conferences.Swedish in vitro and animal studies:Free Radical Biology and MedicineVolume 27, Issues 11-12, December 1999, Pages 1203-1207Harmful singlet oxygen can be helpfulLillemor Mattsson HultŽna, Marc Holmstršma and BassamSoussiCorresponding Author Contact Information, WallenbergLaboratory for Cardiovascular Research, University of Gšteborg, SahlgrenskaUniversity Hospital, Gšteborg, SwedenHighly reactive harmful singlet oxygen O2(1Î"g)can be helpful whilerelaxing to its triplet ground state O2(3Σg-). The energy emittedduring this relaxation from the excited energy state is discernableat 634 nm. We report here on the effect of this energy as photonillumination and as energy transfer in air on the production ofreactive oxygen species (ROS) by human monocytes, measured asisoluminol-enhanced chemiluminescence. We demonstrate up to 60%decrease in the secretion of ROS after 2-min illumination of themonocytes stimulated with phorbol myristate acatate (PMA). Theresults provide in vitro documentation of the utility of singlet oxygenenergy in modifying cellular behaviour.Author Keywords: Human monocytes; Singlet oxygen; Reactive oxygenspecies; Chemiluminescence; Oxidative stress; Photodynamic therapy;Free radicals PMID: 10641712 full text: http://tinyurl.com/6gt4qvPreservation of rat skeletal muscle energy metabolism by illuminationAnn LindgŒrd, Jonas Lundberg, Olivier Rakotonirainy, Elanderand Bassam Soussi. Department of Surgery and Plastic Surgery,Bioenergetics Group, Wallenberg Laboratory, Sahlgrenska UniversityHospital, Gštenborg University, Gštenborg S-143-45, SwedenSkeletal muscle viability is crucially dependent on the tissuelevels of its high energy phosphates. In this study we investigated theeffect of the preservation medium Perfadex and illumination with SingletOxygen Energy (SOE). Singlet oxygen can be produced photochemicallyby energy transfer from an excited photosensitizer. The energy emittedfrom singlet oxygen upon relaxation to its triplet state is capturedas photons at 634 nm and is here referred to as SOE. Rat hind limbrectus femoris muscles were preserved for five hours at 22 ¡C in Perfadex,saline, SOE illuminated Perfadex or SOE illuminated saline. Extractsof the muscles were analysed by 31P NMR. Data were analysed using two-way analysis of variance and are given as mean values (μmol/g dryweight) ± SEM. The ATP concentration was higher (p = 0.006) insaline groups (4.52) compared with Perfadex groups (2.82). Therewas no statistically significant difference in PCr between the salinegroups (1.25) and Perfadex groups (0.82). However, there were higher (p =0.003) ATP in the SOE illuminated groups (4.61) compared with thenon-illuminated groups (2.73). The PCr was also higher (p < 0.0001)in the SOE illuminated groups (1.89) compared with the non-illuminatedgroups (0.18). In conclusion, Perfadex in this experimental modelwas incapable of preserving the high energy phosphates in skeletalmuscle during 5 hours of ischemia. Illumination with SOE at 634 nm improvedthe preservation potential, in terms of a positive effect on the energystatus of the muscle cell. PMID: 12672510 [PubMed - indexed for MEDLINE]Transplant Proc. 2005 Jan-Feb;37(1):518-20.Singlet oxygen energy illumination during moderate cold ischemiaprolongs the survival of concordant hamster xeno-heart transplants. Lukes DJ, Skogsberg U, Nilsson A, Lundgren A, Olausson M,Soussi B.Department of Surgery and Transplantation, Wallenberg Laboratory forCardiovascular Research, Gšteborg, Sweden.INTRODUCTION: Singlet oxygen energy (SOE) is a potent inhibitorof reactive oxygen species (ROS) in vitro and in vivo in certain doseranges and can improve the levels of high-energy phosphates (HEP) inconcordant hamster xeno-heart transplants. Some data indicate that acertain degree of cold ischemia (CI) might be beneficial toxenotransplants. We investigated if SOE illumination of hamsterxeno-hearts during moderate cold ischemia (CI) improved graftsurvival.MATERIALS AND METHODS: Eighteen hearts from Golden Syrian hamsters(70 to 80 g) were subjected to 8 hours of CI in cold (+4 degrees C)saline solution (NaCL, 0.9%) before heterotopic cervical transplantation to rats (220 g). Among the treatment group (n = 8), SOE wasproduced by illuminating the hearts for 10 minutes every 30 minutes withphotons at lambda 634 nm with the Oxylight equipment. Graft function wasevaluated every 6 hours after transplantation with digital examuntil cessation of heart beats. RESULTS: The graft survival ofSOE-illuminated ischemic hamster xenografts was 2.34 +/- 0.56 versus1.15 +/- 0.37 days in the control group (P < .05). All heartsdisplayed immediate graft function versus 70% in the controls (NS).CONCLUSIONS:SOE illumination at lambda 634 nm during moderate cold ischemia (+4degrees C) can improve the survival of concordant hamster xeno-hearttransplants. The exact mechanism(s) are currently unknown, but theeffect might in part be exerted by a combination of reducedproduction of ROS and increased oxidative phosphorylation.Publication Types: * Research Support, Non-U.S. Gov't PMID: 15808696 [PubMed - indexed for MEDLINE] Non-published research (study in Spanish):Therapy Valkion, its effect on non-traumatic joint pain.Dra. Flora Mar'a Hern‡ndez Pedraza, Dr. Orlando S‡nchezFreire . Orlando Freire. Especialista de 1er Grado enMedicina F'sica y Rehabilitaci—n.Diplomado en FitoterapiaCl'nicaÉ.Clinic Natural and Traditional Medicine. Santa Clara.Santa Clara. Villa Clara. Villa Clara.We studied a total of 300 patients with non-traumatic joint painfrom the clinic of traditional medicine and natural Santa Clara in thefirst period from February 2000 until February 1, 2001. 3 groups wereformed with 100 patients each: a control group with acupuncture and twotanks, one with phototherapy and another with VALKION therapy. The averagenumber of days of treatment was 16 days, ending two months oftreatment patients treated with VALKION had no relapses and decreasedconsumption of drugs and therefore believe that this therapy should be used inpatients with this condition because it is odourless and harmless tothe patient as well as by its high therapeutic effectiveness. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 23, 2008 Report Share Posted July 23, 2008 Gayatri, Dr. Klinghardt will be talking about and demonstrating it at his conference and I was planning on asking him this very question. The direct report from an ASD mom I've been exchanging e-mails with is very good. I have also been told by BioTools that they have seen 2 year advances in education in 6 months. I am mainly looking at benefiting his few remaining health issues. The educational part would also be big for us (behaviorally and socially he's doing great. He's in a tough general ed school and educationally he's still behind 2 years in some subjects. He has problems with reading comprehension and math, especially story problems. We've come a long way from 4 years ago being told by the UW he was retarded and would probably not read. In his recent 3 year re-evaluation they dropped the retarded label and said they would have never put the old file and new file together as the same kid. As the only therapy he has received was 1/2 hour a week of speech this improvement is all BioMeds!) I'll post more about it in a few weeks after the conference and reports from the families that ordered it. Rita > > > > I have trying to compile info on the Valkion and Cold Laser > therapies so we would have a basic research document available. Since > Lorina has posted about the Valkion, thought I'd post up my latest > compilation of research. I can not thank Dr. Klinghardt, Dr Amy, Dr. > , Lorina, Limin, Natasa and many others as we worked > off-lists to gather info and research in our late night quests for > researching what would be best for our children. There is not a lot of > info out there right now on it's use with ASD but if you break down > some of the cellular level issues, it really supports this treatment. > I've researched, including some off-list e-mails with ASD moms happy > with it's use with their children. Hope this info will help someone > wanting to look into this further. The Valkion is expensive, but less > than what the HBOT would have run us, and we can use it from > home...which is a major plus for this busy family. > > Rita > > ----Forwarded ------ > > I am looking forward to hearing Dr. Klinghardt and other highly > regarded professionals demonstrate and talk about several things like > the Valkion an cold laser treatments at his upcoming Autism 2008 > conference. > > http://www.klinghardt.org/workshops.asp > > Thought I'd post some of the research our group has been putting > together to help anyone else that may be considering this. I > personally appreciated the international medical studies from > tyoma.com that I " * " below, especially noteworthy to our ASD children > > > > ------Dr. Klinghardt's - Copied from BioTools: > > " Energy Medicine for Autistic Children > > Practical Non-Biochemical Solutions, Specific Developments and > > Recommendations by Dietrich Klinghardt, MD,PhD > > 1. Increase Restorative Sleep > > The Problem: within 3 feet of the power supply in the bedroom wall - > > and within 1.6 miles of a cell phone transmitter - children have > > severely disturbed EEGs, decreased melatonin production and blocked > > activity of detoxification enzymes in the brain, gut, liver and > > kidneys > > The solution: the " Sleep Sanctuary " technology from BioTools > > evolved from the German teaching of the Institute of Baubiology. We > > have created an esthetic Faraday cage which decreases the EMF > > exposure of the child to one tenthousands– a silver coated mosquito > > net and grounding cloth > > Result: instantly normalization of the childs EEG, Heart Rate > > Variability and numerous hormonal, cytokine and other lab parameters. > > It improves blood and tissue oxygenation and tissue ph. Permanent > > behavioral and mental improvements in the child are dramatic and > > observed within days to weeks > > 2. Heal the brain > > The problem: The astrocytes are toxic. The blood brain barrier is > > stuck open. The mirror neurons – responsible for normal emotional and > > mental responses – are toxic and dysfunctional. There is no grooming > > of excessive neurons, etc. > > The Solutions: > > 1.The " Valkion " : a Swedish device which creates energized " singlet > > oxygen " for inhalation. This energized oxygen crosses the blood brain > > barrier rapidly and effectively. > > The problem: in ASD children with Lyme disease, mycoplasma, mold > > and viral infections the endothelium is lined with fibrin, delaying > > the delivery of oxygen to the tissues from 2 seconds to 5.4 minutes. > > The tissues are oxygen starved. This is the most effective device to > > deliver oxygen and energy to the brain, to the spinal chord and the > > kidneys. In our work with ASD children this is comparable with - or > > more effective - then HBOT. > > 2. Place the " Light Shield " over the brain. The visible > > monochromatic light stimulates brain function via the visceral- > > cutaneous reflex. The invisible IR light penetrates the skull and > > reaches 7 cm into the brain - reaching most of the higher cognitive > > areas easily. It increases bloodflow, venous and lymphatic drainage, > > metabolic activity of the brain cells, and activates the intrinsic > > detox mechanisms of the brain. The " light shield " also increases > > > medication uptake, a most important issue that has been overlooked > > by most. It also has a strong direct anti-viral effect and is > > phototactic – it strongly attracts NK cells into the illuminated > > areas. > > The result: the brain recovers faster, with less side effects. > > Appropriate treatments that did not seem to work before, can work now > > rapidly and profoundly. > > 3. Increase the Filtration Rate of the Kidneys > > The Problem: the basal membranes of the kidney become inflamed and > > swollen as soon as mercury, lead and other toxins are filtered during > > chelation therapy. The nephrons stay in an allergic, poorly > > filtrating state, as long as the metal mobilizing medication is given > > The solutions: > > 1. the BioTools " Light Shield " . By placing the device over the > > kidneys normal filtrating function resumes within less then an hour. > > The device should be used daily during active detox and during all > > crises. > > 2. The Swiss " Toxaway " electric foot bath uses an electrochemical > > process to stimulate the kidney and liver meridian at the feet to > > effectively increase toxin elimination activity of both organs. There > > is also direct active lymphatic excretion of toxins across the soles > > of the feet. This device is superior to other comparable instruments > > (the secret is in the electrodes) > > Result: dramatic shortening of the overall treatment time and > > improved success rate in stubborn cases. It minimizes the > > feared " healing crisis " after starting a chelation program > > 4. Improve phase-I and phase-II liver enzyme activity > > Problem: most of the ASD children have impaired liver enzyme > > function at different locations (p450, acetylation, sulfation, > > glutathione-S-transferase) > > Solution: the BioTools " Light Shield " . By placing the device over > > the kidneys ATP inside the cells increases significantly and the cell > > does its job more effectively. The light also turns on the cell > > organelles: the peroxisomes, the mitochondria, the Golgi apparatus, > > etc. It also enlarges the bile ducts, the arterioles and the lymph > > ducts in the liver by blocking the sympathetic nervous system and > > stimulating the parasympathetics. > > Result: in spite of numerous gene polymorphisms of the detox genes, > > the child starts eliminating neurotoxins and heavy metals at rates > > comparable or superior to normal children. " > > > > A google search of " Valkion " , " activated air " , " singlet oxygen " and > > " oxygen therapies " is a good thing when looking into this. > > -------Dr. from polyvalk.com > > http://www.subtleenergies.com/ormus/tw/singlet.htm > > > > -------Valkion patent page à description: > > http://tinyurl.com/5a8thb > > ÒÉEven though singlet oxygen quickly returns to oxygen in its ground > > state, by studying the effects of the described device, it can be > > demonstrated that a medium, liquid or gas, in which singlet oxygen > > has been formed, has a certain altered state, at least for a limited > > periodÉÓ > > > > ------Shorthand explanation from > > http://www.breathing.com/articles/oxygen-therapies.htm > > > > Oxidative Response: The cellular defense against Oxidative Stress is > > the Oxidative Response. The Oxidative Response System (or cell > > response > > system) protects against, and repairs, Oxidative Stress damage. This > > is > > accomplished mainly through enzyme and coenzyme production. The > > Oxidative Response is initiated by signal transduction sequences > > induced > > by singlet oxygen. Singlet oxygen is an activated oxygen species, but > > not a free radical. Signaling proteins then trigger the cell > > response. > > > > Cell response results include, but are not limited to: > > Protection against free radical damage > > Repair of damage caused by free radicals > > Improved Oxygen utilization > > Improved cell energy production > > Improved cell metabolism > > For optimal cell metabolism, a strong Oxidative Response and low > > Oxidative Stress are essential. > > > > Also: > > Singlet Oxygen is also produced in human cells as a by-product of > > metabolism. Here, it can be harmful and cause cell damage, as it > > acts as a Ôfree radical«. Yet Singlet Oxygen has a very short > > lifespan, and returns to its ground state within a fraction of a > > second. > > In a humid atmosphere, its lifespan comprises only a few hundred > > thousandths of a second. This means that no Singlet Oxygen can leave > > the equipment and, consequently, cannot harm any organismÉ. > > ÉValkion imitates nature. They have constructed an activation > > chamber, where an artificial light source acts together with a high > > efficiency heat and light resistant Ôphotosensitizer«. With an > > air pump, a stream of activated air is created. This may then be > > inhaled, with or without the aid of an inhalation mask or nasal > > cannula for research. Applications for research purposes vary. The > findings > > show that moist air is essential; that is why every unit is equipped > > with a humidifier giving the activated air a humidity level of at > > least 85%(depending on the humidity and temperature of the ambient > air). > > > > --------From: http://www.rangeguide.net/valkion.htm > > (Note: Called a few days ago for current pricing (approx $5,000. + > > shp. Over $1,000 more than BioTools-again fluctuates with the $. > > He's an elder to some church and you would also have to join their > > church....NOT going to do that so if I'm able to swing this I'll be > > getting mine from BioTools.) > > > > > > *--------Ukrainian website with links to medical trials in Ukraine: > > (This was some GREAT international medical studies: > > Investigation of " Valkion Factors Effect on Energy Metabolism and on > > Oxygen Free Radical Generation " have been fulfilled at the following > > institution:) > > http://www.tyoma.com.ua/investigation_2_2.html > > > > " Our company, situated in Ukraine, is scientific and selling partner > > of Polyvalk AB (Gothenburg, Sweden) à Valkion units producer. In 1997 we > > have Registered Valkion unit in Ukraine. Since that time we have > > sold a lot of units to Medical Universities, clinics and private people. > > We have more than 100 reports from our partners on Pulmonology, > > Gastroenterology, Traumatology, Dermatology, Radiology, Nephrology > > and urology, Obstetrics and gynaecology, Gerontology, Cardiology, > > Hematology, Endocrinology, Neurology, Immunology, Infectology, > > Surgery. > > These researches were done in accordance to international terms of > > clinical investigations (2-3 groups with more than 20 patients with > > similar disease; one group treated with standard treatment, next à > > with Valkion therapy (or combined à Valkion therapy and standard > > treatment) and sometimes (when it is possible) à third group à > > uses placebo) and published in Ukrainian, European and Asian > > scientific journals and as materials of different scientific > conferences. > > > > > > Swedish in vitro and animal studies: > > Free Radical Biology and Medicine > > Volume 27, Issues 11-12, December 1999, Pages 1203-1207 > > > > Harmful singlet oxygen can be helpful > > > > Lillemor Mattsson HultŽna, Marc Holmstršma and Bassam > > SoussiCorresponding Author Contact Information, Wallenberg > > Laboratory for Cardiovascular Research, University of Gšteborg, > Sahlgrenska > > University Hospital, Gšteborg, Sweden > > > > Highly reactive harmful singlet oxygen O2(1Î " g)can be helpful while > > relaxing to its triplet ground state O2(3Σg-). The energy emitted > > during this relaxation from the excited energy state is discernable > > at 634 nm. We report here on the effect of this energy as photon > > illumination and as energy transfer in air on the production of > > reactive oxygen species (ROS) by human monocytes, measured as > > isoluminol-enhanced chemiluminescence. We demonstrate up to 60% > > decrease in the secretion of ROS after 2-min illumination of the > > monocytes stimulated with phorbol myristate acatate (PMA). The > > results provide in vitro documentation of the utility of singlet oxygen > > energy in modifying cellular behaviour. > > > > Author Keywords: Human monocytes; Singlet oxygen; Reactive oxygen > > species; Chemiluminescence; Oxidative stress; Photodynamic therapy; > > Free radicals > > > > > > PMID: 10641712 full text: http://tinyurl.com/6gt4qv > > Preservation of rat skeletal muscle energy metabolism by illumination > > > > Ann LindgŒrd, Jonas Lundberg, Olivier Rakotonirainy, Elander > > and Bassam Soussi. Department of Surgery and Plastic Surgery, > > Bioenergetics Group, Wallenberg Laboratory, Sahlgrenska University > > Hospital, Gštenborg University, Gštenborg S-143-45, Sweden > > > > Skeletal muscle viability is crucially dependent on the tissue > > levels of its high energy phosphates. In this study we investigated the > > effect of the preservation medium Perfadex and illumination with Singlet > > Oxygen Energy (SOE). Singlet oxygen can be produced photochemically > > by energy transfer from an excited photosensitizer. The energy emitted > > from singlet oxygen upon relaxation to its triplet state is captured > > as photons at 634 nm and is here referred to as SOE. Rat hind limb > > rectus femoris muscles were preserved for five hours at 22 ¡C in > Perfadex, > > saline, SOE illuminated Perfadex or SOE illuminated saline. Extracts > > of the muscles were analysed by 31P NMR. Data were analysed using two- > > way analysis of variance and are given as mean values (μmol/g dry > > weight) ± SEM. The ATP concentration was higher (p = 0.006) in > > saline groups (4.52) compared with Perfadex groups (2.82). There > > was no statistically significant difference in PCr between the saline > > groups (1.25) and Perfadex groups (0.82). However, there were > higher (p = > > 0.003) ATP in the SOE illuminated groups (4.61) compared with the > > non-illuminated groups (2.73). The PCr was also higher (p < 0.0001) > > in the SOE illuminated groups (1.89) compared with the non- illuminated > > groups (0.18). In conclusion, Perfadex in this experimental model > > was incapable of preserving the high energy phosphates in skeletal > > muscle during 5 hours of ischemia. Illumination with SOE at 634 nm > improved > > the preservation potential, in terms of a positive effect on the energy > > status of the muscle cell. > > > > > > PMID: 12672510 [PubMed - indexed for MEDLINE] > > Transplant Proc. 2005 Jan-Feb;37(1):518-20. > > > > Singlet oxygen energy illumination during moderate cold ischemia > > prolongs the survival of concordant hamster xeno-heart transplants. > > > > Lukes DJ, Skogsberg U, Nilsson A, Lundgren A, Olausson M, > > Soussi B. > > Department of Surgery and Transplantation, Wallenberg Laboratory for > > Cardiovascular Research, Gšteborg, Sweden. > > > > INTRODUCTION: Singlet oxygen energy (SOE) is a potent inhibitor > > of reactive oxygen species (ROS) in vitro and in vivo in certain dose > > ranges and can improve the levels of high-energy phosphates (HEP) in > > concordant hamster xeno-heart transplants. Some data indicate that a > > certain degree of cold ischemia (CI) might be beneficial to > > xenotransplants. We investigated if SOE illumination of hamster > > xeno-hearts during moderate cold ischemia (CI) improved graft > > survival. > > MATERIALS AND METHODS: Eighteen hearts from Golden Syrian hamsters > > (70 to 80 g) were subjected to 8 hours of CI in cold (+4 degrees C) > > saline solution (NaCL, 0.9%) before heterotopic cervical > transplantation to > > rats (220 g). Among the treatment group (n = 8), SOE was > > produced by illuminating the hearts for 10 minutes every 30 minutes with > > photons at lambda 634 nm with the Oxylight equipment. Graft function was > > evaluated every 6 hours after transplantation with digital exam > > until cessation of heart beats. RESULTS: The graft survival of > > SOE-illuminated ischemic hamster xenografts was 2.34 +/- 0.56 versus > > 1.15 +/- 0.37 days in the control group (P < .05). All hearts > > displayed immediate graft function versus 70% in the controls (NS). > > CONCLUSIONS: > > SOE illumination at lambda 634 nm during moderate cold ischemia (+4 > > degrees C) can improve the survival of concordant hamster xeno- heart > > transplants. The exact mechanism(s) are currently unknown, but the > > effect might in part be exerted by a combination of reduced > > production of ROS and increased oxidative phosphorylation. > > > > Publication Types: * Research Support, Non-U.S. Gov't > > PMID: 15808696 [PubMed - indexed for MEDLINE] > > > > > > Non-published research (study in Spanish): > > > > Therapy Valkion, its effect on non-traumatic joint pain. > > > > Dra. Flora Mar'a Hern‡ndez Pedraza, Dr. Orlando S‡nchez > > Freire . Orlando Freire. Especialista de 1er Grado en > > Medicina F'sica y Rehabilitaci—n.Diplomado en Fitoterapia > > Cl'nicaÉ.Clinic Natural and Traditional Medicine. Santa Clara. > > Santa Clara. Villa Clara. Villa Clara. > > > > We studied a total of 300 patients with non-traumatic joint pain > > from the clinic of traditional medicine and natural Santa Clara in the > > first period from February 2000 until February 1, 2001. 3 groups were > > formed with 100 patients each: a control group with acupuncture and two > > tanks, one with phototherapy and another with VALKION therapy. The > average > > number of days of treatment was 16 days, ending two months of > > treatment patients treated with VALKION had no relapses and decreased > > consumption of drugs and therefore believe that this therapy should > be used in > > patients with this condition because it is odourless and harmless to > > the patient as well as by its high therapeutic effectiveness. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 23, 2008 Report Share Posted July 23, 2008 I wanted to add to Rita's post here Dr. Derksen told me that when she was training under Klinghardt they had a patient (like 1yr old girl ASD) that had seizures. This lil girl had one while in the office and they used the Valkion on her and it brought her right out of the seizure with no side effects. Dr. Amy then went on to tell us that this same family purchased a Valkion and to this day with this and other treatments she no longer experiences seizures and is doing excellent to this date. I must add in what we have seen in 24hrs of getting our Valkion Zander used the valkion last night for the first time for only 5 mins, this morning he used it for 7 mins. I had left on errands this morning, and my husband forgot to give Zander his 3 supplements he takes (which is OK if missed here and there) BUT he didn't receive his MB-12 shot. We do notice with Zander if he doesn't get it within 4-5 days he starts to have ADD issues. so, this evening when my hubby got home he was observing Zander had asked if I had given him his shot today, and I told him NO - thought you gave it to him this morning...nope. Zander has been more focused we have seen him in a long time or the day of his MB12 shot. He is very calm and requested to have the valkion again this evening so he got another treatment before bed. (making 2 today). We are placing another video up this evening with Zander using the valkion - much better then yesterdays. I also want to add, he has had 5 big healthy BM today, and telling me his tummy feels so much better. ALL looked very healthy. I am sure its helping him move out toxins he has problems getting out normally. So this is my report after 24hrs of receiving our valkion. Lorina > > > > > > I have trying to compile info on the Valkion and Cold Laser > > therapies so we would have a basic research document available. > Since > > Lorina has posted about the Valkion, thought I'd post up my latest > > compilation of research. I can not thank Dr. Klinghardt, Dr Amy, > Dr. > > , Lorina, Limin, Natasa and many others as we worked > > off-lists to gather info and research in our late night quests for > > researching what would be best for our children. There is not a > lot of > > info out there right now on it's use with ASD but if you break down > > some of the cellular level issues, it really supports this > treatment. > > I've researched, including some off-list e-mails with ASD moms > happy > > with it's use with their children. Hope this info will help someone > > wanting to look into this further. The Valkion is expensive, but > less > > than what the HBOT would have run us, and we can use it from > > home...which is a major plus for this busy family. > > > Rita > > > ----Forwarded ------ > > > I am looking forward to hearing Dr. Klinghardt and other highly > > regarded professionals demonstrate and talk about several things > like > > the Valkion an cold laser treatments at his upcoming Autism 2008 > > conference. > > > http://www.klinghardt.org/workshops.asp > > > Thought I'd post some of the research our group has been putting > > together to help anyone else that may be considering this. I > > personally appreciated the international medical studies from > > tyoma.com that I " * " below, especially noteworthy to our ASD > children > > > > > > ------Dr. Klinghardt's - Copied from BioTools: > > > " Energy Medicine for Autistic Children > > > Practical Non-Biochemical Solutions, Specific Developments and > > > Recommendations by Dietrich Klinghardt, MD,PhD > > > 1. Increase Restorative Sleep > > > The Problem: within 3 feet of the power supply in the bedroom > wall - > > > and within 1.6 miles of a cell phone transmitter - children have > > > severely disturbed EEGs, decreased melatonin production and > blocked > > > activity of detoxification enzymes in the brain, gut, liver and > > > kidneys > > > The solution: the " Sleep Sanctuary " technology from BioTools > > > evolved from the German teaching of the Institute of Baubiology. > We > > > have created an esthetic Faraday cage which decreases the EMF > > > exposure of the child to one tenthousands– a silver coated > mosquito > > > net and grounding cloth > > > Result: instantly normalization of the childs EEG, Heart Rate > > > Variability and numerous hormonal, cytokine and other lab > parameters. > > > It improves blood and tissue oxygenation and tissue ph. Permanent > > > behavioral and mental improvements in the child are dramatic and > > > observed within days to weeks > > > 2. Heal the brain > > > The problem: The astrocytes are toxic. The blood brain barrier > is > > > stuck open. The mirror neurons – responsible for normal > emotional and > > > mental responses – are toxic and dysfunctional. There is no > grooming > > > of excessive neurons, etc. > > > The Solutions: > > > 1.The " Valkion " : a Swedish device which creates > energized " singlet > > > oxygen " for inhalation. This energized oxygen crosses the blood > brain > > > barrier rapidly and effectively. > > > The problem: in ASD children with Lyme disease, mycoplasma, mold > > > and viral infections the endothelium is lined with fibrin, > delaying > > > the delivery of oxygen to the tissues from 2 seconds to 5.4 > minutes. > > > The tissues are oxygen starved. This is the most effective > device to > > > deliver oxygen and energy to the brain, to the spinal chord and > the > > > kidneys. In our work with ASD children this is comparable with - > or > > > more effective - then HBOT. > > > 2. Place the " Light Shield " over the brain. The visible > > > monochromatic light stimulates brain function via the visceral- > > > cutaneous reflex. The invisible IR light penetrates the skull and > > > reaches 7 cm into the brain - reaching most of the higher > cognitive > > > areas easily. It increases bloodflow, venous and lymphatic > drainage, > > > metabolic activity of the brain cells, and activates the > intrinsic > > > detox mechanisms of the brain. The " light shield " also increases > > > > medication uptake, a most important issue that has been > overlooked > > > by most. It also has a strong direct anti-viral effect and is > > > phototactic – it strongly attracts NK cells into the illuminated > > > areas. > > > The result: the brain recovers faster, with less side effects. > > > Appropriate treatments that did not seem to work before, can > work now > > > rapidly and profoundly. > > > 3. Increase the Filtration Rate of the Kidneys > > > The Problem: the basal membranes of the kidney become inflamed > and > > > swollen as soon as mercury, lead and other toxins are filtered > during > > > chelation therapy. The nephrons stay in an allergic, poorly > > > filtrating state, as long as the metal mobilizing medication is > given > > > The solutions: > > > 1. the BioTools " Light Shield " . By placing the device over the > > > kidneys normal filtrating function resumes within less then an > hour. > > > The device should be used daily during active detox and during > all > > > crises. > > > 2. The Swiss " Toxaway " electric foot bath uses an > electrochemical > > > process to stimulate the kidney and liver meridian at the feet to > > > effectively increase toxin elimination activity of both organs. > There > > > is also direct active lymphatic excretion of toxins across the > soles > > > of the feet. This device is superior to other comparable > instruments > > > (the secret is in the electrodes) > > > Result: dramatic shortening of the overall treatment time and > > > improved success rate in stubborn cases. It minimizes the > > > feared " healing crisis " after starting a chelation program > > > 4. Improve phase-I and phase-II liver enzyme activity > > > Problem: most of the ASD children have impaired liver enzyme > > > function at different locations (p450, acetylation, sulfation, > > > glutathione-S-transferase) > > > Solution: the BioTools " Light Shield " . By placing the device > over > > > the kidneys ATP inside the cells increases significantly and the > cell > > > does its job more effectively. The light also turns on the cell > > > organelles: the peroxisomes, the mitochondria, the Golgi > apparatus, > > > etc. It also enlarges the bile ducts, the arterioles and the > lymph > > > ducts in the liver by blocking the sympathetic nervous system and > > > stimulating the parasympathetics. > > > Result: in spite of numerous gene polymorphisms of the detox > genes, > > > the child starts eliminating neurotoxins and heavy metals at > rates > > > comparable or superior to normal children. " > > > > > > A google search of " Valkion " , " activated air " , " singlet oxygen " > and > > > " oxygen therapies " is a good thing when looking into this. > > > -------Dr. from polyvalk.com > > > http://www.subtleenergies.com/ormus/tw/singlet.htm > > > > > > -------Valkion patent page à description: > > > http://tinyurl.com/5a8thb > > > ÒÉEven though singlet oxygen quickly returns to oxygen in its > ground > > > state, by studying the effects of the described device, it can be > > > demonstrated that a medium, liquid or gas, in which singlet > oxygen > > > has been formed, has a certain altered state, at least for a > limited > > > periodÉÓ > > > > > > ------Shorthand explanation from > > > http://www.breathing.com/articles/oxygen-therapies.htm > > > > > > Oxidative Response: The cellular defense against Oxidative > Stress is > > > the Oxidative Response. The Oxidative Response System (or cell > > > response > > > system) protects against, and repairs, Oxidative Stress damage. > This > > > is > > > accomplished mainly through enzyme and coenzyme production. The > > > Oxidative Response is initiated by signal transduction sequences > > > induced > > > by singlet oxygen. Singlet oxygen is an activated oxygen > species, but > > > not a free radical. Signaling proteins then trigger the cell > > > response. > > > > > > Cell response results include, but are not limited to: > > > Protection against free radical damage > > > Repair of damage caused by free radicals > > > Improved Oxygen utilization > > > Improved cell energy production > > > Improved cell metabolism > > > For optimal cell metabolism, a strong Oxidative Response and low > > > Oxidative Stress are essential. > > > > > > Also: > > > Singlet Oxygen is also produced in human cells as a by-product of > > > metabolism. Here, it can be harmful and cause cell damage, as it > > > acts as a Ôfree radical«. Yet Singlet Oxygen has a very short > > > lifespan, and returns to its ground state within a fraction of a > > > second. > > > In a humid atmosphere, its lifespan comprises only a few hundred > > > thousandths of a second. This means that no Singlet Oxygen can > leave > > > the equipment and, consequently, cannot harm any organismÉ. > > > ÉValkion imitates nature. They have constructed an activation > > > chamber, where an artificial light source acts together with a > high > > > efficiency heat and light resistant Ôphotosensitizer«. With an > > > air pump, a stream of activated air is created. This may then > be > > > inhaled, with or without the aid of an inhalation mask or nasal > > > cannula for research. Applications for research purposes vary. > The > > findings > > > show that moist air is essential; that is why every unit is > equipped > > > with a humidifier giving the activated air a humidity level of > at > > > least 85%(depending on the humidity and temperature of the > ambient > > air). > > > > > > --------From: http://www.rangeguide.net/valkion.htm > > > (Note: Called a few days ago for current pricing (approx $5,000. > + > > > shp. Over $1,000 more than BioTools-again fluctuates with the $. > > > He's an elder to some church and you would also have to join > their > > > church....NOT going to do that so if I'm able to swing this I'll > be > > > getting mine from BioTools.) > > > > > > > > > *--------Ukrainian website with links to medical trials in > Ukraine: > > > (This was some GREAT international medical studies: > > > Investigation of " Valkion Factors Effect on Energy Metabolism > and on > > > Oxygen Free Radical Generation " have been fulfilled at the > following > > > institution:) > > > http://www.tyoma.com.ua/investigation_2_2.html > > > > > > " Our company, situated in Ukraine, is scientific and selling > partner > > > of Polyvalk AB (Gothenburg, Sweden) à Valkion units producer. In > 1997 we > > > have Registered Valkion unit in Ukraine. Since that time we have > > > sold a lot of units to Medical Universities, clinics and private > people. > > > We have more than 100 reports from our partners on Pulmonology, > > > Gastroenterology, Traumatology, Dermatology, Radiology, > Nephrology > > > and urology, Obstetrics and gynaecology, Gerontology, Cardiology, > > > Hematology, Endocrinology, Neurology, Immunology, Infectology, > > > Surgery. > > > These researches were done in accordance to international terms > of > > > clinical investigations (2-3 groups with more than 20 patients > with > > > similar disease; one group treated with standard treatment, next > à > > > with Valkion therapy (or combined à Valkion therapy and standard > > > treatment) and sometimes (when it is possible) à third group à > > > uses placebo) and published in Ukrainian, European and Asian > > > scientific journals and as materials of different scientific > > conferences. > > > > > > > > > Swedish in vitro and animal studies: > > > Free Radical Biology and Medicine > > > Volume 27, Issues 11-12, December 1999, Pages 1203-1207 > > > > > > Harmful singlet oxygen can be helpful > > > > > > Lillemor Mattsson HultŽna, Marc Holmstršma and Bassam > > > SoussiCorresponding Author Contact Information, Wallenberg > > > Laboratory for Cardiovascular Research, University of Gšteborg, > > Sahlgrenska > > > University Hospital, Gšteborg, Sweden > > > > > > Highly reactive harmful singlet oxygen O2(1Î " g)can be helpful > while > > > relaxing to its triplet ground state O2(3Σg-). The energy > emitted > > > during this relaxation from the excited energy state is > discernable > > > at 634 nm. We report here on the effect of this energy as photon > > > illumination and as energy transfer in air on the production of > > > reactive oxygen species (ROS) by human monocytes, measured as > > > isoluminol-enhanced chemiluminescence. We demonstrate up to 60% > > > decrease in the secretion of ROS after 2-min illumination of the > > > monocytes stimulated with phorbol myristate acatate (PMA). The > > > results provide in vitro documentation of the utility of singlet > oxygen > > > energy in modifying cellular behaviour. > > > > > > Author Keywords: Human monocytes; Singlet oxygen; Reactive oxygen > > > species; Chemiluminescence; Oxidative stress; Photodynamic > therapy; > > > Free radicals > > > > > > > > > PMID: 10641712 full text: http://tinyurl.com/6gt4qv > > > Preservation of rat skeletal muscle energy metabolism by > illumination > > > > > > Ann LindgŒrd, Jonas Lundberg, Olivier Rakotonirainy, Elander > > > and Bassam Soussi. Department of Surgery and Plastic Surgery, > > > Bioenergetics Group, Wallenberg Laboratory, Sahlgrenska > University > > > Hospital, Gštenborg University, Gštenborg S-143-45, Sweden > > > > > > Skeletal muscle viability is crucially dependent on the tissue > > > levels of its high energy phosphates. In this study we > investigated the > > > effect of the preservation medium Perfadex and illumination with > Singlet > > > Oxygen Energy (SOE). Singlet oxygen can be produced > photochemically > > > by energy transfer from an excited photosensitizer. The energy > emitted > > > from singlet oxygen upon relaxation to its triplet state is > captured > > > as photons at 634 nm and is here referred to as SOE. Rat hind > limb > > > rectus femoris muscles were preserved for five hours at 22 ¡C in > > Perfadex, > > > saline, SOE illuminated Perfadex or SOE illuminated saline. > Extracts > > > of the muscles were analysed by 31P NMR. Data were analysed > using two- > > > way analysis of variance and are given as mean values (μmol/g > dry > > > weight) ± SEM. The ATP concentration was higher (p = 0.006) in > > > saline groups (4.52) compared with Perfadex groups (2.82). There > > > was no statistically significant difference in PCr between the > saline > > > groups (1.25) and Perfadex groups (0.82). However, there were > > higher (p = > > > 0.003) ATP in the SOE illuminated groups (4.61) compared with > the > > > non-illuminated groups (2.73). The PCr was also higher (p < > 0.0001) > > > in the SOE illuminated groups (1.89) compared with the non- > illuminated > > > groups (0.18). In conclusion, Perfadex in this experimental > model > > > was incapable of preserving the high energy phosphates in > skeletal > > > muscle during 5 hours of ischemia. Illumination with SOE at 634 > nm > > improved > > > the preservation potential, in terms of a positive effect on the > energy > > > status of the muscle cell. > > > > > > > > > PMID: 12672510 [PubMed - indexed for MEDLINE] > > > Transplant Proc. 2005 Jan-Feb;37(1):518-20. > > > > > > Singlet oxygen energy illumination during moderate cold ischemia > > > prolongs the survival of concordant hamster xeno-heart > transplants. > > > > > > Lukes DJ, Skogsberg U, Nilsson A, Lundgren A, Olausson M, > > > Soussi B. > > > Department of Surgery and Transplantation, Wallenberg > Laboratory for > > > Cardiovascular Research, Gšteborg, Sweden. > > > > > > INTRODUCTION: Singlet oxygen energy (SOE) is a potent inhibitor > > > of reactive oxygen species (ROS) in vitro and in vivo in certain > dose > > > ranges and can improve the levels of high-energy phosphates > (HEP) in > > > concordant hamster xeno-heart transplants. Some data indicate > that a > > > certain degree of cold ischemia (CI) might be beneficial to > > > xenotransplants. We investigated if SOE illumination of hamster > > > xeno-hearts during moderate cold ischemia (CI) improved graft > > > survival. > > > MATERIALS AND METHODS: Eighteen hearts from Golden Syrian > hamsters > > > (70 to 80 g) were subjected to 8 hours of CI in cold (+4 degrees > C) > > > saline solution (NaCL, 0.9%) before heterotopic cervical > > transplantation to > > > rats (220 g). Among the treatment group (n = 8), SOE was > > > produced by illuminating the hearts for 10 minutes every 30 > minutes with > > > photons at lambda 634 nm with the Oxylight equipment. Graft > function was > > > evaluated every 6 hours after transplantation with digital exam > > > until cessation of heart beats. RESULTS: The graft survival of > > > SOE-illuminated ischemic hamster xenografts was 2.34 +/- 0.56 > versus > > > 1.15 +/- 0.37 days in the control group (P < .05). All hearts > > > displayed immediate graft function versus 70% in the controls > (NS). > > > CONCLUSIONS: > > > SOE illumination at lambda 634 nm during moderate cold ischemia > (+4 > > > degrees C) can improve the survival of concordant hamster xeno- > heart > > > transplants. The exact mechanism(s) are currently unknown, but > the > > > effect might in part be exerted by a combination of reduced > > > production of ROS and increased oxidative phosphorylation. > > > > > > Publication Types: * Research Support, Non-U.S. Gov't > > > PMID: 15808696 [PubMed - indexed for MEDLINE] > > > > > > > > > Non-published research (study in Spanish): > > > > > > Therapy Valkion, its effect on non-traumatic joint pain. > > > > > > Dra. Flora Mar'a Hern‡ndez Pedraza, Dr. Orlando S‡nchez > > > Freire . Orlando Freire. Especialista de 1er Grado en > > > Medicina F'sica y Rehabilitaci—n.Diplomado en Fitoterapia > > > Cl'nicaÉ.Clinic Natural and Traditional Medicine. Santa Clara. > > > Santa Clara. Villa Clara. Villa Clara. > > > > > > We studied a total of 300 patients with non-traumatic joint pain > > > from the clinic of traditional medicine and natural Santa Clara > in the > > > first period from February 2000 until February 1, 2001. 3 > groups were > > > formed with 100 patients each: a control group with acupuncture > and two > > > tanks, one with phototherapy and another with VALKION therapy. > The > > average > > > number of days of treatment was 16 days, ending two months of > > > treatment patients treated with VALKION had no relapses and > decreased > > > consumption of drugs and therefore believe that this therapy > should > > be used in > > > patients with this condition because it is odourless and > harmless to > > > the patient as well as by its high therapeutic effectiveness. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2008 Report Share Posted July 24, 2008 Hi Gayatri, not Rita but we saw drK in April and he said he had seen very good results with it for his patients with autism. He didn't specify numbers and didn't go into details about benefits, but said repeatedly how good it could be for L, saying 'same or better than hbot, and safer...'. He is also supporting our application (we are applying to a children's charity to have Vakion financed, fingers xed!). Natasa x > > > > I have trying to compile info on the Valkion and Cold Laser > therapies so we would have a basic research document available. Since > Lorina has posted about the Valkion, thought I'd post up my latest > compilation of research. I can not thank Dr. Klinghardt, Dr Amy, Dr. > , Lorina, Limin, Natasa and many others as we worked > off-lists to gather info and research in our late night quests for > researching what would be best for our children. There is not a lot of > info out there right now on it's use with ASD but if you break down > some of the cellular level issues, it really supports this treatment. > I've researched, including some off-list e-mails with ASD moms happy > with it's use with their children. Hope this info will help someone > wanting to look into this further. The Valkion is expensive, but less > than what the HBOT would have run us, and we can use it from > home...which is a major plus for this busy family. > > Rita > > ----Forwarded ------ > > I am looking forward to hearing Dr. Klinghardt and other highly > regarded professionals demonstrate and talk about several things like > the Valkion an cold laser treatments at his upcoming Autism 2008 > conference. > > http://www.klinghardt.org/workshops.asp > > Thought I'd post some of the research our group has been putting > together to help anyone else that may be considering this. I > personally appreciated the international medical studies from > tyoma.com that I " * " below, especially noteworthy to our ASD children > > > > ------Dr. Klinghardt's - Copied from BioTools: > > " Energy Medicine for Autistic Children > > Practical Non-Biochemical Solutions, Specific Developments and > > Recommendations by Dietrich Klinghardt, MD,PhD > > 1. Increase Restorative Sleep > > The Problem: within 3 feet of the power supply in the bedroom wall - > > and within 1.6 miles of a cell phone transmitter - children have > > severely disturbed EEGs, decreased melatonin production and blocked > > activity of detoxification enzymes in the brain, gut, liver and > > kidneys > > The solution: the " Sleep Sanctuary " technology from BioTools > > evolved from the German teaching of the Institute of Baubiology. We > > have created an esthetic Faraday cage which decreases the EMF > > exposure of the child to one tenthousands– a silver coated mosquito > > net and grounding cloth > > Result: instantly normalization of the childs EEG, Heart Rate > > Variability and numerous hormonal, cytokine and other lab parameters. > > It improves blood and tissue oxygenation and tissue ph. Permanent > > behavioral and mental improvements in the child are dramatic and > > observed within days to weeks > > 2. Heal the brain > > The problem: The astrocytes are toxic. The blood brain barrier is > > stuck open. The mirror neurons – responsible for normal emotional and > > mental responses – are toxic and dysfunctional. There is no grooming > > of excessive neurons, etc. > > The Solutions: > > 1.The " Valkion " : a Swedish device which creates energized " singlet > > oxygen " for inhalation. This energized oxygen crosses the blood brain > > barrier rapidly and effectively. > > The problem: in ASD children with Lyme disease, mycoplasma, mold > > and viral infections the endothelium is lined with fibrin, delaying > > the delivery of oxygen to the tissues from 2 seconds to 5.4 minutes. > > The tissues are oxygen starved. This is the most effective device to > > deliver oxygen and energy to the brain, to the spinal chord and the > > kidneys. In our work with ASD children this is comparable with - or > > more effective - then HBOT. > > 2. Place the " Light Shield " over the brain. The visible > > monochromatic light stimulates brain function via the visceral- > > cutaneous reflex. The invisible IR light penetrates the skull and > > reaches 7 cm into the brain - reaching most of the higher cognitive > > areas easily. It increases bloodflow, venous and lymphatic drainage, > > metabolic activity of the brain cells, and activates the intrinsic > > detox mechanisms of the brain. The " light shield " also increases > > > medication uptake, a most important issue that has been overlooked > > by most. It also has a strong direct anti-viral effect and is > > phototactic – it strongly attracts NK cells into the illuminated > > areas. > > The result: the brain recovers faster, with less side effects. > > Appropriate treatments that did not seem to work before, can work now > > rapidly and profoundly. > > 3. Increase the Filtration Rate of the Kidneys > > The Problem: the basal membranes of the kidney become inflamed and > > swollen as soon as mercury, lead and other toxins are filtered during > > chelation therapy. The nephrons stay in an allergic, poorly > > filtrating state, as long as the metal mobilizing medication is given > > The solutions: > > 1. the BioTools " Light Shield " . By placing the device over the > > kidneys normal filtrating function resumes within less then an hour. > > The device should be used daily during active detox and during all > > crises. > > 2. The Swiss " Toxaway " electric foot bath uses an electrochemical > > process to stimulate the kidney and liver meridian at the feet to > > effectively increase toxin elimination activity of both organs. There > > is also direct active lymphatic excretion of toxins across the soles > > of the feet. This device is superior to other comparable instruments > > (the secret is in the electrodes) > > Result: dramatic shortening of the overall treatment time and > > improved success rate in stubborn cases. It minimizes the > > feared " healing crisis " after starting a chelation program > > 4. Improve phase-I and phase-II liver enzyme activity > > Problem: most of the ASD children have impaired liver enzyme > > function at different locations (p450, acetylation, sulfation, > > glutathione-S-transferase) > > Solution: the BioTools " Light Shield " . By placing the device over > > the kidneys ATP inside the cells increases significantly and the cell > > does its job more effectively. The light also turns on the cell > > organelles: the peroxisomes, the mitochondria, the Golgi apparatus, > > etc. It also enlarges the bile ducts, the arterioles and the lymph > > ducts in the liver by blocking the sympathetic nervous system and > > stimulating the parasympathetics. > > Result: in spite of numerous gene polymorphisms of the detox genes, > > the child starts eliminating neurotoxins and heavy metals at rates > > comparable or superior to normal children. " > > > > A google search of " Valkion " , " activated air " , " singlet oxygen " and > > " oxygen therapies " is a good thing when looking into this. > > -------Dr. from polyvalk.com > > http://www.subtleenergies.com/ormus/tw/singlet.htm > > > > -------Valkion patent page à description: > > http://tinyurl.com/5a8thb > > ÒÉEven though singlet oxygen quickly returns to oxygen in its ground > > state, by studying the effects of the described device, it can be > > demonstrated that a medium, liquid or gas, in which singlet oxygen > > has been formed, has a certain altered state, at least for a limited > > periodÉÓ > > > > ------Shorthand explanation from > > http://www.breathing.com/articles/oxygen-therapies.htm > > > > Oxidative Response: The cellular defense against Oxidative Stress is > > the Oxidative Response. The Oxidative Response System (or cell > > response > > system) protects against, and repairs, Oxidative Stress damage. This > > is > > accomplished mainly through enzyme and coenzyme production. The > > Oxidative Response is initiated by signal transduction sequences > > induced > > by singlet oxygen. Singlet oxygen is an activated oxygen species, but > > not a free radical. Signaling proteins then trigger the cell > > response. > > > > Cell response results include, but are not limited to: > > Protection against free radical damage > > Repair of damage caused by free radicals > > Improved Oxygen utilization > > Improved cell energy production > > Improved cell metabolism > > For optimal cell metabolism, a strong Oxidative Response and low > > Oxidative Stress are essential. > > > > Also: > > Singlet Oxygen is also produced in human cells as a by-product of > > metabolism. Here, it can be harmful and cause cell damage, as it > > acts as a Ôfree radical«. Yet Singlet Oxygen has a very short > > lifespan, and returns to its ground state within a fraction of a > > second. > > In a humid atmosphere, its lifespan comprises only a few hundred > > thousandths of a second. This means that no Singlet Oxygen can leave > > the equipment and, consequently, cannot harm any organismÉ. > > ÉValkion imitates nature. They have constructed an activation > > chamber, where an artificial light source acts together with a high > > efficiency heat and light resistant Ôphotosensitizer«. With an > > air pump, a stream of activated air is created. This may then be > > inhaled, with or without the aid of an inhalation mask or nasal > > cannula for research. Applications for research purposes vary. The > findings > > show that moist air is essential; that is why every unit is equipped > > with a humidifier giving the activated air a humidity level of at > > least 85%(depending on the humidity and temperature of the ambient > air). > > > > --------From: http://www.rangeguide.net/valkion.htm > > (Note: Called a few days ago for current pricing (approx $5,000. + > > shp. Over $1,000 more than BioTools-again fluctuates with the $. > > He's an elder to some church and you would also have to join their > > church....NOT going to do that so if I'm able to swing this I'll be > > getting mine from BioTools.) > > > > > > *--------Ukrainian website with links to medical trials in Ukraine: > > (This was some GREAT international medical studies: > > Investigation of " Valkion Factors Effect on Energy Metabolism and on > > Oxygen Free Radical Generation " have been fulfilled at the following > > institution:) > > http://www.tyoma.com.ua/investigation_2_2.html > > > > " Our company, situated in Ukraine, is scientific and selling partner > > of Polyvalk AB (Gothenburg, Sweden) à Valkion units producer. In 1997 we > > have Registered Valkion unit in Ukraine. Since that time we have > > sold a lot of units to Medical Universities, clinics and private people. > > We have more than 100 reports from our partners on Pulmonology, > > Gastroenterology, Traumatology, Dermatology, Radiology, Nephrology > > and urology, Obstetrics and gynaecology, Gerontology, Cardiology, > > Hematology, Endocrinology, Neurology, Immunology, Infectology, > > Surgery. > > These researches were done in accordance to international terms of > > clinical investigations (2-3 groups with more than 20 patients with > > similar disease; one group treated with standard treatment, next à > > with Valkion therapy (or combined à Valkion therapy and standard > > treatment) and sometimes (when it is possible) à third group à > > uses placebo) and published in Ukrainian, European and Asian > > scientific journals and as materials of different scientific > conferences. > > > > > > Swedish in vitro and animal studies: > > Free Radical Biology and Medicine > > Volume 27, Issues 11-12, December 1999, Pages 1203-1207 > > > > Harmful singlet oxygen can be helpful > > > > Lillemor Mattsson HultŽna, Marc Holmstršma and Bassam > > SoussiCorresponding Author Contact Information, Wallenberg > > Laboratory for Cardiovascular Research, University of Gšteborg, > Sahlgrenska > > University Hospital, Gšteborg, Sweden > > > > Highly reactive harmful singlet oxygen O2(1Î " g)can be helpful while > > relaxing to its triplet ground state O2(3Σg-). The energy emitted > > during this relaxation from the excited energy state is discernable > > at 634 nm. We report here on the effect of this energy as photon > > illumination and as energy transfer in air on the production of > > reactive oxygen species (ROS) by human monocytes, measured as > > isoluminol-enhanced chemiluminescence. We demonstrate up to 60% > > decrease in the secretion of ROS after 2-min illumination of the > > monocytes stimulated with phorbol myristate acatate (PMA). The > > results provide in vitro documentation of the utility of singlet oxygen > > energy in modifying cellular behaviour. > > > > Author Keywords: Human monocytes; Singlet oxygen; Reactive oxygen > > species; Chemiluminescence; Oxidative stress; Photodynamic therapy; > > Free radicals > > > > > > PMID: 10641712 full text: http://tinyurl.com/6gt4qv > > Preservation of rat skeletal muscle energy metabolism by illumination > > > > Ann LindgŒrd, Jonas Lundberg, Olivier Rakotonirainy, Elander > > and Bassam Soussi. Department of Surgery and Plastic Surgery, > > Bioenergetics Group, Wallenberg Laboratory, Sahlgrenska University > > Hospital, Gštenborg University, Gštenborg S-143-45, Sweden > > > > Skeletal muscle viability is crucially dependent on the tissue > > levels of its high energy phosphates. In this study we investigated the > > effect of the preservation medium Perfadex and illumination with Singlet > > Oxygen Energy (SOE). Singlet oxygen can be produced photochemically > > by energy transfer from an excited photosensitizer. The energy emitted > > from singlet oxygen upon relaxation to its triplet state is captured > > as photons at 634 nm and is here referred to as SOE. Rat hind limb > > rectus femoris muscles were preserved for five hours at 22 ¡C in > Perfadex, > > saline, SOE illuminated Perfadex or SOE illuminated saline. Extracts > > of the muscles were analysed by 31P NMR. Data were analysed using two- > > way analysis of variance and are given as mean values (μmol/g dry > > weight) ± SEM. The ATP concentration was higher (p = 0.006) in > > saline groups (4.52) compared with Perfadex groups (2.82). There > > was no statistically significant difference in PCr between the saline > > groups (1.25) and Perfadex groups (0.82). However, there were > higher (p = > > 0.003) ATP in the SOE illuminated groups (4.61) compared with the > > non-illuminated groups (2.73). The PCr was also higher (p < 0.0001) > > in the SOE illuminated groups (1.89) compared with the non-illuminated > > groups (0.18). In conclusion, Perfadex in this experimental model > > was incapable of preserving the high energy phosphates in skeletal > > muscle during 5 hours of ischemia. Illumination with SOE at 634 nm > improved > > the preservation potential, in terms of a positive effect on the energy > > status of the muscle cell. > > > > > > PMID: 12672510 [PubMed - indexed for MEDLINE] > > Transplant Proc. 2005 Jan-Feb;37(1):518-20. > > > > Singlet oxygen energy illumination during moderate cold ischemia > > prolongs the survival of concordant hamster xeno-heart transplants. > > > > Lukes DJ, Skogsberg U, Nilsson A, Lundgren A, Olausson M, > > Soussi B. > > Department of Surgery and Transplantation, Wallenberg Laboratory for > > Cardiovascular Research, Gšteborg, Sweden. > > > > INTRODUCTION: Singlet oxygen energy (SOE) is a potent inhibitor > > of reactive oxygen species (ROS) in vitro and in vivo in certain dose > > ranges and can improve the levels of high-energy phosphates (HEP) in > > concordant hamster xeno-heart transplants. Some data indicate that a > > certain degree of cold ischemia (CI) might be beneficial to > > xenotransplants. We investigated if SOE illumination of hamster > > xeno-hearts during moderate cold ischemia (CI) improved graft > > survival. > > MATERIALS AND METHODS: Eighteen hearts from Golden Syrian hamsters > > (70 to 80 g) were subjected to 8 hours of CI in cold (+4 degrees C) > > saline solution (NaCL, 0.9%) before heterotopic cervical > transplantation to > > rats (220 g). Among the treatment group (n = 8), SOE was > > produced by illuminating the hearts for 10 minutes every 30 minutes with > > photons at lambda 634 nm with the Oxylight equipment. Graft function was > > evaluated every 6 hours after transplantation with digital exam > > until cessation of heart beats. RESULTS: The graft survival of > > SOE-illuminated ischemic hamster xenografts was 2.34 +/- 0.56 versus > > 1.15 +/- 0.37 days in the control group (P < .05). All hearts > > displayed immediate graft function versus 70% in the controls (NS). > > CONCLUSIONS: > > SOE illumination at lambda 634 nm during moderate cold ischemia (+4 > > degrees C) can improve the survival of concordant hamster xeno-heart > > transplants. The exact mechanism(s) are currently unknown, but the > > effect might in part be exerted by a combination of reduced > > production of ROS and increased oxidative phosphorylation. > > > > Publication Types: * Research Support, Non-U.S. Gov't > > PMID: 15808696 [PubMed - indexed for MEDLINE] > > > > > > Non-published research (study in Spanish): > > > > Therapy Valkion, its effect on non-traumatic joint pain. > > > > Dra. Flora Mar'a Hern‡ndez Pedraza, Dr. Orlando S‡nchez > > Freire . Orlando Freire. Especialista de 1er Grado en > > Medicina F'sica y Rehabilitaci—n.Diplomado en Fitoterapia > > Cl'nicaÉ.Clinic Natural and Traditional Medicine. Santa Clara. > > Santa Clara. Villa Clara. Villa Clara. > > > > We studied a total of 300 patients with non-traumatic joint pain > > from the clinic of traditional medicine and natural Santa Clara in the > > first period from February 2000 until February 1, 2001. 3 groups were > > formed with 100 patients each: a control group with acupuncture and two > > tanks, one with phototherapy and another with VALKION therapy. The > average > > number of days of treatment was 16 days, ending two months of > > treatment patients treated with VALKION had no relapses and decreased > > consumption of drugs and therefore believe that this therapy should > be used in > > patients with this condition because it is odourless and harmless to > > the patient as well as by its high therapeutic effectiveness. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2008 Report Share Posted July 24, 2008 Thanks Natasa, and Rita and Lorina. Those accounts sound impressive. I hope you continue to see good things from it. Sorry if I missed it but is this in the 3K to 5K range costwise? Thanks Gayatri > > > > > > > > I have trying to compile info on the Valkion and Cold Laser > > > therapies so we would have a basic research document available. > > Since > > > Lorina has posted about the Valkion, thought I'd post up my latest > > > compilation of research. I can not thank Dr. Klinghardt, Dr Amy, > > Dr. > > > , Lorina, Limin, Natasa and many others as we worked > > > off-lists to gather info and research in our late night quests for > > > researching what would be best for our children. There is not a > > lot of > > > info out there right now on it's use with ASD but if you break > down > > > some of the cellular level issues, it really supports this > > treatment. > > > I've researched, including some off-list e-mails with ASD moms > > happy > > > with it's use with their children. Hope this info will help > someone > > > wanting to look into this further. The Valkion is expensive, but > > less > > > than what the HBOT would have run us, and we can use it from > > > home...which is a major plus for this busy family. > > > > Rita > > > > ----Forwarded ------ > > > > I am looking forward to hearing Dr. Klinghardt and other highly > > > regarded professionals demonstrate and talk about several things > > like > > > the Valkion an cold laser treatments at his upcoming Autism 2008 > > > conference. > > > > http://www.klinghardt.org/workshops.asp > > > > Thought I'd post some of the research our group has been putting > > > together to help anyone else that may be considering this. I > > > personally appreciated the international medical studies from > > > tyoma.com that I " * " below, especially noteworthy to our ASD > > children > > > > > > > > ------Dr. Klinghardt's - Copied from BioTools: > > > > " Energy Medicine for Autistic Children > > > > Practical Non-Biochemical Solutions, Specific Developments and > > > > Recommendations by Dietrich Klinghardt, MD,PhD > > > > 1. Increase Restorative Sleep > > > > The Problem: within 3 feet of the power supply in the bedroom > > wall - > > > > and within 1.6 miles of a cell phone transmitter - children have > > > > severely disturbed EEGs, decreased melatonin production and > > blocked > > > > activity of detoxification enzymes in the brain, gut, liver and > > > > kidneys > > > > The solution: the " Sleep Sanctuary " technology from BioTools > > > > evolved from the German teaching of the Institute of > Baubiology. > > We > > > > have created an esthetic Faraday cage which decreases the EMF > > > > exposure of the child to one tenthousands– a silver coated > > mosquito > > > > net and grounding cloth > > > > Result: instantly normalization of the childs EEG, Heart Rate > > > > Variability and numerous hormonal, cytokine and other lab > > parameters. > > > > It improves blood and tissue oxygenation and tissue ph. > Permanent > > > > behavioral and mental improvements in the child are dramatic and > > > > observed within days to weeks > > > > 2. Heal the brain > > > > The problem: The astrocytes are toxic. The blood brain barrier > > is > > > > stuck open. The mirror neurons – responsible for normal > > emotional and > > > > mental responses – are toxic and dysfunctional. There is no > > grooming > > > > of excessive neurons, etc. > > > > The Solutions: > > > > 1.The " Valkion " : a Swedish device which creates > > energized " singlet > > > > oxygen " for inhalation. This energized oxygen crosses the blood > > brain > > > > barrier rapidly and effectively. > > > > The problem: in ASD children with Lyme disease, mycoplasma, > mold > > > > and viral infections the endothelium is lined with fibrin, > > delaying > > > > the delivery of oxygen to the tissues from 2 seconds to 5.4 > > minutes. > > > > The tissues are oxygen starved. This is the most effective > > device to > > > > deliver oxygen and energy to the brain, to the spinal chord and > > the > > > > kidneys. In our work with ASD children this is comparable with - > > > or > > > > more effective - then HBOT. > > > > 2. Place the " Light Shield " over the brain. The visible > > > > monochromatic light stimulates brain function via the visceral- > > > > cutaneous reflex. The invisible IR light penetrates the skull > and > > > > reaches 7 cm into the brain - reaching most of the higher > > cognitive > > > > areas easily. It increases bloodflow, venous and lymphatic > > drainage, > > > > metabolic activity of the brain cells, and activates the > > intrinsic > > > > detox mechanisms of the brain. The " light shield " also increases > > > > > medication uptake, a most important issue that has been > > overlooked > > > > by most. It also has a strong direct anti-viral effect and is > > > > phototactic – it strongly attracts NK cells into the illuminated > > > > areas. > > > > The result: the brain recovers faster, with less side effects. > > > > Appropriate treatments that did not seem to work before, can > > work now > > > > rapidly and profoundly. > > > > 3. Increase the Filtration Rate of the Kidneys > > > > The Problem: the basal membranes of the kidney become inflamed > > and > > > > swollen as soon as mercury, lead and other toxins are filtered > > during > > > > chelation therapy. The nephrons stay in an allergic, poorly > > > > filtrating state, as long as the metal mobilizing medication is > > given > > > > The solutions: > > > > 1. the BioTools " Light Shield " . By placing the device over the > > > > kidneys normal filtrating function resumes within less then an > > hour. > > > > The device should be used daily during active detox and during > > all > > > > crises. > > > > 2. The Swiss " Toxaway " electric foot bath uses an > > electrochemical > > > > process to stimulate the kidney and liver meridian at the feet > to > > > > effectively increase toxin elimination activity of both organs. > > There > > > > is also direct active lymphatic excretion of toxins across the > > soles > > > > of the feet. This device is superior to other comparable > > instruments > > > > (the secret is in the electrodes) > > > > Result: dramatic shortening of the overall treatment time and > > > > improved success rate in stubborn cases. It minimizes the > > > > feared " healing crisis " after starting a chelation program > > > > 4. Improve phase-I and phase-II liver enzyme activity > > > > Problem: most of the ASD children have impaired liver enzyme > > > > function at different locations (p450, acetylation, sulfation, > > > > glutathione-S-transferase) > > > > Solution: the BioTools " Light Shield " . By placing the device > > over > > > > the kidneys ATP inside the cells increases significantly and > the > > cell > > > > does its job more effectively. The light also turns on the cell > > > > organelles: the peroxisomes, the mitochondria, the Golgi > > apparatus, > > > > etc. It also enlarges the bile ducts, the arterioles and the > > lymph > > > > ducts in the liver by blocking the sympathetic nervous system > and > > > > stimulating the parasympathetics. > > > > Result: in spite of numerous gene polymorphisms of the detox > > genes, > > > > the child starts eliminating neurotoxins and heavy metals at > > rates > > > > comparable or superior to normal children. " > > > > > > > > A google search of " Valkion " , " activated air " , " singlet oxygen " > > and > > > > " oxygen therapies " is a good thing when looking into this. > > > > -------Dr. from polyvalk.com > > > > http://www.subtleenergies.com/ormus/tw/singlet.htm > > > > > > > > -------Valkion patent page à description: > > > > http://tinyurl.com/5a8thb > > > > ÒÉEven though singlet oxygen quickly returns to oxygen in its > > ground > > > > state, by studying the effects of the described device, it can > be > > > > demonstrated that a medium, liquid or gas, in which singlet > > oxygen > > > > has been formed, has a certain altered state, at least for a > > limited > > > > periodÉÓ > > > > > > > > ------Shorthand explanation from > > > > http://www.breathing.com/articles/oxygen-therapies.htm > > > > > > > > Oxidative Response: The cellular defense against Oxidative > > Stress is > > > > the Oxidative Response. The Oxidative Response System (or cell > > > > response > > > > system) protects against, and repairs, Oxidative Stress damage. > > This > > > > is > > > > accomplished mainly through enzyme and coenzyme production. The > > > > Oxidative Response is initiated by signal transduction sequences > > > > induced > > > > by singlet oxygen. Singlet oxygen is an activated oxygen > > species, but > > > > not a free radical. Signaling proteins then trigger the cell > > > > response. > > > > > > > > Cell response results include, but are not limited to: > > > > Protection against free radical damage > > > > Repair of damage caused by free radicals > > > > Improved Oxygen utilization > > > > Improved cell energy production > > > > Improved cell metabolism > > > > For optimal cell metabolism, a strong Oxidative Response and low > > > > Oxidative Stress are essential. > > > > > > > > Also: > > > > Singlet Oxygen is also produced in human cells as a by-product > of > > > > metabolism. Here, it can be harmful and cause cell damage, as > it > > > > acts as a Ôfree radical«. Yet Singlet Oxygen has a very short > > > > lifespan, and returns to its ground state within a fraction of a > > > > second. > > > > In a humid atmosphere, its lifespan comprises only a few hundred > > > > thousandths of a second. This means that no Singlet Oxygen can > > leave > > > > the equipment and, consequently, cannot harm any organismÉ. > > > > ÉValkion imitates nature. They have constructed an activation > > > > chamber, where an artificial light source acts together with a > > high > > > > efficiency heat and light resistant Ôphotosensitizer«. With an > > > > air pump, a stream of activated air is created. This may then > > be > > > > inhaled, with or without the aid of an inhalation mask or nasal > > > > cannula for research. Applications for research purposes > vary. > > The > > > findings > > > > show that moist air is essential; that is why every unit is > > equipped > > > > with a humidifier giving the activated air a humidity level of > > at > > > > least 85%(depending on the humidity and temperature of the > > ambient > > > air). > > > > > > > > --------From: http://www.rangeguide.net/valkion.htm > > > > (Note: Called a few days ago for current pricing (approx > $5,000. > > + > > > > shp. Over $1,000 more than BioTools-again fluctuates with the $. > > > > He's an elder to some church and you would also have to join > > their > > > > church....NOT going to do that so if I'm able to swing this > I'll > > be > > > > getting mine from BioTools.) > > > > > > > > > > > > *--------Ukrainian website with links to medical trials in > > Ukraine: > > > > (This was some GREAT international medical studies: > > > > Investigation of " Valkion Factors Effect on Energy Metabolism > > and on > > > > Oxygen Free Radical Generation " have been fulfilled at the > > following > > > > institution:) > > > > http://www.tyoma.com.ua/investigation_2_2.html > > > > > > > > " Our company, situated in Ukraine, is scientific and selling > > partner > > > > of Polyvalk AB (Gothenburg, Sweden) à Valkion units producer. > In > > 1997 we > > > > have Registered Valkion unit in Ukraine. Since that time we have > > > > sold a lot of units to Medical Universities, clinics and > private > > people. > > > > We have more than 100 reports from our partners on Pulmonology, > > > > Gastroenterology, Traumatology, Dermatology, Radiology, > > Nephrology > > > > and urology, Obstetrics and gynaecology, Gerontology, > Cardiology, > > > > Hematology, Endocrinology, Neurology, Immunology, Infectology, > > > > Surgery. > > > > These researches were done in accordance to international terms > > of > > > > clinical investigations (2-3 groups with more than 20 patients > > with > > > > similar disease; one group treated with standard treatment, > next > > à > > > > with Valkion therapy (or combined à Valkion therapy and > standard > > > > treatment) and sometimes (when it is possible) à third group à > > > > uses placebo) and published in Ukrainian, European and Asian > > > > scientific journals and as materials of different scientific > > > conferences. > > > > > > > > > > > > Swedish in vitro and animal studies: > > > > Free Radical Biology and Medicine > > > > Volume 27, Issues 11-12, December 1999, Pages 1203-1207 > > > > > > > > Harmful singlet oxygen can be helpful > > > > > > > > Lillemor Mattsson HultŽna, Marc Holmstršma and Bassam > > > > SoussiCorresponding Author Contact Information, Wallenberg > > > > Laboratory for Cardiovascular Research, University of Gšteborg, > > > Sahlgrenska > > > > University Hospital, Gšteborg, Sweden > > > > > > > > Highly reactive harmful singlet oxygen O2(1Î " g)can be helpful > > while > > > > relaxing to its triplet ground state O2(3Σg-). The energy > > emitted > > > > during this relaxation from the excited energy state is > > discernable > > > > at 634 nm. We report here on the effect of this energy as photon > > > > illumination and as energy transfer in air on the production of > > > > reactive oxygen species (ROS) by human monocytes, measured as > > > > isoluminol-enhanced chemiluminescence. We demonstrate up to 60% > > > > decrease in the secretion of ROS after 2-min illumination of the > > > > monocytes stimulated with phorbol myristate acatate (PMA). The > > > > results provide in vitro documentation of the utility of > singlet > > oxygen > > > > energy in modifying cellular behaviour. > > > > > > > > Author Keywords: Human monocytes; Singlet oxygen; Reactive > oxygen > > > > species; Chemiluminescence; Oxidative stress; Photodynamic > > therapy; > > > > Free radicals > > > > > > > > > > > > PMID: 10641712 full text: http://tinyurl.com/6gt4qv > > > > Preservation of rat skeletal muscle energy metabolism by > > illumination > > > > > > > > Ann LindgŒrd, Jonas Lundberg, Olivier Rakotonirainy, > Elander > > > > and Bassam Soussi. Department of Surgery and Plastic Surgery, > > > > Bioenergetics Group, Wallenberg Laboratory, Sahlgrenska > > University > > > > Hospital, Gštenborg University, Gštenborg S-143-45, Sweden > > > > > > > > Skeletal muscle viability is crucially dependent on the tissue > > > > levels of its high energy phosphates. In this study we > > investigated the > > > > effect of the preservation medium Perfadex and illumination > with > > Singlet > > > > Oxygen Energy (SOE). Singlet oxygen can be produced > > photochemically > > > > by energy transfer from an excited photosensitizer. The energy > > emitted > > > > from singlet oxygen upon relaxation to its triplet state is > > captured > > > > as photons at 634 nm and is here referred to as SOE. Rat hind > > limb > > > > rectus femoris muscles were preserved for five hours at 22 ¡C in > > > Perfadex, > > > > saline, SOE illuminated Perfadex or SOE illuminated saline. > > Extracts > > > > of the muscles were analysed by 31P NMR. Data were analysed > > using two- > > > > way analysis of variance and are given as mean values (μmol/g > > dry > > > > weight) ± SEM. The ATP concentration was higher (p = 0.006) in > > > > saline groups (4.52) compared with Perfadex groups (2.82). > There > > > > was no statistically significant difference in PCr between the > > saline > > > > groups (1.25) and Perfadex groups (0.82). However, there were > > > higher (p = > > > > 0.003) ATP in the SOE illuminated groups (4.61) compared with > > the > > > > non-illuminated groups (2.73). The PCr was also higher (p < > > 0.0001) > > > > in the SOE illuminated groups (1.89) compared with the non- > > illuminated > > > > groups (0.18). In conclusion, Perfadex in this experimental > > model > > > > was incapable of preserving the high energy phosphates in > > skeletal > > > > muscle during 5 hours of ischemia. Illumination with SOE at 634 > > nm > > > improved > > > > the preservation potential, in terms of a positive effect on > the > > energy > > > > status of the muscle cell. > > > > > > > > > > > > PMID: 12672510 [PubMed - indexed for MEDLINE] > > > > Transplant Proc. 2005 Jan-Feb;37(1):518-20. > > > > > > > > Singlet oxygen energy illumination during moderate cold ischemia > > > > prolongs the survival of concordant hamster xeno-heart > > transplants. > > > > > > > > Lukes DJ, Skogsberg U, Nilsson A, Lundgren A, Olausson M, > > > > Soussi B. > > > > Department of Surgery and Transplantation, Wallenberg > > Laboratory for > > > > Cardiovascular Research, Gšteborg, Sweden. > > > > > > > > INTRODUCTION: Singlet oxygen energy (SOE) is a potent inhibitor > > > > of reactive oxygen species (ROS) in vitro and in vivo in > certain > > dose > > > > ranges and can improve the levels of high-energy phosphates > > (HEP) in > > > > concordant hamster xeno-heart transplants. Some data indicate > > that a > > > > certain degree of cold ischemia (CI) might be beneficial to > > > > xenotransplants. We investigated if SOE illumination of hamster > > > > xeno-hearts during moderate cold ischemia (CI) improved graft > > > > survival. > > > > MATERIALS AND METHODS: Eighteen hearts from Golden Syrian > > hamsters > > > > (70 to 80 g) were subjected to 8 hours of CI in cold (+4 > degrees > > C) > > > > saline solution (NaCL, 0.9%) before heterotopic cervical > > > transplantation to > > > > rats (220 g). Among the treatment group (n = 8), SOE was > > > > produced by illuminating the hearts for 10 minutes every 30 > > minutes with > > > > photons at lambda 634 nm with the Oxylight equipment. Graft > > function was > > > > evaluated every 6 hours after transplantation with digital exam > > > > until cessation of heart beats. RESULTS: The graft survival of > > > > SOE-illuminated ischemic hamster xenografts was 2.34 +/- 0.56 > > versus > > > > 1.15 +/- 0.37 days in the control group (P < .05). All hearts > > > > displayed immediate graft function versus 70% in the controls > > (NS). > > > > CONCLUSIONS: > > > > SOE illumination at lambda 634 nm during moderate cold > ischemia > > (+4 > > > > degrees C) can improve the survival of concordant hamster xeno- > > heart > > > > transplants. The exact mechanism(s) are currently unknown, but > > the > > > > effect might in part be exerted by a combination of reduced > > > > production of ROS and increased oxidative phosphorylation. > > > > > > > > Publication Types: * Research Support, Non-U.S. Gov't > > > > PMID: 15808696 [PubMed - indexed for MEDLINE] > > > > > > > > > > > > Non-published research (study in Spanish): > > > > > > > > Therapy Valkion, its effect on non-traumatic joint pain. > > > > > > > > Dra. Flora Mar'a Hern‡ndez Pedraza, Dr. Orlando S‡nchez > > > > Freire . Orlando Freire. Especialista de 1er Grado en > > > > Medicina F'sica y Rehabilitaci—n.Diplomado en Fitoterapia > > > > Cl'nicaÉ.Clinic Natural and Traditional Medicine. Santa Clara. > > > > Santa Clara. Villa Clara. Villa Clara. > > > > > > > > We studied a total of 300 patients with non-traumatic joint pain > > > > from the clinic of traditional medicine and natural Santa Clara > > in the > > > > first period from February 2000 until February 1, 2001. 3 > > groups were > > > > formed with 100 patients each: a control group with acupuncture > > and two > > > > tanks, one with phototherapy and another with VALKION therapy. > > The > > > average > > > > number of days of treatment was 16 days, ending two months of > > > > treatment patients treated with VALKION had no relapses and > > decreased > > > > consumption of drugs and therefore believe that this therapy > > should > > > be used in > > > > patients with this condition because it is odourless and > > harmless to > > > > the patient as well as by its high therapeutic effectiveness. > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2008 Report Share Posted July 24, 2008 Gayatri, Yep....it hurts! 4K. Since we're in WA we also had to add 9.9% sales tax too because they are head-quartered here (didn't cut the shipping though because it ships out of CO. We ended up financing ours...hated to do it with our limited income...but we really felt he needed it. In the long run it's substantially less than the HBOT and the whole family can use it. We negotiated a group discount, and if you do decide to get it, ask for the ASD discount...at least they give $100 off for ASD kids. They said the price was going to increase with the dropping $. We had been reviewing and negotiating this for months, including trying to get ASD studies with both the Eng3 and Valkion with the help of our doctors...no go...we decided to not waste anymore time and just bite the bullet. I really hope Natasa gets her funding!! Rita > > > > > > > > > > I have trying to compile info on the Valkion and Cold Laser > > > > therapies so we would have a basic research document available. > > > Since > > > > Lorina has posted about the Valkion, thought I'd post up my latest > > > > compilation of research. I can not thank Dr. Klinghardt, Dr Amy, > > > Dr. > > > > , Lorina, Limin, Natasa and many others as we worked > > > > off-lists to gather info and research in our late night quests for > > > > researching what would be best for our children. There is not a > > > lot of > > > > info out there right now on it's use with ASD but if you break > > down > > > > some of the cellular level issues, it really supports this > > > treatment. > > > > I've researched, including some off-list e-mails with ASD moms > > > happy > > > > with it's use with their children. Hope this info will help > > someone > > > > wanting to look into this further. The Valkion is expensive, but > > > less > > > > than what the HBOT would have run us, and we can use it from > > > > home...which is a major plus for this busy family. > > > > > Rita > > > > > ----Forwarded ------ > > > > > I am looking forward to hearing Dr. Klinghardt and other highly > > > > regarded professionals demonstrate and talk about several things > > > like > > > > the Valkion an cold laser treatments at his upcoming Autism 2008 > > > > conference. > > > > > http://www.klinghardt.org/workshops.asp > > > > > Thought I'd post some of the research our group has been putting > > > > together to help anyone else that may be considering this. I > > > > personally appreciated the international medical studies from > > > > tyoma.com that I " * " below, especially noteworthy to our ASD > > > children > > > > > > > > > > ------Dr. Klinghardt's - Copied from BioTools: > > > > > " Energy Medicine for Autistic Children > > > > > Practical Non-Biochemical Solutions, Specific Developments and > > > > > Recommendations by Dietrich Klinghardt, MD,PhD > > > > > 1. Increase Restorative Sleep > > > > > The Problem: within 3 feet of the power supply in the bedroom > > > wall - > > > > > and within 1.6 miles of a cell phone transmitter - children have > > > > > severely disturbed EEGs, decreased melatonin production and > > > blocked > > > > > activity of detoxification enzymes in the brain, gut, liver and > > > > > kidneys > > > > > The solution: the " Sleep Sanctuary " technology from BioTools > > > > > evolved from the German teaching of the Institute of > > Baubiology. > > > We > > > > > have created an esthetic Faraday cage which decreases the EMF > > > > > exposure of the child to one tenthousands– a silver coated > > > mosquito > > > > > net and grounding cloth > > > > > Result: instantly normalization of the childs EEG, Heart Rate > > > > > Variability and numerous hormonal, cytokine and other lab > > > parameters. > > > > > It improves blood and tissue oxygenation and tissue ph. > > Permanent > > > > > behavioral and mental improvements in the child are dramatic and > > > > > observed within days to weeks > > > > > 2. Heal the brain > > > > > The problem: The astrocytes are toxic. The blood brain barrier > > > is > > > > > stuck open. The mirror neurons – responsible for normal > > > emotional and > > > > > mental responses – are toxic and dysfunctional. There is no > > > grooming > > > > > of excessive neurons, etc. > > > > > The Solutions: > > > > > 1.The " Valkion " : a Swedish device which creates > > > energized " singlet > > > > > oxygen " for inhalation. This energized oxygen crosses the blood > > > brain > > > > > barrier rapidly and effectively. > > > > > The problem: in ASD children with Lyme disease, mycoplasma, > > mold > > > > > and viral infections the endothelium is lined with fibrin, > > > delaying > > > > > the delivery of oxygen to the tissues from 2 seconds to 5.4 > > > minutes. > > > > > The tissues are oxygen starved. This is the most effective > > > device to > > > > > deliver oxygen and energy to the brain, to the spinal chord and > > > the > > > > > kidneys. In our work with ASD children this is comparable with - > > > > > or > > > > > more effective - then HBOT. > > > > > 2. Place the " Light Shield " over the brain. The visible > > > > > monochromatic light stimulates brain function via the visceral- > > > > > cutaneous reflex. The invisible IR light penetrates the skull > > and > > > > > reaches 7 cm into the brain - reaching most of the higher > > > cognitive > > > > > areas easily. It increases bloodflow, venous and lymphatic > > > drainage, > > > > > metabolic activity of the brain cells, and activates the > > > intrinsic > > > > > detox mechanisms of the brain. The " light shield " also increases > > > > > > medication uptake, a most important issue that has been > > > overlooked > > > > > by most. It also has a strong direct anti-viral effect and is > > > > > phototactic – it strongly attracts NK cells into the illuminated > > > > > areas. > > > > > The result: the brain recovers faster, with less side effects. > > > > > Appropriate treatments that did not seem to work before, can > > > work now > > > > > rapidly and profoundly. > > > > > 3. Increase the Filtration Rate of the Kidneys > > > > > The Problem: the basal membranes of the kidney become inflamed > > > and > > > > > swollen as soon as mercury, lead and other toxins are filtered > > > during > > > > > chelation therapy. The nephrons stay in an allergic, poorly > > > > > filtrating state, as long as the metal mobilizing medication is > > > given > > > > > The solutions: > > > > > 1. the BioTools " Light Shield " . By placing the device over the > > > > > kidneys normal filtrating function resumes within less then an > > > hour. > > > > > The device should be used daily during active detox and during > > > all > > > > > crises. > > > > > 2. The Swiss " Toxaway " electric foot bath uses an > > > electrochemical > > > > > process to stimulate the kidney and liver meridian at the feet > > to > > > > > effectively increase toxin elimination activity of both organs. > > > There > > > > > is also direct active lymphatic excretion of toxins across the > > > soles > > > > > of the feet. This device is superior to other comparable > > > instruments > > > > > (the secret is in the electrodes) > > > > > Result: dramatic shortening of the overall treatment time and > > > > > improved success rate in stubborn cases. It minimizes the > > > > > feared " healing crisis " after starting a chelation program > > > > > 4. Improve phase-I and phase-II liver enzyme activity > > > > > Problem: most of the ASD children have impaired liver enzyme > > > > > function at different locations (p450, acetylation, sulfation, > > > > > glutathione-S-transferase) > > > > > Solution: the BioTools " Light Shield " . By placing the device > > > over > > > > > the kidneys ATP inside the cells increases significantly and > > the > > > cell > > > > > does its job more effectively. The light also turns on the cell > > > > > organelles: the peroxisomes, the mitochondria, the Golgi > > > apparatus, > > > > > etc. It also enlarges the bile ducts, the arterioles and the > > > lymph > > > > > ducts in the liver by blocking the sympathetic nervous system > > and > > > > > stimulating the parasympathetics. > > > > > Result: in spite of numerous gene polymorphisms of the detox > > > genes, > > > > > the child starts eliminating neurotoxins and heavy metals at > > > rates > > > > > comparable or superior to normal children. " > > > > > > > > > > A google search of " Valkion " , " activated air " , " singlet oxygen " > > > and > > > > > " oxygen therapies " is a good thing when looking into this. > > > > > -------Dr. from polyvalk.com > > > > > http://www.subtleenergies.com/ormus/tw/singlet.htm > > > > > > > > > > -------Valkion patent page à description: > > > > > http://tinyurl.com/5a8thb > > > > > ÒÉEven though singlet oxygen quickly returns to oxygen in its > > > ground > > > > > state, by studying the effects of the described device, it can > > be > > > > > demonstrated that a medium, liquid or gas, in which singlet > > > oxygen > > > > > has been formed, has a certain altered state, at least for a > > > limited > > > > > periodÉÓ > > > > > > > > > > ------Shorthand explanation from > > > > > http://www.breathing.com/articles/oxygen-therapies.htm > > > > > > > > > > Oxidative Response: The cellular defense against Oxidative > > > Stress is > > > > > the Oxidative Response. The Oxidative Response System (or cell > > > > > response > > > > > system) protects against, and repairs, Oxidative Stress damage. > > > This > > > > > is > > > > > accomplished mainly through enzyme and coenzyme production. The > > > > > Oxidative Response is initiated by signal transduction sequences > > > > > induced > > > > > by singlet oxygen. Singlet oxygen is an activated oxygen > > > species, but > > > > > not a free radical. Signaling proteins then trigger the cell > > > > > response. > > > > > > > > > > Cell response results include, but are not limited to: > > > > > Protection against free radical damage > > > > > Repair of damage caused by free radicals > > > > > Improved Oxygen utilization > > > > > Improved cell energy production > > > > > Improved cell metabolism > > > > > For optimal cell metabolism, a strong Oxidative Response and low > > > > > Oxidative Stress are essential. > > > > > > > > > > Also: > > > > > Singlet Oxygen is also produced in human cells as a by- product > > of > > > > > metabolism. Here, it can be harmful and cause cell damage, as > > it > > > > > acts as a Ôfree radical«. Yet Singlet Oxygen has a very short > > > > > lifespan, and returns to its ground state within a fraction of a > > > > > second. > > > > > In a humid atmosphere, its lifespan comprises only a few hundred > > > > > thousandths of a second. This means that no Singlet Oxygen can > > > leave > > > > > the equipment and, consequently, cannot harm any organismÉ. > > > > > ÉValkion imitates nature. They have constructed an activation > > > > > chamber, where an artificial light source acts together with a > > > high > > > > > efficiency heat and light resistant Ôphotosensitizer«. With an > > > > > air pump, a stream of activated air is created. This may then > > > be > > > > > inhaled, with or without the aid of an inhalation mask or nasal > > > > > cannula for research. Applications for research purposes > > vary. > > > The > > > > findings > > > > > show that moist air is essential; that is why every unit is > > > equipped > > > > > with a humidifier giving the activated air a humidity level of > > > at > > > > > least 85%(depending on the humidity and temperature of the > > > ambient > > > > air). > > > > > > > > > > --------From: http://www.rangeguide.net/valkion.htm > > > > > (Note: Called a few days ago for current pricing (approx > > $5,000. > > > + > > > > > shp. Over $1,000 more than BioTools-again fluctuates with the $. > > > > > He's an elder to some church and you would also have to join > > > their > > > > > church....NOT going to do that so if I'm able to swing this > > I'll > > > be > > > > > getting mine from BioTools.) > > > > > > > > > > > > > > > *--------Ukrainian website with links to medical trials in > > > Ukraine: > > > > > (This was some GREAT international medical studies: > > > > > Investigation of " Valkion Factors Effect on Energy Metabolism > > > and on > > > > > Oxygen Free Radical Generation " have been fulfilled at the > > > following > > > > > institution:) > > > > > http://www.tyoma.com.ua/investigation_2_2.html > > > > > > > > > > " Our company, situated in Ukraine, is scientific and selling > > > partner > > > > > of Polyvalk AB (Gothenburg, Sweden) à Valkion units producer. > > In > > > 1997 we > > > > > have Registered Valkion unit in Ukraine. Since that time we have > > > > > sold a lot of units to Medical Universities, clinics and > > private > > > people. > > > > > We have more than 100 reports from our partners on Pulmonology, > > > > > Gastroenterology, Traumatology, Dermatology, Radiology, > > > Nephrology > > > > > and urology, Obstetrics and gynaecology, Gerontology, > > Cardiology, > > > > > Hematology, Endocrinology, Neurology, Immunology, Infectology, > > > > > Surgery. > > > > > These researches were done in accordance to international terms > > > of > > > > > clinical investigations (2-3 groups with more than 20 patients > > > with > > > > > similar disease; one group treated with standard treatment, > > next > > > à > > > > > with Valkion therapy (or combined à Valkion therapy and > > standard > > > > > treatment) and sometimes (when it is possible) à third group à > > > > > uses placebo) and published in Ukrainian, European and Asian > > > > > scientific journals and as materials of different scientific > > > > conferences. > > > > > > > > > > > > > > > Swedish in vitro and animal studies: > > > > > Free Radical Biology and Medicine > > > > > Volume 27, Issues 11-12, December 1999, Pages 1203-1207 > > > > > > > > > > Harmful singlet oxygen can be helpful > > > > > > > > > > Lillemor Mattsson HultŽna, Marc Holmstršma and Bassam > > > > > SoussiCorresponding Author Contact Information, Wallenberg > > > > > Laboratory for Cardiovascular Research, University of Gšteborg, > > > > Sahlgrenska > > > > > University Hospital, Gšteborg, Sweden > > > > > > > > > > Highly reactive harmful singlet oxygen O2(1Î " g)can be helpful > > > while > > > > > relaxing to its triplet ground state O2(3Σg-). The energy > > > emitted > > > > > during this relaxation from the excited energy state is > > > discernable > > > > > at 634 nm. We report here on the effect of this energy as photon > > > > > illumination and as energy transfer in air on the production of > > > > > reactive oxygen species (ROS) by human monocytes, measured as > > > > > isoluminol-enhanced chemiluminescence. We demonstrate up to 60% > > > > > decrease in the secretion of ROS after 2-min illumination of the > > > > > monocytes stimulated with phorbol myristate acatate (PMA). The > > > > > results provide in vitro documentation of the utility of > > singlet > > > oxygen > > > > > energy in modifying cellular behaviour. > > > > > > > > > > Author Keywords: Human monocytes; Singlet oxygen; Reactive > > oxygen > > > > > species; Chemiluminescence; Oxidative stress; Photodynamic > > > therapy; > > > > > Free radicals > > > > > > > > > > > > > > > PMID: 10641712 full text: http://tinyurl.com/6gt4qv > > > > > Preservation of rat skeletal muscle energy metabolism by > > > illumination > > > > > > > > > > Ann LindgŒrd, Jonas Lundberg, Olivier Rakotonirainy, > > Elander > > > > > and Bassam Soussi. Department of Surgery and Plastic Surgery, > > > > > Bioenergetics Group, Wallenberg Laboratory, Sahlgrenska > > > University > > > > > Hospital, Gštenborg University, Gštenborg S-143-45, Sweden > > > > > > > > > > Skeletal muscle viability is crucially dependent on the tissue > > > > > levels of its high energy phosphates. In this study we > > > investigated the > > > > > effect of the preservation medium Perfadex and illumination > > with > > > Singlet > > > > > Oxygen Energy (SOE). Singlet oxygen can be produced > > > photochemically > > > > > by energy transfer from an excited photosensitizer. The energy > > > emitted > > > > > from singlet oxygen upon relaxation to its triplet state is > > > captured > > > > > as photons at 634 nm and is here referred to as SOE. Rat hind > > > limb > > > > > rectus femoris muscles were preserved for five hours at 22 ¡C in > > > > Perfadex, > > > > > saline, SOE illuminated Perfadex or SOE illuminated saline. > > > Extracts > > > > > of the muscles were analysed by 31P NMR. Data were analysed > > > using two- > > > > > way analysis of variance and are given as mean values (μmol/g > > > dry > > > > > weight) ± SEM. The ATP concentration was higher (p = 0.006) in > > > > > saline groups (4.52) compared with Perfadex groups (2.82). > > There > > > > > was no statistically significant difference in PCr between the > > > saline > > > > > groups (1.25) and Perfadex groups (0.82). However, there were > > > > higher (p = > > > > > 0.003) ATP in the SOE illuminated groups (4.61) compared with > > > the > > > > > non-illuminated groups (2.73). The PCr was also higher (p < > > > 0.0001) > > > > > in the SOE illuminated groups (1.89) compared with the non- > > > illuminated > > > > > groups (0.18). In conclusion, Perfadex in this experimental > > > model > > > > > was incapable of preserving the high energy phosphates in > > > skeletal > > > > > muscle during 5 hours of ischemia. Illumination with SOE at 634 > > > nm > > > > improved > > > > > the preservation potential, in terms of a positive effect on > > the > > > energy > > > > > status of the muscle cell. > > > > > > > > > > > > > > > PMID: 12672510 [PubMed - indexed for MEDLINE] > > > > > Transplant Proc. 2005 Jan-Feb;37(1):518-20. > > > > > > > > > > Singlet oxygen energy illumination during moderate cold ischemia > > > > > prolongs the survival of concordant hamster xeno-heart > > > transplants. > > > > > > > > > > Lukes DJ, Skogsberg U, Nilsson A, Lundgren A, Olausson M, > > > > > Soussi B. > > > > > Department of Surgery and Transplantation, Wallenberg > > > Laboratory for > > > > > Cardiovascular Research, Gšteborg, Sweden. > > > > > > > > > > INTRODUCTION: Singlet oxygen energy (SOE) is a potent inhibitor > > > > > of reactive oxygen species (ROS) in vitro and in vivo in > > certain > > > dose > > > > > ranges and can improve the levels of high-energy phosphates > > > (HEP) in > > > > > concordant hamster xeno-heart transplants. Some data indicate > > > that a > > > > > certain degree of cold ischemia (CI) might be beneficial to > > > > > xenotransplants. We investigated if SOE illumination of hamster > > > > > xeno-hearts during moderate cold ischemia (CI) improved graft > > > > > survival. > > > > > MATERIALS AND METHODS: Eighteen hearts from Golden Syrian > > > hamsters > > > > > (70 to 80 g) were subjected to 8 hours of CI in cold (+4 > > degrees > > > C) > > > > > saline solution (NaCL, 0.9%) before heterotopic cervical > > > > transplantation to > > > > > rats (220 g). Among the treatment group (n = 8), SOE was > > > > > produced by illuminating the hearts for 10 minutes every 30 > > > minutes with > > > > > photons at lambda 634 nm with the Oxylight equipment. Graft > > > function was > > > > > evaluated every 6 hours after transplantation with digital exam > > > > > until cessation of heart beats. RESULTS: The graft survival of > > > > > SOE-illuminated ischemic hamster xenografts was 2.34 +/- 0.56 > > > versus > > > > > 1.15 +/- 0.37 days in the control group (P < .05). All hearts > > > > > displayed immediate graft function versus 70% in the controls > > > (NS). > > > > > CONCLUSIONS: > > > > > SOE illumination at lambda 634 nm during moderate cold > > ischemia > > > (+4 > > > > > degrees C) can improve the survival of concordant hamster xeno- > > > heart > > > > > transplants. The exact mechanism(s) are currently unknown, but > > > the > > > > > effect might in part be exerted by a combination of reduced > > > > > production of ROS and increased oxidative phosphorylation. > > > > > > > > > > Publication Types: * Research Support, Non-U.S. Gov't > > > > > PMID: 15808696 [PubMed - indexed for MEDLINE] > > > > > > > > > > > > > > > Non-published research (study in Spanish): > > > > > > > > > > Therapy Valkion, its effect on non-traumatic joint pain. > > > > > > > > > > Dra. Flora Mar'a Hern‡ndez Pedraza, Dr. Orlando S‡nchez > > > > > Freire . Orlando Freire. Especialista de 1er Grado en > > > > > Medicina F'sica y Rehabilitaci—n.Diplomado en Fitoterapia > > > > > Cl'nicaÉ.Clinic Natural and Traditional Medicine. Santa Clara. > > > > > Santa Clara. Villa Clara. Villa Clara. > > > > > > > > > > We studied a total of 300 patients with non-traumatic joint pain > > > > > from the clinic of traditional medicine and natural Santa Clara > > > in the > > > > > first period from February 2000 until February 1, 2001. 3 > > > groups were > > > > > formed with 100 patients each: a control group with acupuncture > > > and two > > > > > tanks, one with phototherapy and another with VALKION therapy. > > > The > > > > average > > > > > number of days of treatment was 16 days, ending two months of > > > > > treatment patients treated with VALKION had no relapses and > > > decreased > > > > > consumption of drugs and therefore believe that this therapy > > > should > > > > be used in > > > > > patients with this condition because it is odourless and > > > harmless to > > > > > the patient as well as by its high therapeutic effectiveness. > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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