Re: New to board and questions for Stan.

[Guest guest]

There are published references of brain inflatmation in austic patients related

to a herpes

virus. I think the first one is from 1986. I think more people will catch on

at some point.

- Stan

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Eur Child Adolesc Psychiatry. 2002 Jun;11(3):142-6. Related Articles, Links

Autistic symptoms following herpes encephalitis.

Ghaziuddin M, Al-Khouri I, Ghaziuddin N.

Division of Child and Adolescent Psychiatry, University of Michigan Medical

Center, Ann

Arbor 48109-0390, USA. mghaziud@...

Autism is a childhood onset neurodevelopmental disorder characterized by

reciprocal

social deficits, communication impairment, and rigid ritualistic interests, with

the onset

almost always before three years of age. Although the etiology of the disorder

is strongly

influenced by genes, environmental factors are also important. In this context,

several

reports have described its association with known medical conditions, including

infections

affecting the central nervous system. In this report, we describe an 11-year-old

Asian

youngster who developed the symptoms of autism following an episode of herpes

encephalitis. In contrast to previous similar reports, imaging studies suggested

a

predominant involvement of the frontal lobes. At follow-up after three years, he

continued

to show the core deficits of autism. This case further supports the role of

environmental

factors, such as infections, in the etiology of autism, and suggests that in a

minority of

cases, autistic symptoms can develop in later childhood.

Publication Types:

Case Reports

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Dev Med Child Neurol. 1991 Oct;33(10):920-4. Related Articles, Links

Autistic syndrome with onset at age 31 years: herpes encephalitis as a possible

model for

childhood autism.

Gillberg IC.

Department of Pediatrics and Child Psychiatry, University of Goteborg, Sweden.

The author describes a previously healthy man who contracted herpes encephalitis

at the

age of 31 years, and over the following months developed all the symptoms

considered

diagnostic of autism. This case report casts doubt on the notion of autism as an

exclusively developmental disorder. It is suggested that temporal lobe damage

may cause

autism in some cases.

Publication Types:

Case Reports

PMID: 1743418 [PubMed - indexed for MEDLINE]

--------

J Autism Dev Disord. 1986 Sep;16(3):369-75. Related Articles, Links

Onset at age 14 of a typical autistic syndrome. A case report of a girl with

herpes simplex

encephalitis.

Gillberg C.

Publication Types:

Case Reports

PMID: 3558293 [PubMed - indexed for MEDLINE]

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>

> My daughter is six and we have been on biomed for over a year now.

> We have done the MB12 shots for 5 months w/o any noticable gains.

> Now I want to give the nasal spray a try. My daughter is on the

> third week of Sporonox and I want to start Valtrex after we are done

> with that, which should be in a couple of weeks. I have such a tough

> nut that just does not respond. I hope we get some nice things from

> Valtrex and MB12 spray. Keeping my fingers crossed. My questions...

>

> Does Valtrex help with inflammation of the brain? My daughter has a

> huge head. MRI did not show anything. I believe she needs some anti-

> inflammatory.

>

> She is also on Pentasa for a month now. Will that cause any problems

> when given together with Valtrex?

>

> She has been on Transfer Factor for four months and I have not seen

> any changes from it. Should I stop TF before starting Valtrex?

>

> TIA for your help.

>

> Rima

>