Guest guest Posted January 8, 2008 Report Share Posted January 8, 2008 I'm just outside of Lexington, KY - about 1-1/2 hours away. Mindy , DVM, CCRT BARHC --- " Dr. Pam Nichols " wrote: > Any rehab folks in the Cincinnati area? > > > > > > _____ > > From: VetRehab > [mailto:VetRehab ] On Behalf > Of Freedman > Sent: Monday, January 07, 2008 7:18 PM > To: VetRehab > Subject: Re: Tendon issues with > Fluoroquinolones > > > > Toni > > I'm not sure where you got your info' but it isn't > correct-cruciate dz isn't > a result of inflamm-we don't see as many acute tears > in humans because of > dog's comformation and activity, as well as an > associated collagen > degenration and loads. The inflammation is not > pre-existing-it's been there > as part of the inflamm repsonse to the ligamentous > pathology, not the > opposite. Also, meniscal injury contributes to this > as well. > > > > Freedman VMD CCRT > > Re: Tendon issues with > Fluoroquinolones > > Mark, > > Quinolone induced tendon ruptures have been > described in the literature > dating back to the early and mid 80's. A medline > search will reveal many > cited references. These cases are rare, although I > have treated one patient > with an achilles tendon rupture and had a co-worker > rupture both achilles > tendons while on quinolones. I have not heard this > mentioned occuring in the > canine population, however, much of the phase I and > II studies were > performed on dogs. > > > > Ria Acciani MPT > > Acciani PT > > Advanced Canine Rehabilitation > > 6 Kenquit Road > > > > > > > > > Happy New Year! > I just have to stick my 2 cents in on this topic. I > don't think that we can > extrapolate from human medicine and condemn > fluoroquinolones in dogs. > Additionally, both of the drugs cited are not the > commonly used > fluoroquinolones in veterinary medicine. I think > that until there is hard > evidence that supports discontinuing using them in > dogs, we should not make > make suggestions to avoid their usage. Experience > wise, since Baytril hit > the market (15 - 20 years ago?) I have not seen any > tendon injury associated > with their usage, nor have I seen any tendon injury > after their usage. Does > === message truncated === ________________________________________________________________________________\ ____ Looking for last minute shopping deals? Find them fast with Yahoo! Search. http://tools.search.yahoo.com/newsearch/category.php?category=shopping Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2008 Report Share Posted January 9, 2008 I am in Dayton. Pavlakos, PT, CCRP Our hearts Canine Rehab -----Original Message-----From: VetRehab [mailto:VetRehab ]On Behalf Of Dr. Pam NicholsSent: Monday, January 07, 2008 9:21 PMTo: VetRehab Subject: Cin. OH rehab Any rehab folks in the Cincinnati area? From: VetRehab [mailto:VetRehab ] On Behalf Of FreedmanSent: Monday, January 07, 2008 7:18 PMTo: VetRehab Subject: Re: Tendon issues with Fluoroquinolones Toni I'm not sure where you got your info' but it isn't correct-cruciate dz isn't a result of inflamm-we don't see as many acute tears in humans because of dog's comformation and activity, as well as an associated collagen degenration and loads. The inflammation is not pre-existing-it's been there as part of the inflamm repsonse to the ligamentous pathology, not the opposite. Also, meniscal injury contributes to this as well. Freedman VMD CCRT RE: Tendon issues with Fluoroquinolones Hi All, If we come up with a survey, Clean run may be willing to put it up on their website. Clean run is “the” magazine company for agility people. This way we could reach a large percentage of canine athlete owners. I am not a researcher so I would need some help. What I was thinking was to ask people: Has your athlete torn his or her cruciate? Was your athlete on any medication just prior to or when this happened? If yes, was an antibiotic or NSAID? (this way people will not freak out thinking ab’s are going to cause cruciate damage?????) If your dog has torn their cruciate and was on or recently on an antibiotic, which antibiotic (list 10 or more) Maybe a similar question with NSAIDs Again, any thoughts/help or letting me know this would mot be a good thing to do would be appreciated J Laurie McCauley, DVM TOPS Veterinary Rehabilitation Grayslake, IL drmctops-vet-rehab www.tops-vet-rehab.com From: VetRehab [mailto:VetRehab ] On Behalf Of dogptSent: Saturday, January 05, 2008 8:14 PMTo: VetRehab Subject: Re: Tendon issues with Fluoroquinolones Mark, Quinolone induced tendon ruptures have been described in the literature dating back to the early and mid 80's. A medline search will reveal many cited references. These cases are rare, although I have treated one patient with an achilles tendon rupture and had a co-worker rupture both achilles tendons while on quinolones. I have not heard this mentioned occuring in the canine population, however, much of the phase I and II studies were performed on dogs. Ria Acciani MPT Acciani PT Advanced Canine Rehabilitation 6 Kenquit Road Happy New Year!I just have to stick my 2 cents in on this topic. I don't think that we can extrapolate from human medicine and condemn fluoroquinolones in dogs. Additionally, both of the drugs cited are not the commonly used fluoroquinolones in veterinary medicine. I think that until there is hard evidence that supports discontinuing using them in dogs, we should not make make suggestions to avoid their usage. Experience wise, since Baytril hit the market (15 - 20 years ago?) I have not seen any tendon injury associated with their usage, nor have I seen any tendon injury after their usage. Does anyone on this list know of any citation or reference addressing this human problem? By the way, I do not work for Bayer nor am I getting paid to say this (I wish I was though). Mark B. Parchman, DVM, DACVS, CVA <clip_image002.gif> 1245 SE 3rd St., Suite C3 Tel Bend, Oregon 97702 Fax tomlinson wrote: Hi Laurie It is something we always talked about when I used to treat horses, not sure in the small animal world but I avoid them in canine athletes Tomlinson BVSc MS PhD DACVS CCRP Certified Canine Rehabilitation Practitioner Twin Cities Animal Rehabilitation Clinic 12010 Riverwood Dr, Burnsville MN 55337 www.tcrehab.com <mime-attachment.jpeg> From: VetRehab [mailto:VetRehab ] On Behalf Of Dr. Laurie McCauleySent: Friday, January 04, 2008 3:15 PMTo: VetRehab Subject: Tendon issues with Ab'sl? I saw this come across another list that I belong to and was wondering if anyone had heard anything about it? Group Sues FDA for Stronger Warnings Jan 3, 7:16 PM (ET) WASHINGTON (AP) - A consumer group sued the Food and Drug Administration Thursday, charging the agency is ignoring calls for stronger warnings that Cipro and similar antibiotics may cause serious tendon injuries. Labels of the fluoroquinolone family of antibiotics - drugs that include the popular Cipro and Levaquin - already warn about rupture of tendons and other tendon injuries, but at the bottom of a list of other side effects. The consumer group Public Citizen wants those warnings upgraded to the FDA's most severe type, a so-called black-box warning - and for patients to get pamphlets with every bottle that describe the risk. It argues that too few patients know they're supposed to quit using the drugs if they experience symptoms such as pain or inflammation, before the tendon actually ruptures. Public Citizen filed a petition seeking the stronger warning in August 2006. The state of Illinois had filed a similar petition the previous year. The FDA is violating its own statutes and putting patients at risk in taking so long to settle the issue, Public Citizen said in the suit filed in U.S. District Court for the District of Columbia. When Public Citizen first filed the petition, FDA's database showed 262 reports of tendon ruptures between November 1997 and December 2005, along with hundreds of other tendon problems in users of these antibiotics. Since then, the FDA has received an additional 74 reports of tendon ruptures, said Public Citizen's Dr. Sidney Wolfe. Only a fraction of drug side effects typically are reported to the agency, he noted. An FDA spokesman said the agency was evaluating the lawsuit and declined comment. Warren, NJ 07059 I am using the free version of SPAMfighter for private users.It has removed 3794 spam emails to date.Paying users do not have this message in their emails.Try SPAMfighter for free now! Quote Link to comment Share on other sites More sharing options...
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