Re: Symptoms and Thanks [1 Attachment]

[Guest guest]

Dr. Grim, what causes the high renin? 74.16 (0.25-5.82)

- 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank

pain. Treating with DASH. 2-Day ave w/o meds = BP 133/77 HR 61 BS 132. D/C

Spironolactone 12/20/2011 due to adverse SX.

Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, Gynecomastia, MDD

and PTSD.

Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg aspirin and

Metformin 2000MG. Started washing Spironolactone 12/20/11 to prepare for AVS.

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> >> > > > > > > > > > >> Did I answer your question, ?

> >> > > > > > > > > > >> In the time when I had this visit to my PCP I already

subscribed

> >> > > > > > > > > > >> to this group and learned about spiro and eplerenone,

but I didn't

> >> > > > > > > > > > >> communicate either with group or with Dr. Grim yet. I

started

> >> > > > > > > > > > >> eplerenone without any proof and hope, just out of

desperation,

> >> > > > > > > > > > >> since my BP and my condition were killing me and EVERY

BB, Calcium

> >> > > > > > > > > > >> channel, and other made me feel terrible. No mention

that clonidine

> >> > > > > > > > > > >> almost killed me.

> >> > > > > > > > > > >> After the first day on eplerenone, my BP was 130/80 -

I do not

> >> > > > > > > > > > >> remember that I ever had this BP in my life.

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> >> > > > > > > > > > >> Natalia

> >> > > > > > > > > > >> From: Bingham <jlkbbk2003@>

> >> > > > > > > > > > >> To: " hyperaldosteronism "

<hyperaldosteronism

> >> > > > > > > > > > >>

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[Guest guest]

Natalia, I would be barely able to drag my body around with a TSH of 2.51 mIU/L.  A good level for TSH is about 1.00, but you need FreeT3 and Free T4 to get the whole picture.  If your pituitary is not up to snuff, a TSH is no good because it measures a pituitary hormone (TSH) and not actual thyroid hormones. Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of Natalia Kamneva [Attachment(s) from Natalia Kamneva included below] Dr. Grim, you looked at this file back in October, when I have sent it to you directly.

[Guest guest]

What caused the big drop do u think. CT?Recommend you give him a copy of the Hypertension Primer to get him up to speed. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertension

Thanks Dr. Grim for this info. When I noticed my GFR was improving and discussed it with my doc he rejected the possibility although I was showing him my GFR chart (attached). Max.62M L adenoma by NP59 scan. Aldos=1065…2056 [28-860] pmol/L, Renin=6 [<30] ng/L. med combo #76={Spiro=100, Amlo=2x5mg, Indap=2.5mg, Ramip=2x2.5mg, Metf=2x500mg, Crestor=20mg, Feno=67mg, K.Cl=6x20mEq, Motilium 3x10mg}{K=4.4}{not DASHing but low-salt diet just slightly above craving while keeping K/Na ratio constant, heat intolerance, insulin resistance} A fall in eGFR with epeler or any other drug that lowers BP may well be the result of lowering the perfusion pressure to a damaged glomerlus (kidney). If the damage was due to the HTN or high salt/aldo then we expect it to improve over time. This has been documented over 40 years ago with older BP meds. So the issue is does the Dr. have enough experience to wait this out and see if renal function improves. If not, and low diet Na is documented by urine testing if pt has PA, then may want to choose another BP med. And watch eGFR as well with it. CE Grim.