(mentions CMT) Children: Musculoskeletal complications of neuromuscular disease

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Phys Med Rehabil Clin N Am. 2008 Feb;19(1):163-94.

Musculoskeletal complications of neuromuscular disease in children.

Driscoll SW, Skinner J.

Pediatric Physical Medicine and Rehabilitation, Mayo Clinic, 200

First Street SW, Rochester, MN 55901, USA; Mayo Clinic College of

Medicine, 200 First Street SW, Rochester, MN, 55901 USA.

A wide variety of neuromuscular diseases affect children, including

central nervous system disorders such as cerebral palsy and spinal

cord injury; motor neuron disorders such as spinal muscular atrophy;

peripheral nerve disorders such as Charcot-Marie-Tooth disease;

neuromuscular junction disorders such as congenital myasthenia

gravis; and muscle fiber disorders such as Duchenne's muscular

dystrophy. Although the origins and clinical syndromes vary

significantly, outcomes related to musculoskeletal complications are

often shared. The most frequently encountered musculoskeletal

complications of neuromuscular disorders in children are scoliosis,

bony rotational deformities, and hip dysplasia. Management is often

challenging to those who work with children who have neuromuscular

disorders.