Charcot-marie-tooth disease and the cavovarus foot

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Foot Ankle Clin. 2008 Jun;13(2):259-74.

Charcot-marie-tooth disease and the cavovarus foot.

Beals TC, Nickisch F.

University of Utah School of Medicine, University Orthopaedic Center,

590 Wakara Way, Salt Lake City, UT 84108, USA.

This article focuses on the cavovarus foot shape, with particular

emphasis on those patients who have Charcot-Marie-Tooth disease. Recent

greater understanding of this deformity has led to a better

appreciation of how the underlying condition drives deformity

progression and treatment of the problems associated with it. The basic

science underpinning the development of Charcot-Marie-Tooth disease is

reviewed and some elements of the importance of the genetic variability

are emphasized. The mechanics of the development of the cavovarus foot

deformity in patients who have this neuromuscular condition are

reviewed and the evaluation of such patients is described. The surgical

options for treatment are reviewed and the outcomes of studies relevant

to surgical planning for this patient population are summarized.