Guest guest Posted April 27, 2008 Report Share Posted April 27, 2008 Thanks so much for introducing yourself, Bruce, and welcome to the group. CMT affects each of us differently, but symptoms seem to gradually come on; some earlier, some later. There are two MPZ gene mutations (myelin protein zero) in CMT Type 1B, one of which causes a late-onset neuropathy with prominent axonal loss. The oldest person I know of was 70 when she was finally diagnosed with CMT Type 1A (through the DNA blood test), after mis-diagnoses of Polio, MS, Muscular Dystrophy, Frederick's Ataxia, Lupus, Rheumatoid Arthritis, and Fibromylagia. A good neurologist should take a complete family history of Joe first, do a manual exam, the EMG/NCV tests and the DNA test to confirm CMT. Again, welcome and I hope we can be of some help to you and Joe. Perhaps others here with late onset will step in to help. Gretchen Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.