Guest guest Posted August 5, 2008 Report Share Posted August 5, 2008 Translated from Spanish by Babel Fish The genetic selection allows that the first baby without a hereditary ailment is born in Spain http://www.elpais.com/articulo/sociedad/nina/tendra/huesos/cristal/elp epusoc/20080805elpepusoc_3/Tes This girl will not have ' bones of cristal' The genetic selection allows that the first baby without a hereditary ailment is born in Spain that causes to fractures all the life Madrid - 05/08/2008 It had 50% of probabilities of being born with the crystal bones, but a technical outpost of selection has avoided genetic it. For the first time, a Spanish baby has been able to escape of this serious well-known hereditary disease to cause to manifolds bony fractures during all the life. The girl, born yesterday in Alicante, has come to the free world of the imperfect osteogénesis. She will be able to make a life normal. " Before only we could know if the baby had the disease as of the fourth month of gestation. If the mutation existed, the then mother decided if she aborted or no. Era very duro " , she indicates to ELPAÍS.com the director of the genetic training center Genomic Systems, , who has worked in the case next to the center of attended reproduction CREATES of Valencia. ' children probeta' they are already three million A group of affected Cordovan by the disease of ' bones of cristal' it creates an association Identified a new gene that causes ' bones of cristal' The news in Spanish is other languages The Genetic Diagnosis Preimplantacional (DGP), also known like genetic selection embryos, implies the combined use of techniques of attended reproduction and molecular genetics. In the case of the girl of Alicante, the director, the parents explains, who are natural of Elche, were put under a treatment of test-tube fertilization, from the technique of espermática microinjection. Some cells of the produced embryos happened through examinations and it was discovered that two of the five embryos were totally healthy. In December of the past year SHE CREATES, in charge of the attended reproduction, transferred the free embryos of the disease to the uterus. It was the second attempt of the pair, that from the 2006 a son looked for. In first, in March of 2007, eight embryos were obtained, of which two four were healthy, but the pregnancy did not leave ahead. According to , in the people with this disease the lack of an enzyme causes that the bones are broken with any blow or fall. In this case, the mother of the girl and several members of the family are affected by this genetic pathology. The girl of Alicante breaks therefore the process of transmission of this ailment. " The best thing is than this girl is totally healthy. That is, their children do not have risk of having the disease. Cadena " is had broken; , it emphasizes the director of Genomic Systems. The person in charge of the Unit of Reproductive Genetics of Genomic Systems, Xavier Vendrell, is outstanding that the application of the technique of DGP in this new case " it is an example of how they are extended day to day the number of diseases that can be detected in embriones " . On the other hand, doctor Carmen Calatayud, director of CREATE, have affirmed that " correcto " bases of the success consists of realising a diagnosis;. The alterations that the imperfect osteogénesis brings about include/understand from the predisposition to the fractures to the low stature, very severe skeletal deformations and the perinatal death (in dates next to the childbirth) in their more aggressive forms. Also it can even inflict casualties to disturbances in the teething and of hearing. The use of techniques similar to the employee in the case of the baby who could already suffer the disease of the crystal bones has allowed to obtain the birth of healthy children of afflicted parents of quística fibrosis, muscular dystrophy of Duchenne, hipocaliémica periodic paralysis and other chromosomic diseases. At the moment they are working in many other diseases like the syndrome of Pfeifer, the disease of Charcot-Marie-Tooth, the miotónica dystrophy of Steinert or the syndrome of Marfan. Quote Link to comment Share on other sites More sharing options...
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