Jump to content
RemedySpot.com

Signaling in muscle atrophy and hypertrophy.

Rate this topic


Guest guest

Recommended Posts

Guest guest

Physiology (Bethesda). 2008 Jun;23:160-70.

Signaling in muscle atrophy and hypertrophy.

Sandri M.

Department of Biomedical Sciences, University of Padova; Dulbecco

Telethon Institute; and Venetian Institute of Molecular Medicine,

Padova, Italy

Muscle performance is influenced by turnover of contractile proteins.

Production of new myofibrils and degradation of existing proteins is

a delicate balance, which, depending on the condition, can promote

muscle growth or loss. Protein synthesis and protein degradation are

coordinately regulated by pathways that are influenced by mechanical

stress, physical activity, availability of nutrients, and growth

factors. Understanding the signaling that regulates muscle mass may

provide potential therapeutic targets for the prevention and

treatment of muscle wasting in metabolic and neuromuscular diseases.

Link to comment
Share on other sites

Join the conversation

You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...