Re: Exercise 'reverses' muscle ageing

[Guest guest]

Okay, I still do not understand why exercise is contraindicated for CMT folks.

Is there something produced in our bodies when we exercise, which is then toxic

to our nerves?

What's up?

>

> Exercise 'reverses' muscle ageing

>

> http://news.bbc.co.uk/2/hi/health/6680621.stm

>

> A twice-weekly trip to the gym may not just give you stronger

> muscles - it may give you younger muscles as well. Research on over-

> 65s has shown that regular resistance training appears to reverse

> signs of ageing in the muscles.

>

> Analysis of muscle tissue showed the molecular machinery powering

> muscle cells became as active as that in 20-year olds after exercise.

>

> Its authors say the Canadian study, published in the journal PLoS

> One, shows the benefits of remaining active.

>

> Around 25 healthy adults over the age of 65 were given twice-weekly

> hour-long training sessions for six months. The results were compared

> with participants aged 20-35 years.

>

> Before the sessions, which used standard gym equipment and a

> programme of 30 contractions of each muscle group, the older adults

> were 59% weaker than the younger adults.

>

> This shows that it's never too late to start exercising and that you

> don't have to spend your life pumping iron in a gym to reap benefits

>

> But after the training the older adults were only 38% weaker.

>

> The researchers also took tissue samples to look at changes in the

> mitochondria, the rod-like " power plants " that sit within every cell

> and generate energy.

>

> Previous studies have suggested that mitochondrial dysfunction is

> involved in the loss of muscle mass and function commonly seen in

> older people but the team wanted to look specifically at the gene

> activity in the mitochondria.

>

> The results showed the gene expression - the generation of functional

> proteins by a gene - declined with age.

>

> But exercise resulted in a reversal of the gene expression back to

> levels similar to those seen in the younger adults.

>

> Dr Simon Melov, who co-led the research at McMaster University

> Medical Centre in Hamilton, Ontario, said: " We were very surprised by

> the results of the study.

>

> " We expected to see gene expressions that stayed fairly steady in the

> older adults.

>

> " The fact that their 'genetic fingerprints' so dramatically reversed

> course gives credence to the value of exercise, not only as a means

> of improving health, but of reversing the ageing process itself,

> which is an additional incentive to exercise as you get older. "

>

> Co-author Dr Mark Tarnopolsky added that a further four months of

> follow-up found most of the older adults were no longer doing formal

> exercise in a gym, but were doing resistance exercises at home,

> lifting soup cans or using elastic bands.

>

> " They were still as strong, they still had the same muscle mass. "

>

> " This shows that it's never too late to start exercising and that you

> don't have to spend your life pumping iron in a gym to reap

> benefits. "

>

> Professor n McMurdo, head of ageing and health at the University

> of Dundee, said: " There is an age-related loss of muscle from about

> 35 onwards.

>

> " It used to be thought this was completely irreversible but what we

> have begun to understand is that there's a sedentary loss as well. "

>

> " We know that people in their 90s can regain lost muscle tissue and

> lost muscle strength with quite a modest amount of exercise. "

>

> " The encouraging thing is it doesn't have to be vigorous and only a

> little exercise is necessary. "

>