Guest guest Posted August 20, 2008 Report Share Posted August 20, 2008 In 2008 researchers at the Salk Institute discovered that AICAR given to experimental mice significantly improves their performance in endurance-type exercise, apparently by converting fast-twitch muscle fibers to the more energy-efficient, fat-burning, slow-twitch type.[2] It stimulates glucose uptake and increases the activity of p38 mitogen- activated protein kinases á and â in skeletal muscle tissue,[3] as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell.[4] http://en.wikipedia.org/wiki/AICAR more links there. Quote Link to comment Share on other sites More sharing options...
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