(CMT / HMSN 1) Different types of fatigue in patients with facioscapulohumeral

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Neurol Sci. 2008 Sep;29 Suppl 2:S238-40.

Different types of fatigue in patients with facioscapulohumeral

dystrophy, myotonic dystrophy and HMSN-I. Experienced fatigue and

physiological fatigue.

Kalkman JS, Zwarts MJ, Schillings ML, van Engelen BG, Bleijenberg G.

Department of Medical Psychology, Radboud University Nijmegen Medical

Centre, Nijmegen, The Netherlands.

Although fatigue is a common symptom in neuromuscular disorders,

little is known about different types of fatigue.

Sixty-five FSHD, 79 adult-onset MD and 73 HMSN type I patients were

studied.

Experienced fatigue was assessed with the CIS-fatigue subscale.

Physiological fatigue was measured during a 2-min sustained maximal

voluntary contraction of the biceps brachii muscle using the twitch

interpolation technique to assess central activation failure (CAF)

and peripheral fatigue.

Experienced fatigue, CAF and peripheral fatigue appeared to be

predominantly separate types of fatigue.