Negative (?) Effects of Calorie Restriction

[Guest guest]

The following citations are made in Alcedo et al., " Regulation of C. Elegans

Longevity by Specific Gustatory and Olfactory Neurons, " _Neuron_ Vol 41, Jan

2004:

_____

Calorically restricted animals develop more slowly than normal, are thin, and

have reduced fecundity (Klass, 1977).

______

Caloric restriction extends life span and also delays reproduction (Klass,

1977; Koubova and Guarente, 2003).

______

It's worth noting that when rats with reduced reproductive activity are fed

higher-calorie diets, the ability to reproduce resumes in tact, even at ages

where control rats were no longer able to reproduce or were dead. So the effect

of calorie restriction is to delay growth, reproduction, and death, delaying

the former two until a time when resources are more abundant, rather than

permanently harming that capacity.

Chris