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Reflux question. For the past month or so, has been all of a sudden

having frequent reflux. I remember exactly, it was four days after her MMR

vaccine that she started doing these small vomits every day for several days.

I was watching her for EVERYTHING at that time, that's how I remember this,

though obviously it has nothing to do with the vaccine itself.

Every single day, at least a couple times a day (ever since then), she'll

have these " urps " I call them, like a burp but something comes up and she

swallows it (SORRY!). Then sometimes you'll just see her do a sort of big

burp but with no noise, just the physical look of that, then sometimes she'll

have a spit-up (not a full blown big vomit) where stuff actually comes out.

It's like vomit but there's only a little.

I spoke with her ped who suggested we might end up trying Zantac for a while

and see if it helps. He said the only other thing to do would be a Ph probe,

which I obviously don't want!

I say obviously because this reflux doesn't seem to be causing any trouble.

She's infection-free at the moment, nothing seems to be resulting from this,

so do I need to really do anything about it?

Any advice on how to proceed... do I document the episodes? I don't relish

the idea of her taking a med when she seems to not be bothered by this. Other

than discomfort, why would you take the med if there seems to be no other

trouble from it?

Thanks for any info...

(mom to , age 2-1/2, polysaccharide antibody def, IgA def)

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,

I suspect a food allergy. Has she tried a new food lately that could be

causing her some problems? How about new medicines? I don't think that

would just " develop " reflux suddenly. I especially don't think it's

linked to the MMR, although I could be wrong. Seems just too coincidental

to me.

Ray, mother to Tabitha (age 6), Autumn, age 3 (IgG Def., asthma,

chronic sinusitis, and allergies), and Duncan Avery, 6 months

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  • 6 years later...

Hi Natasa,

I think the post was number 38746 posted January 23rd.Was it the post

regrding melatonin helping reflux disease ?

Sharon

>

>

> I posted a paper similar to one below a while ago, would like to

trace it

> again :) it was on reflux in kids sucessfully treated with

antioxidants...

> Does anyone remember more or have it saved?

>

> nx

>

>

>

> Eur J Pharmacol. 2008 Jul 28;589(1-3):233-8. Epub 2008 May 7.

>

> Effect of quercetin, flavonoids and alpha-tocopherol, an

antioxidant

> vitamin, on experimental reflux oesophagitis in rats.

>

> Rao CV, Vijayakumar M.

>

> Gastropharmacology laboratory, Pharmacognosy and

Ethnopharmacology

> Division, National Botanical Research Institute, Rana Partap Marg,

Lucknow,

> Uttar Pradesh, India. ethnopharmacology1@...

>

>

> Protective effect of quercetin and alpha-tocopherol on

experimental

> reflux oesophagitis in rats was investigated. Rats received

quercetin, (100

> mg/kg), alpha-tocopherol (16 mg/kg), omeprazole (30 mg/kg) given at

1 h

> prior to surgery. Quercetin and alpha-tocopherol significantly

inhibited the

> oesophagitis index to 1.33+/-0.12 (P<0.001) and 1.83+/-0.14

(P<0.001)

> respectively, as compare to control group 3.5+/-0.21. Further, acid

and

> pepsin out put of gastric contents were significantly decreased in

treated

> groups. Indeed, quercetin significantly inhibited the lipid

peroxidation

> (from 0.69+/-0.05 to 0.43+/-0.04 nmol of malonyldialdehyde (MDA)/mg

protein)

> (P<0.001) and increased in levels of catalase to 29.5+/-2.7 units of

> catalase activity/mg protein and superoxide dismutase (SOD) to

92.4+/-10.5

> units/mg protein (P<0.001). The alpha-tocopherol and omperazole

showed

> significant inhibition in lipid peroxidation (0.34+/-0.02 and

0.38+/-0.01)

> (P<0.01) and enhanced the activities of catalase (34.3+/-3.6 and

31.5+/-3.4)

> (P<0.01) and SOD (87.3+/-9.2 and 76.60+/-6.9) activity. Quercetin

and

> alpha-tocopherol treated group significantly increased the

glutathione level

> to 36.5+/-2.78 (P<0.01) and 32.1+/-2.34 (P<0.05) respectively.

However, it

> altered the elevated levels of sialic acid and hexose contents in

> oesophageal tissue. Indeed, quercetin significantly decreased the

elevated

> plasma histamine content (P<0.05). Quercetin and alpha-tocopherol

> significantly attenuated the elevated level of collagen in

oesophageal

> tissue as of the omeprazole. The results suggest that antioxidants

could

> attenuate the severity of reflux oesophagitis and prevent the

oesophageal

> mucosal damage and validate its therapeutic use in gastroesophageal

reflux

> disease. PMID: 18547560

>

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