Usman's gut biofilm protocol

[Guest guest]

True Health Gut Biofilm Protocol™

Step One: Lysis and Detachment of the Polysaccharide Matrix

(empty stomach, 30-60 min prior to Step 2)

-Use of specific enzymes. (these are being refined and developed, as

the

enzymes we have available at this moment are not ideal)

-Use of a chelator that can grab hold of minerals in the Matrix. (if

not

implemented appropriately this may cause mineral depletion in the

body - do not

attempt chelation without proper medical supervision)

Step Two: Target the Microbe

- Consider using antibiotics, herbals, or homeopathics. (our office

has had

extensive experience with all three modalities, and have found that

the choice

" depends upon the kid " . We are also researching a fourth modality

that looks

quite promising for eradicating these pesty organisms.

Step Three: Clean Up

(This is the most crucial of all the steps. DO NOT SKIP!!! Give 1-2

hrs

after Step 2 if possible or at night)

-Here we use anything that can bind up the matrix (mucus), by

products of die

off, and potential metals in the gut.

Products include activated charcoal, alginate, clays, algaes,

zeolites,.... we

like pectin the best. Sometimes we use all of the above.

Other important factors

-Probiotics, of course.

-Anti-inflammatory agents such as EFA's, antioxidants, curcumin...

-Natural fermented foods such as kefir, kombucha...

-Healthful, non toxic foods (hormone- free, antibiotic-free, organic)

..

This protocol is still being developed and is not fully defined.

Theye have only been using this tretament for a couple of years This

takes time and the process is slow. It took years for some ou, it may

take time to reverse.

This is the repert she did at the DAn conferance

Dr Usman presented her Biofilm theory at the last DAN conference.

Basically she believes that there are viruses and bacteria which are

encased in the gut of our kids that regular anti fungals and meds

cannot get to becasue of the biofilm that surrounds them, so you have

to use EDTA to break down the biofilm which protects them and then

kill them off with anti fungals or antibiotics.

True Health Medical Center:

" Potential Implication of Biofilm Formation in Patients with ASD " ,

Presented to the Defeat Autism Now Think Tank, Oct. 11, 2007 Dr Usman

I presented a theory about the implications of biofilm production by

resistant strains of bacteria/fungus in our ASD patients who have

persistent dysbiosis. The literature search that I conducted with the

help of Conrick , MS and Sonja Hintz , RN was quite

convincing. The abnormal production of biofilm by resistant strains of

microorganisms may be a possible etiology of why many of our patients

who do not have positive stool cultures for yeast or pathogenic

bacteria do well when placed on antifungals and antibiotics, yet

relapse when they stop. The biofilm produced by these resistant

organisms can only be seen by electron microscopy and makes it

difficult to culture these bugs. This theory might also explain

subtypes of our ASD subpopulation who have abnormal behaviors, such as

head banging or agitation, that seem to be gut pain related, yet again

have negative studies. The third subset that this seems relevant for

is the group of children that have recurrent strep infections, OCD,

perseverative, or repetitive behaviors who get worse in the spring and

fall, yet may not test positive for strep.

Why do so many of our ASD kids have persistent dysbiosis? This is my

theory. We all know that the quality of our air, water and food is not

ideal and contains numerous toxins and pollutants. Our children have a

genetic susceptibility in their ability to handle this toxic burden.

Research shows us that resistant organisms tend to grow in toxic,

hostile environments, and after numerous rounds of antibiotics. They

maintain their viability by producing a polysaccharide matrix that

protects them from the hostile environment in which they are trying to

survive. This extracellular matrix is called biofilm. Our normal

flora also produce a natural biofilm, but resistant organisms produce

their own biofilm which then takes over, preventing the normal flora

from flourishing. Experiments done in vitro show that this

polysaccharide matrix is negatively charged, and that it is held

together by positively charged ions such as Ca, Mg, and Fe. Iron

seems to play a big role in how these bacteria evade the immune

system. Further work on VRSA/MRSA and pseudomonas biofilms in vitro

indicate that this biofilm may be penetrated by using a combination of

EDTA and an antibiotic; the studies used Vancomycin for Staph and

Gentamicin for Pseudomonas.

The protocol that my staff and I developed was presented in its

infancy at the October 2007 Think Tank. The Defeat Autism Now Think

Tank is usually a forum where ideas are presented for discussion and

further research. This protocol was not discussed in great detail (15

minutes was allotted for this discussion), and it was not meant for

wide distribution at this time. However, Dr. Bradstreet presented it

in his talk on New Advancements and clinicians and patients from all

over the world are now asking for our protocol.

However, let me start with a few caveats. First of all, this is brand

new. We have used this approach on about 60 patients. The first two

were 's and Sonja 's children - one with ASD/self injurious

behavior and one with colitis, no ASD. Both initial patients are

doing well. However, this treatment has to be individualized for each

patient's unique constitution and ability to handle both die-off and

detox type reactions. From our other patients we are seeing a variety

of responses from decreased hyperactivity and stimming, to increased

agitation, to no response. Of course we may have a few bumps along our

journey to recovery. The big bumps with this approach are related to

awakening the immune system to these organisms which it has not been

recognizing. The body finally sees the bacteria or the candida that

has been there creating other types of havoc all along. Acutely,

patients may experience vomiting, diarrhea, high temps. Rashes may

appear, especially if the die off is sudden. The other theoretical

issue is that the biofilm may be holding on to toxic metals such as

aluminum and lead. As this toxic biofilm degrades heavy metals may be

released into the gastrointestinal tract for excretion. Our protocol

was developed to address this possibility.

I urge all of you to have patience and wait for us to gather more data

on this approach so that you are presented with the safest, most

effective protocol. Remember, your doctor should implement this

approach gradually with the unique needs of your child in mind.

Because of the possibility for negative side effects, and the need to

closely monitor the patients, and the possible use of pharmaceuticals,

this treatment plan should be implemented only with the help of your

physician.