Guest guest Posted July 16, 2004 Report Share Posted July 16, 2004 This is interesting ... it seems folks with celiac (and by extension folk with IgA gluten intolerance) do NOT have a higher rate of IgE allergies. But they have a higher rate of atopic dermatitis. http://www.medscape.com/viewarticle/482687?src=mp Atopic Dermatitis Is Common in Patients With Celiac Disease NEW YORK (Reuters Health) Jul 06 - Although allergy prevalence does not significantly differ between patients with celiac disease and their relatives and spouses, atopic dermatitis is more common in these patients, according to a new study published in the June issue of the Journal of Allergy and Clinical Immunology. " Celiac disease is considered to arise from an inappropriate T-cell-mediated immune response against ingested gluten in genetically predisposed people, whereas the TH2-type lymphocytes are mostly involved in IgE-mediated reactions, " Dr. Carolina Ciacci and colleagues from the University of Naples, Italy, write. " The matter of possible coexistence of TH1- and TH2-type diseases is still debated. " The researchers examined allergy prevalence in 1044 adults with untreated celiac disease, their 2752 relatives, and 318 spouses at the moment of diagnosis. In addition, they assessed whether 1-year gluten-free diet had any effect on allergy prevalence. The subjects completed a standardized questionnaire at the moment of diagnosis for information on the presence and type of allergy symptoms. Subjects who reported any allergy underwent tests for allergy using a standard makeup of 20 antigens testing serum specific IgE. Selected individuals underwent PRICK tests. Patients with celiac disease were given the same allergy questionnaire at 1-year follow-up visit. At least one allergy was observed in 173 (16.6%) celiac disease patients, 523 (19%) relatives, and 43 (13.5%) spouses. Patients with celiac disease were more likely to have atopic dermatitis (3.8%) than were their relatives (2.3%) or spouses (1.3%). The presence of overt malnutrition or duration of undiagnosed disease did not affect the presence of allergy in general and atopic dermatitis. " No significant differences were found between first and follow-up visits for prevalence of allergic symptoms, " Dr. Ciacci and colleagues write. Still, " it cannot be excluded that a longer period of gluten-free diet may have an effect on allergy in patients with celiac disease, " they conclude. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2004 Report Share Posted July 19, 2004 <<This is interesting ... it seems folks with celiac (and by extension folk with IgA gluten intolerance) do NOT have a higher rate of IgE allergies. But they have a higher rate of atopic dermatitis.>> This IS interesting !! If anyone remembers i asked about ringworm ( a few months ago now) and was in quite a tizzy about it. It turned out that one cat carried RW but did not break with it and the other cat did get lesions. I started breaking out all over with what my DR. thought was RW. Finally got into the dermatologist and i have nummular dermatitis, which btw, isn't much fun. I have been working on the gluten factor and i really believe that i have a problem with it. I was in a hurry one day and got a burger from fast food and within about 15 minutes my heart rate went up quite a bit and i could feel my muscles getting tense. Kathy A. Quote Link to comment Share on other sites More sharing options...
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