Fw: omega3/info for Bipolar and Depression

[Guest guest]

interesting info on large omega 3 doses from another list

[smartdrugs] omega3/info for Bipolar and Depression

> At a seminar at the May 2004 American Psychiatric Association’s annual

> meeting, Jerry Cott PhD, an FDA researcher, had this to say about omega-

> 3, which is being investigated for treating bipolar and depression:

>

> Omega-3, he said, is a fatty acid that appears to work much like a calcium

> channel blocker. Not uncoincidentally, he related, ph Hibbeln MD

> of the NIH, who has led the way in omega-3 research, had been working

> on a calcium channel blocker study. Omega-3 competes with its sister

> fatty acid, omega-6, for the same enzyme chain. From there, omega-3 and

> omega-6 are metabolized, then stored as highly unsaturated fatty acid

> in tissue phospholipids.. The ideal ratio of omega-6 to omega-3 is one

> to one, but with modern diets favoring omega-6 at 20 to one it’s fairly

> obvious which fatty acid is going to win the battle of the enzyme chain.

>

> Less may also be more. Large doses may result in oxidative stress as

> omega-3 is being metabolized.. This may explain why some studies using

> EPA (an active ingredient of omega-3) failed at higher doses. Accordingly,

> Dr Cott recommends omega-3 be taken with vitamins C and E.

> =====

>

> " Knowing

> what is denied by the fearful:

> a matter of Choice that is NOT. "

> --t->

> ====

> dJinni

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