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smoking and alzheimers

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From: http://www.straightdope.com/classics/a5_096.html

Still, facts are facts. I quote: " A statistically significant inverse

association between smoking and Alzheimer's disease was observed at all levels

of

analysis, with a trend towards decreasing risk with increasing consumption "

(International Journal of Epidemiology, 1991). " The risk of Alzheimer's disease

decreased with increasing daily number of cigarettes smoked before onset of

disease. . . . In six families in which the disease was apparently inherited . .

..

the mean age of onset was 4.17 years later in smoking patients than in

non-smoking patients from the same family " (British Medical Journal, June 22,

1991).

" Although more data are needed . . . [an analysis of 19 studies suggests]

nicotine protects against AD " (Neuroepidemiology, 1994). Nicotine injections

significantly improved certain types of mental functioning in Alzheimer's

patients

(Psychopharmacology, 1992). One theory: nicotine improves the responsiveness

of Alzheimer's patients to acetylcholine, an important brain chemical.

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