Smoking: inverse association between cancer and inhalation

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From www.lcolby.com:

Some would argue, of course, that cigar and pipe smokers inhale less than

cigarette smokers (although, in my case, I inhale both pipes and cigars). If,

however, inhalation is a factor in the development of disease, it should show up

in relative inhalation rates for cigarette smokers. A study was, in fact,

conducted by Hill and Doll, which sought to classify cigarette smokers as

inhaling

vs. non-inhaling. At page 188 of the Report, there is a reference to a

" negative association " between inhaling and lung cancer, based on the " early "

Hill

and Dole studies.

In 1959, in fact, R.A. Fischer analyzed some of the Hill and Doll data and

concluded that inhalers have a lower rate of lung cancer than non-inhalers 21 .

Fischer's findings were incorporated into Table 8 of the 1982 Surgeon

General's Report, but the Report did not deal with this apparent paradox.