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tobacco and oxygenation

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I've always heard that smoking tobacco decreases tissue oxygenation and

assumed it was true.

But nicotine is widely regulized to stimulate metabolism significantly, when

consumed by smoking tobacco. This seems a contradiction. Since oxidation is

the ultimate requirement of any metabolism, how could smoking tobacco

simultaneously decrease tissue oxygenation and increase metabolism?

If anyone can help point out where I might be going wrong, I'd appreciate it.

Thanks,

Chris

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