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In most studies I have read the trigger for EN is not found in up to 50% of cases. This is true for all except this case from Russia. Why is it that triggers are figured out in Russia at a higher rate than any place else? Could it be they don't give up as quickly as other doctors do? Russian doctors are predominately women. Could they be more inclined to figure out this predominately women's disorder? This study was done in 1986.[Erythema nodosum in the clinical picture of internal diseases] [Article in Russian] Tareev EM, Kornev BM, Moiseev SV. A study of 64 patients with erythema nodosum (EN), including 53 females, showed sarcoidosis diagnosed in 65% of the cases to be the principal cause of EN. It was followed by drug disease (10%), tuberculosis (3%), pregnancy or labor (5%), tumors (3%) and other underlying diseases (Behcet's diseases, streptococcal infection, histoplasmosis, nonspecific aorto-arteritis, chronic active hepatitis). The cause of EN could not be

identified in 5% of patients only. Two or three possible etiologic factors were identified in 17%. Sarcoidosis combined with EN regressed without treatment in 82% of cases. Corticosteroid therapy was only given in cases of pulmonary lesion or other systemic manifestations. Purposeful investigation is believed to be capable of establishing etiology of EN in virtually all cases.Please enter Erythema Nodosum.........Thanks!Donation Information