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Metallic Sensitivity Test

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Forwarded by from http://www.medscape.com.

Comment: This test is done in Sweden and

Germany and Belgium. It is a

medical Lab test that will be

coming to Maine(U.S.A.) early in

2001. I was thinking about confirming a VEGA test that showed high mercury

immune response by sending my blood to Sweden. Either way I get the

fillings out.

Rod

UI - 96401635

TI - Mercury-specific lymphocytes: an indication of mercury allergy in man.

SO - J Clin Immunol 1996 Jan;16(1):31-40

TA - J Clin Immunol

VI - 16

IP - 1

PG - 31-40

DP - 1996

AU - Stejskal VD

AU - Forsbeck M

AU - Cederbrant KE

AU - Asteman O

AD - Astra AB, Safety Assessment, Sodertalje, Sweden.

AB - In this study, 18 patients with oral lichen planus (OLP), adjacent to

amalgam fillings, were tested in vitro with an optimized lymphocyte

proliferation test, MELISA (memory lymphocyte immunostimulation assay) and with

a patch test. Twenty subjects with amalgam fillings but without oral discomfort

and 12 amalgam-free subjects served as controls. The results show that patients

with OLP have significantly higher lymphocyte reactivity to inorganic mercury, a

corrosion product of amalgam, compared to control groups. Removal of amalgam

fillings resulted in the disappearance of oral mucosal changes, thus indicating

a causal relationship. Positive responses to phenylmercury (phenyl-Hg), a

bactericidal agent in root fillings and in pharmaceutical preparations, were

also noted in the oral lichen group but not in the control groups. Thus,

low-grade chronic exposure to mercury may induce a state of systemic

sensitization as verified by Hg-specific lymphocyte reactivity in vitro.

IS - 0271-9142

MJ - Dental Amalgam [adverse effects]

MJ - Hypersensitivity [immunology]

MJ - Lymphocytes [immunology]

MJ - Mercury [immunology]

MN - Adolescence

MN - Adult

MN - Immunologic Memory

MN - Lichen Planus, Oral [immunology]

MN - Lymphocyte Transformation [drug effects]

MN - Lymphocytes [drug effects]

MN - Mercury [pharmacology]

MN - Middle Age

MN - Skin Tests

RN - 7439-97-6 (Mercury); 8049-85-2 (Dental Amalgam)

MT - Female; Human; Male

LA - English

PT - JOURNAL ARTICLE

EM - 199701

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