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Re: Crinone/ Progesterone build-up

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I am learning so much in just my first day in this group! This explains to me

what

happened to me a year ago when I tried the Crinone 4% vaginal gel (progesterone)

for only

one cycle. After using the Crinone, I began having uterus cramps and a non-stop

migraine.

After quitting the Crinone 2 days early, the cramps stopped, but the migraine

continued

on for two months. (I threw out the Crinone and never used it again.) Then I

started to

have hot flashes again, which hadn't happened for the last 10 years that I was

taking 1 mg.

estradiol per day. After the hot flashes started, I finally recognized that

" something " was

blocking my estrogen receptors, and I started to up my dose of estrogen until I

reached

the dose that stopped my migraine. The dose was twice as much as I had been

using. Now,

even one year later, I still need 2 mg. estradiol per day instead of the 1 mg.

per day that

was sufficient for me for 10 years.

Until now, I couldn't understand why using the Crinone was still affecting me

one year

later. And Crinone is supposed to be a low 20 mg. per day dose! Can I assume

that most

of you are taking the natural progesterone orally, as in Prometrium or a

compounded

capsule? Estradiol doesn't seem to build up in the skin, but progesterone must,

so I guess

progesterone creams are out?

>

>

> Shinta,

>

> After several months on the high dose progesterone in the Wiley Protocol,

> many of us began to feel that the progesterone was " stuck " in our tissues, and

> that it had built up over the months.

>

> Dr. Bent Formby (check the _www.rhythmicliving.com_

> (http://www.rhythmicliving.com) website) found the research showing this was

true.

Unlike estrogen

> which gets used up quickly, progesterone can stay in the tissues for a long

> time. Only half of the progesterone taken in will be used in approximately

four

> Dr. Magaziner, former ACAM President and anti-aging doctor, confirmed our

> observations about progesterone build-up in 2005.

>

> Many women write to this group asking what to do about their

> progesterone-caused water retention and weight gain. I'm sorry to say, we

don't know

how to

> safely get the excess progesterone out of the tissues. As you can see, some

> are experimenting with detox methods.

>

> There are a few women who seem to escaped progesterone toxicity. We can only

> speculate that they were poor absorbers of the cream since according to Dr.

> Zava, absorption can vary by a factor of 30-fold. The poor absorbers are

> lucky!

>

> I wish we could help you more. We can only warn women.

>

> Lynne

>

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