Re: Relapse after starting

[Guest guest]

Many people go through feeling old symptoms come up. It is as if your body

is working through it while it heals. Some people even feel the symptoms

quickly going backwards, as if you go in reverse from what order your

symptoms had come in the first place. I hope that is all that you are going

through. Keep us posted on how you are feeling. Hopefully it will work its

way through quickly.

If not, look into reducing the dosage or changing the filler. My husband

had new areas of numbness and tingling until he went down to 3.0 from 4.5mg

Kindest of regards

Aletha

[low dose naltrexone] Relapse after starting

> Hi Guys,

>

> I have MS and just started taking 3.0 LDN 11 days ago. After the

> fifth day, I went into a full blown exasurbation, and I am still there

> 6 days later. I was just wondering if anyone else has experienced

> this, and how long did it last for you? I am hopeful, and hanging in

> there until this one passes! Prayers for everyone out there going

> through the same thing!!!

>

>

>

>

>

>

>

>

>

[Guest guest]

>

> Hi Guys,

>

> I have MS and just started taking 3.0 LDN 11 days ago. After the

> fifth day, I went into a full blown exasurbation, and I am still

there

> 6 days later. I was just wondering if anyone else has experienced

> this, and how long did it last for you? I am hopeful, and hanging

in

> there until this one passes! Prayers for everyone out there going

> through the same thing!!!

>

=============

For those of you in the first 3 months of LDN therapy Dr. Bob

Lawrence from the UK who has MS & uses LDN himself explains why the

temporary increase in MS symptoms upon starting LDN. The increased

symptoms are not lasting for 3 months generally but usually take

place during the 1st 3 months.

When starting this LDN(Low Dose Naltrexone) therapy in the treatment

of MS, there may also be some initial transient, though temporary,

increase in MS symptoms.

Experience in using this method has demonstrated most commonly, such

as disturbed sleep, occasionally with vivid, bizarre and disturbing

dreams, tiredness, fatigue, spasm and pain. These increased symptoms

would not normally be expected to last more than seven to ten days.

Rarely, other transient symptoms have included more severe pain and

spasm, headache, diarrhea or vomiting. These additional symptoms

would appear to be associated with the previous frequent use of

strong analgesics, which effectively create an addiction and

dependency, thus increasing the body's sensitivity to pain. This

temporary increase in symptoms may also perhaps be explained when we

consider the manner in which this drug is expected to work.

Initially, MS occurs due to a reduction in the activity of the

controlling influence of the suppressor T-cells within the immune

system. During an acute relapse, the overall number of T-cells is

reduced, the normal balance of helper T-cells and suppressor T-cells

is disrupted and the damaging helper (CD-4) T-cells tend to

predominate. This is the situation most pronounced during an acute

relapse but occurs similarly, but to a lesser extent, in chronic

progressive MS. Under the influence of LDN there will be an expected

increase in the overall numbers of T-cells but, because the CD-4,

helper T-cells tend to predominate at this time, an increase in their

numbers will expectedly tend to increase MS symptoms. It is only when

the numbers of suppressor T-cells effectively " catch up " that the

normal balance is restored and symptoms once again diminish and

improve.

In addition, because LDN stimulates the immune system and many of the

drugs routinely used by the NHS in the treatment of MS further

suppress the immune system, LDN cannot be used in company with

steroids, beta interferon, methotrexate, azathioprine or mitozantrone

or any other immune suppressant drug. If there is any doubt, please

submit a full list of the drugs you are presently taking so that

their compatibility may be assessed.

In addition, because LDN will also block the analgesic effects of any

opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine

or diamorphine) presently being taken, the use of LDN will initially

greatly increase the level of pain experienced. It is therefore

advisable that any opiate-like drugs be discontinued at least two

weeks before this treatment is initiated. When starting the treatment

it is essential that any untoward or adverse side-effects are

reported immediately so that the treatment process can be further

assessed and, if necessary, modified.

Dr. M R Lawrence

posted by

[Guest guest]

--- In low dose naltrexone , " lmauro143 " <lmauro143@y...>

wrote:

>

> Hi Guys,

>

> I have MS and just started taking 3.0 LDN 11 days ago. After the

> fifth day, I went into a full blown exasurbation, and I am still

there

> 6 days later. I was just wondering if anyone else has experienced

> this, and how long did it last for you? I am hopeful, and hanging in

> there until this one passes! Prayers for everyone out there going

> through the same thing!!!

>

Hi, I am only on 1.75 and am having my old symptoms return off and on.

I think I am around day 7. After taking it at night my eyes shift back

and forth can't sleep well and felt like I ws going to throw up last

night. Mabey lower your dose so your body isn't " shell shocked " and

work your way up to 3 after a few weeks. I'm not sure as i am having

trouble too. good luck. I hate those relapses!!!