LDN and Weight Loss

[Guest guest]

Hi –

You've mentioned several times that you believe LDN helps some

people lose weight because it " is a diuretic " and that it " pulls

fluid off you. "

I think you may have been misinformed. Naltrexone isn't a

diuretic. In fact, it's sometimes used to counteract the diuretic

effect of other substances. For example:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=6121047 & dopt=Abstract

Naltrexone does have an established connection to weight loss.

Loss of appetite is a recognized side-effect. Studies have been

conducted on naltrexone for obesity, especially sweets-cravings and

binge-eating. Opioid antagonists like naltrexone are associated

with a reduction in food cravings and a subsequent reduction in food

intake.

Yale is currently conducting a clinical study to see if naltrexone

can help smokers quit without gaining weight:

http://www.yale.edu/opa/newsr/05-02-28-02.all.html

I know you said your grandmother's ankles were less swollen after

starting LDN, and I don't mean to be a nitpicker, but I think it may

be misleading to assume that LDN is a diuretic for everyone who

takes it.

I lost 10 pounds, but it wasn't water weight. I've always been thin;

now I'm just thinner. : )

Maureen (Gazorpa)

[Guest guest]

>

> Hi –

>

> You've mentioned several times that you believe LDN helps some

> people lose weight because it " is a diuretic " and that it " pulls

> fluid off you. "

>

> I think you may have been misinformed. Naltrexone isn't a

> diuretic. In fact, it's sometimes used to counteract the diuretic

> effect of other substances. For example:

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> cmd=Retrieve & db=PubMed & list_uids=6121047 & dopt=Abstract

>

> Naltrexone does have an established connection to weight loss.

> Loss of appetite is a recognized side-effect. Studies have been

> conducted on naltrexone for obesity, especially sweets-cravings and

> binge-eating. Opioid antagonists like naltrexone are associated

> with a reduction in food cravings and a subsequent reduction in

food

> intake.

>

> Yale is currently conducting a clinical study to see if naltrexone

> can help smokers quit without gaining weight:

>

> http://www.yale.edu/opa/newsr/05-02-28-02.all.html

>

> I know you said your grandmother's ankles were less swollen after

> starting LDN, and I don't mean to be a nitpicker, but I think it

may

> be misleading to assume that LDN is a diuretic for everyone who

> takes it.

>

> I lost 10 pounds, but it wasn't water weight. I've always been

thin;

> now I'm just thinner. : )

>

> Maureen (Gazorpa)

>

===============

Where I'm getting this is the numerous people who have had increased

urination in the early stages of LDN. I have a new lady on my board

running to the bathroom 4 to 5 times at night upon starting LDN and

she wasn't doing this before. I had a man on my site who had a

severe increase in urinary frequency on LDN so bad that he was

thinking of stopping LDN. Another woman on my site went through the

same and a few here noticed urinary frequency increasing upon

starting LDN. Quite a few on my board in past have had this increase

in urinary frequency and weightloss right in the very beginning days

of LDN and some at GoodShape's have had the same results. The

weightloss is taking place in the first week to 10 days on LDN so

that's why I feel it is having a diuretic effect. There was a

discussion at GoodShape's long ago about this and everyone who had

lost 5 to 10 pounds on LDN in the first 10 days of starting LDN were

still eating like they always had and those who had lost weight and

wanted to put their weight back on tried over-eating with zero

results and I think GoodShape was one of them. So something is

happening in the first 10 days on LDN to pull weight off people and

it's not suppression of appetite. I've noticed those who've had the

heavy urinary flow in the early days of LDN who have high blood

pressure, that many with high BP had their BP go down slightly due to

all the urination and weight loss. I know my grandma's ankles went

down in three days on LDN and we were eating out at that time and she

was eating large portions of icecream twice per day at the hotel

restaurant we were staying at.

Would be interesting to do a poll on how many had urinary frequency

upon starting LDN and if their weightloss was within the first 10 to

14 days on LDN and if they had a decrease in appetite at that time

and have they tried eating more to see if they could put back on the

weight lost. How many had fluid on their ankles before LDN and if

LDN took the fluid off, how many days from start of LDN did it take

for fluid to reduce. And what dose of LDN did they start with.

The lady on my forum only started with 1.5mg and it's running her to

the toilet many times at night after she takes her LDN dose, not

before the LDN dose.

[Guest guest]

I am on a gluten-free diet for 3 years now and on a strict BBD for more than one year. After one month on the BBD I had lost 4 pounds and after one more month another 2 pounds. I was thin to begin with, so I didn't have what to lose. I tried to eat more and gradually regained my 2 pounds. From then and on, my weight was stabilized -4 pounds and my colitis disappeared. I started LDN almost five months ago - no weight change. In my case the loss of weight was due to the BBD. A nutritionist told me that gluten and lactose may be blocking one's metabolism, so when you stop having them your metabolism works faster.

Best wishes

Katerina

[Guest guest]

My weight loss stabalized after about 6 months. I was thin to start with and lost about 6 lbs.

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