Progesterone and growth hormone

[Guest guest]

Growth hormone and progesterone. During pregnancy progesterone suppresses growth hormone.  That's good in pregnancy otherwise the fetus could get too big.  It doesn't take much progesterone to suppress growth hormone.  You can get this tested by using several methods, but most use serum  IGF1 to look at growth hormone.  I buy requisitions from www.lef.org and go over to a Labcorp facility.  If you've been on high P it is good to know what it's done to your IGF1.  I track it over time to see if the damaging effects of the protocol are subsiding.   If anyone tells me they are dong well on the protocol I want to see the IGF1 levels - for a start.   LG (in the stories on the webpage) wrote  "My IGF-I is below reference range."On page 81 of Vliet's Screaming To Be Heard. "The broad suppressive effects of progesterone (and progestins derived from it) on pituitary gonadotropin, ATCH, and GH release suggest that progesterone produced by the placenta is one of the major ways the pregnant body shifts its endocrine "manager" from pituitary control to control by the placental as the baby grows.Again on page 80 and 81 of Screaming to Be Heard, Dr. Vliet says that too much progesterone interferes with GH release. She quotes a study by *(see reference below)"Bhatia where they found that a daily oral dose (300-400 mg of P) caused significant blunting of GH concentrations in all patients, as well as produced the unwanted effect of significant rises in insulin levels and an exaggerated (abnormal) response of insulin to oral glucose. The rising levels of insulin also caused further decreased in GH release. The hypothesis was that progesterone decreased plasma levels of GH by a suppressant effect of the central nervous system, rather than by direct action on the pituitary cells that synthesize it."More Vliet, "Women in Bhatia's study were only given progesterone for a week." Vliet points out that 100mg of oral should be converted to 10mg/gram of cream. What would that be in terms of lines if we get 25mg/line?She also refers to studies that show high levels of progesterone in the mid luteal phase of the menstrual cycle suggest that an elevated progesterone-to-estradiol ratio exerts a catabolic (breakdown) effect on body proteins. If this effect continues to be supported by future studies it would suggest that women with muscle pain syndrome should be cautious about using progesterone on a regular basis to avoid any excess breakdown of protein and muscle tissue. Vliet SBTH Pg 97-98 Laurelwww.rhythmicliving.orgReference for the comments about GHJ Clin Endocrinol Metab. 1972 Sep;35(3):364-9.Related Articles, LinksProgesterone. Suppression of the plasma growth hormone response.Bhatia SK, D, Kalkhoff RK.***There are doctors prescribing the Wiley Protocol who did not know that there is a difference between oral and transdermal progesterone.  Out of respect for accuracy I think it best that we refrain from calling the Wiley Protocol doctors researchers.  

[Guest guest]

Hi, Laurel, The IGF-1 blood test seems like a prudent thing for people like me, who are taking Wiley levels of progesterone (even without bad symptoms), to get done. I am also an LEF member and looked up the test on their site: there are two of them (as below) and I wonder whether you or anyone might know about the usefulness of the second one as well (not much info about it was provided). Interesting-- I've had a stressful time these last few months, and a friend recommended I take HGH to sleep better, which seems to have helped some. Makes me wonder. Jesa IL-6/IGF-1 This test is used to evaluate levels of Insulin-Like Growth Factor I and Interleukin-6. Research investigating DHEAS levels found that that IGF-I was positively correlated to DHEAS levels and IL-6 levels were negatively correlated to DHEAS levels. Insulin-Like Growth Factor

I (IGF-1) This test is used to determine acromegaly, in which Sm-C and GH are increased. It is also used to evaluate hypopituitarism. Somatomedin-C is a polypeptide hormone produced by the liver and other tissues, with effect on growth promoting activity and glucose metabolism (insulin-like activity). Somatomedin-C is carried in blood bound to a carrier protein which prolongs its half-life. Its level is therefore more constant than that of growth hormone. Low values are described with advanced age. Low values may indicate hypopituitarism, malnutrition, diabetes mellitus, Laron dwarfism, hypothyroidism, maternal deprivation syndrome, pubertal delay, cirrhosis, hepatoma, and some cases of short stature and normal GH response to pharmacologic tests. Low values may be found with nonfunctioning pituitary tumors, with constitutional delay of growth and development and with anorexia nervosa. High values occur with adolescence, true precocious puberty, pregnancy, obesity, pituitary gigantism, acromegaly and diabetic retinopathy. Since Sm-C is decreased with malnutrition, its concentration provides an index with which to monitor therapy for food deprivation. INTERKEUKIN 6 (IL-6)This test is used to identify evaluated levels of Interleukin-6. IL-6 is a cytokine produced by many different cells including monocytes/macrophages, fibroblasts, endothelial cells, keratinocytes, mast cells, T cells and many tumor cell lines. Elevated IL-6 serum or plasma levels may occur in different conditions including sepsis, autoimmune diseases, lymphomas, AIDS, alcoholic liver disease, tumor development, Alzheimer’s disease, and in individuals with infections or transplant rejection. Elevated levels of IL-6 may be associated with an increased risk of heart attack, and stroke. INSULIN LIKE GROWTH

FACTOR BINDING PROTEIN (IGFBP-3) Elevated levels in hypertensive individuals have been associated with a nine-fold increase of carotid arteriosclerosis. Laurel wrote: Growth hormone and progesterone. During pregnancy progesterone suppresses growth hormone. That's good in pregnancy otherwise the fetus could get too big. It doesn't take much progesterone to suppress growth hormone. You can get this tested by using several methods, but most use serum IGF1 to look at growth hormone. I buy requisitions from www.lef.org and go over to a Labcorp

facility. If you've been on high P it is good to know what it's done to your IGF1. I track it over time to see if the damaging effects of the protocol are subsiding. If anyone tells me they are dong well on the protocol I want to see the IGF1 levels - for a start. LG (in the stories on the webpage) wrote "My IGF-I is below reference range."On page 81 of Vliet's Screaming To Be Heard. "The broad suppressive effects of progesterone (and

progestins derived from it) on pituitary gonadotropin, ATCH, and GH release suggest that progesterone produced by the placenta is one of the major ways the pregnant body shifts its endocrine "manager" from pituitary control to control by the placental as the baby grows.Again on page 80 and 81 of Screaming to Be Heard, Dr. Vliet says that too much progesterone interferes with GH release. She quotes a study by *(see reference below)"Bhatia where they found that a daily oral dose (300-400 mg of P) caused significant blunting of GH concentrations in all patients, as well as produced the unwanted effect of

significant rises in insulin levels and an exaggerated (abnormal) response of insulin to oral glucose. The rising levels of insulin also caused further decreased in GH release. The hypothesis was that progesterone decreased plasma levels of GH by a suppressant effect of the central nervous system, rather than by direct action on the pituitary cells that synthesize it."More Vliet, "Women in Bhatia's study were only given progesterone for a week." Vliet points out that 100mg of oral should be converted to 10mg/gram of

cream. What would that be in terms of lines if we get 25mg/line?She also refers to studies that show high levels of progesterone in the mid luteal phase of the menstrual cycle suggest that an elevated progesterone-to-estradiol ratio exerts a catabolic (breakdown) effect on body proteins. If this effect continues to be supported by future studies it would suggest that women with muscle pain syndrome should be cautious about using progesterone on a regular basis to avoid any excess breakdown of protein and muscle tissue. Vliet SBTH Pg 97-98 Laurelwww.rhythmicliving.orgReference for the comments about GHJ Clin Endocrinol Metab. 1972 Sep;35(3):364-9.Related Articles, LinksProgesterone. Suppression of the plasma growth hormone response.Bhatia SK, D, Kalkhoff RK.***There are doctors prescribing the Wiley Protocol who did not know that there is a difference between oral and transdermal progesterone. Out of respect for accuracy I think it best that we refrain from calling the Wiley Protocol doctors researchers.

Sponsored LinkGet an Online or Campus degree - Associate's, Bachelor's, or Master's -in less than one year.