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Biol Trace Elem Res. 1994 Jul;42(1):63-70. Related Articles, Links The antioxidant enzymes activity in the conditions of systemic

hypersilicemia.Najda J, Goss M, Gminski J, Weglarz L, Siemianowicz K, Olszowy Z.Department of Internal Diseases, Silesian Medical Academy, Katowice, Poland.The effect of an excessive inorganic silicon oral intake on the activity of basic antioxidant enzymes was studied in rats. Activities of superoxide dismutase, catalase, and glutathione peroxidase were measured in liver and kidney tissues of animals receiving per os sodium metasilicate nonahydrate (Na2SiO3.9H2O) (Sigma, [st. Louis, MO]) dissolved in their drinking water. A decrease of the activity of all the studied enzymes was found in the samples derived from the experimental group. The

results obtained indicate the free oxygen radicals participation in the potential pathologic events in the conditions of systemic hypersilicemia.PMID: 7986662 [PubMed - indexed for MEDLINE]

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