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Where does one buy gets more info or could buy this new thing from?Regards.PierreTo: mb12 valtrex From: laurad121@...Date: Wed, 17 Dec 2008 00:38:53 +0000Subject: Re: What is OSR

OSR is a new Antioxidant that is a highly purified, safe, non-toxic

nutritional supplement that scavenges harmful free radicals aiding the

body to restore its own detoxifying capability.

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>

> OSR is a new Antioxidant that is a highly purified, safe, non-toxic

> nutritional supplement that scavenges harmful free radicals aiding

the

> body to restore its own detoxifying capability.

Where do you purchase this

>

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Found this from the makers of OSR. It is worth the read.- Val

What is OSR?

OSR stands for Oxidative Stress Relief. OSR, a patented new discovery,

is a safe and non & #8208;toxic nutritional supplement that dramatically

reduces oxidative stress by significantly increasing glutathione in

its " reduced form " called GSH. The increased amount of GSH, or reduced

glutathione, allows the body to scavenge

harmful free radicals and restore its own detoxifying mechanisms. OSR

has been shown to elevate glutathione levels most likely due to its

positive ORAC score (Oxygen Radical Absorbance Capacity) and the fact

that it is more li

pid soluble than other hydroxyl radical scavengers. This is how it

works: OSR scavenges free radicals leading to an increase of reduced

glutathione, or GSH, inside the cells. The increased levels of GSH can

then be used to detoxify the body of toxins through the attachment of

GSH by an enzyme known as Glutathione & #8208;S & #8208;Transferase. Toxins, tightly

bound and rendered inert, are processed through the liver and then

leave the body safely through the liver or biliary

system. OSR is a unique supplement for restoring and maintaining good

health from exposure to pollutants, toxins and heavy metals and other

sources that produce dangerous free radicals causinitions in the body.

g numerous harmful cond

What is Oxidative Stress? Oxidative Stress is a condition that occurs

when the available supply of antioxidants, the body's defense

mechanisms, is not sufficient to handle and neutralize free radicals,

potentially harmful and unstable molecules formed when weak bonds

split leaving the molecules with an odd, unpaired electron. The

resulting condition – oxidative stress – can create massive cell

damage that can result in cellular mutations, tissue breakdown, immune

compromise and a host of other harmful conditions and disorders.

What are Reactive Oxygen Free Radicals?

Reactive oxygen free radicals are highly unstable oxygen & #8208;containing

molecules that interact quickly and aggressively with other molecules

in our bodies to oxidize them and inhibit their biological activity.

Free radicals are capable of modifying the proteins, enzymes and

lipids of membranes, as well as penetrating into the DNA of a cell and

damaging the genome. Excess free radicals also damage mitoch

ondria, the leading energy producing organel of the cell. Free

radicals are unstable because they have unpaired electrons in their

molecular structure. This instability causes them to react almost

instantly with any substance in their vicinity. This process is called

an " oxidation reaction. "

How do Free Radicals relate to Antioxidants, Oxidative Stress and

Human Health?

Oxidation reactions are crucial for life, but they can also be

damaging. In fact, oxygen, or hydroxyl free radicals are especially

dangerous. Oxidative stress occurs when the production of hydroxyl

free radicals exceeds the body's natural antioxidant defense

mechanisms, causing damage to DNA, proteins, and lipids. To survive,

plants and animals have developed complex systems with multiple types

of antioxidants, such as glutathione, Vitamin C, Vitamin E, and

enzymes, that either prevent oxidative stress caused by free radicals

or by removing free rad

icals before they can damage important parts of the cell. Free

radicals can play a useful role in our body. Some free radicals, for

example, form normally during metabolism. The body's immune system can

purposefully create them to neutralize viruses and bacteria. The

detoxifying actions of the liver also require free radicals to

complete the critical process of ridding the body of

organic based toxins like pesticides and herbicides. Although useful

under controlled conditions, free radicals are extremely unstable and

can damage cells if left uncontrolled as caused by infections and

toxic exposures. Free radicals destroy cellular membranes, enzymes,

and DNA. For example, inflammation is usually a site of high free

radical production as the body's immune system fights an infection.

The result of excessive amounts of unstable, uncontrolled and

aggressive free radicals in the body causes the condition known as

oxidative stress.

Oxidative stress chips away at healthy cells and is a process,

scientists know, that contributes to a host of diseases and conditions

in humans ranging from rheumatoid arthritis, Alzheimer's Disease,

heart disease and stroke to cancer and aging process. It has also been

linked to autoimmune diseases and autism. In fact, researchers at the

University of Pennsylvania School of Medicine have discovered that

children with autism showed signs of abnormal blood-vessel function

linked with damaging levels of oxidative stress as compared to healthy

children.

What are sources of Free Radicals ? Among many other sources, free

radicals are released in the body from exposure to pollutants, toxins

and heavy metals, such as mercury and lead. Inflammation caused by

toxins and infections also increase free radical production.

Free radicals are also released in the body in response to a number of

toxins, including, pesticides, alcohol, radiation, and smoking.

Smoking leads to emphasema as the immune system detects tobacco toxins

and produces free radicals in an attempt to kill

the perceived infection.

Psychological and emotional stress, or even intensive workouts by

athletes, can result in the release of free radicals and can

contribute to oxidative stress. That is because, when the body is

under stress, it produces certain hormones that generate free

radicals. Thereafter, the liver must eventually detoxify them and that

process also generates free radicals. While everyone is exposed to

free radicals from a multitude of sources, those living in cities are

exposed at much higher levels due to a greater degree of pollutants

and toxins in urban environm

ents.

Glutathione:

The Body's Pivotal Mechanism to Reduce Oxidative Stress The body

maintains a sophisticated system of chemical and biochemical defenses

to control and neutralize free radicals. There are two groups of antioxi

dants: chemical antioxidants and biochemical antioxidants. Chemical

antioxidants scavenge free radicals, that is, they stabilize the

unstable free radicals by giving them the electron they need to " calm

down. " The antioxidants are usually consumed or used up in this

process, that is, they sacrifice themselves. Among the most important

chemical antioxidants are glutathione, Vitamins A, E and C, selenium,

and zinc. Vitamin C is known to increase reduced glutathione by

increasing NADPH levels which then convert oxidized glutathione (GSSG)

to reduced glutathione (2 GHSs) by a process called the Meister cycle.

Biochemical antioxidants not only scavenge free radicals but also

inhibit their formation inside the body. They include lipoic acid,

melatonin, and cholest

erol. Of all the antioxidants, glutathione appears the most pivotal in

reducing oxidative stress. Made up of three amino acids (cysteine,

glycine and glutamic acid), glutathione is a substrate of the

antioxidant enzyme, glutathione peroxidase, and is the mo

st important because it is critical in removal of toxins in the liver.

While all cells in the human body are capable of synthesizing

glutathione, glutathione synthesis in the liver has been shown to be

most essential in processing toxins o

ut of the body through the P450 detox system of the liver or biliary

system. Glutathione exists in two forms: the reduced state (GSH) and

the oxidized or

disulfide state (GSSG). In healthy cells and tissue, more than 90% of

the total glutathione level is in the reduced form (GSH) and less than

10% exists in the oxidized state (GSSH). The oxidative stress

condition is usually monitored by easuring the level of glutathione

and the reduced glutathione/oxidized glutathione atios by CLIA

approved laboratories.

mr

Low levels of glutathione are typically found in people diagnosed with

many illnesses including rheumatoid arthritis, AIDS, cancer,

Parkinson's Disease, immune disorders, and in children diagnosed with

autism, as well as with many other conditions. Adults and children

with these conditions are typically found to have insufficient levels

of antioxidants to fight against high levels of free radicals being

produced, a circumstance that causes oxidative stress. It is no

surprise, then, that persons with these conditions arre oxidative stress.

e found to have seve

The Benefits of OSR OSR is a safe and non & #8208;toxic nutritional supplement

that dramatically reduces oxidative stress by significantly increasing

the level of glutathione in most, if not all, cells. Glutathione is

the pivotal liver detoxifying antioxidant, thereby allowing the body

to remove harmful free radicals and restore its own protective

mechanisms. OSR is not a precursor for glutathione synthesis and most

likely elicits its effect of increasing reduced glutathione by its

ability to scavenge hydroxyl radical species within

the lipophilic aspects of the cells and mitochondria. OSR is a newly

patented supplement that aids in restoring and maintaining good health

from exposure to pollutants, heavy metals and other toxic sources that

produce dangerous free radicals resulting in numerous harmful

conditions in the

body. Current information available from CTI Science Inc (as of 8/16/08),

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