Platinum concentration in silicone breast implant material and capsular tissue by ICP-MS

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Analytical and Bioanalytical Chemistry

Publisher: Springer-Verlag Heidelberg

ISSN: 1618-2642 (Paper) 1618-2650 (Online)

DOI: 10.1007/s00216-004-2714-y

Original Paper

Platinum concentration in silicone breast implant

material and capsular tissue by ICP-MS

S. V. M. Maharaj

(1) Department of Chemistry, American University,

Washington, DC 20016, USA

Received: 5 January 2004 Revised: 28 May 2004

Accepted: 7 June 2004 Published online: 8 July 2004

Abstract Inductively coupled plasma-mass spectrometry

(ICP-MS) was used to determine the concentration of

platinum (Pt) in silicone breast implant gel (range,

0.26?48.90 g g?1 Pt; n=15), elastomer (range,

3.05?28.78 g g?1 Pt; n=7), double lumen (range,

5.79?125.27 g g?1 Pt; n=7), foam (range, 5.79?8.36 g

g?1 Pt; n=2), and capsular tissue (range, 0.003?0.272

g g?1 Pt; n=15). The results show that very high

levels of Pt are present in the encasing elastomer,

double lumen, and foam envelope materials. Silicone

breast implants can be a source of significant Pt

exposure for individuals with these implants.