CEN: Study implicates silicone implants as source of harmful platinum species

[Guest guest]

Thanks Ilena, The word about platinum is spreading !

Glory!

Personally, I feel the dam has broken and things are

going to change forever! - Rogene

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http://pubs.acs.org/cen/news/84/i16/8416platinum.html

> April 10, 2006

> CLINICAL CHEMISTRY

> Platinum From Breast Implants

> Study implicates silicone implants as source of

> harmful platinum species

> Mitch y

> Women with silicone breast implants are likely to

> have higher concentrations of harmful forms of

> platinum in their bodies than women who have never

> had implants, according to a new study (Anal. Chem.,

> published online April 1,

> dx.doi.org/10.1021/ac0514016). A key finding of the

> investigation, which probed the levels and oxidation

> states of the metal, is that platinum species remain

> in the body long after the implants have been

> removed.

>

> EXPERTOX PHOTO

> In The Lab Lykissa uses chromatography and

> mass spectrometry methods to quantify platinum

> concentrations in clinical samples.

>

>

>

> One of the steps in preparing medical-grade silicone

> (polydimethylsiloxane) is cross-linking the polymer

> chains to control the material's stiffness and

> viscosity. The process calls for a cross-linking

> catalyst such as hexachloroplatinate, which is

> implicated in the study as the source of the metal.

>

> The study's authors note that exposure to platinum

> species with oxidation states other than zero is

> believed to be harmful to human health. In

> particular, exposure to platinum salts has been

> associated with neurotoxicity, carcinogenicity, and

> other harmful effects, they say.

>

> To assess the concentrations of platinum, Ernest D.

> Lykissa, a forensic toxicologist at ExperTox, Deer

> Park, Texas, and V. M. Maharaj of the Center

> for Research on Environmental Medicine, New Market,

> Md., analyzed samples of tissues and body fluids

> from some 20 subjects with breast implants by ion

> chromatography-inductively coupled plasma mass

> spectrometry. The subjects included women of various

> ages who had had the implants for as long as 25

> years. Most of the subjects had had the implants

> removed-some shortly before the study and others

> several years before. Control subjects who never had

> breast implants were also studied.

>

> On the basis of the investigation, the team

> concludes that platinum concentrations in

> breast-implant subjects are much higher than in

> women with no known exposure to platinum. In urine,

> for example, the researchers found an average of

> approximately 2 µg of platinum per gram of

> creatinine, which is 60 to more than 1,700 times

> higher than that of the general population. In

> breast milk, hair, and nails, they found the

> platinum concentrations to be higher by factors of

> 100, 14, and three, respectively. They add that in

> implant subjects, platinum was found primarily in

> reactive forms, including +2, +4, and +6 oxidation

> states.

>

> Chemical & Engineering News

> ISSN 0009-2347

> Copyright © 2006 American Chemical Society

> ~~~

> www.BreastImplantAwareness.org/CANDO.htm

[Guest guest]

>Personally, I feel the dam has broken and things are

going to change forever! - Rogene

From your fingers to God (and the FDA's) ears Rogene!

www.BreastImplantAwareness.org/CANDO.htm