Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults

April 3, 2006

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Diet Rich in Magnesium May Reduce the Risk of Metabolic Syndrome

“Magnesium Intake and Incidence of Metabolic Syndrome Among Young

Adults,” He K, Liu, K, et al, Circulation, 2006, Vol. 113 [Epub ahead of

print]. (Address: Dr. Ka He, Department of Preventive Medicine, Feinberg

School of Medicine, Northwestern University, Chicago, Illinois, USA.

E-mail: kahe@... ).

Summary: In a prospective study involving 4,637 young adults between

the ages of 18 and 30 years, dietary intake of magnesium was found to be

associated with a reduced incidence of metabolic syndrome. Subjects

enrolled in the study were free of the metabolic syndrome and diabetes

at baseline. Diet was assessed via an interviewer-administered

quantitative food frequency questionnaire, and the amount of dietary

magnesium consumed was derived using the Minnesota Nutrition

Coordinating Center’s nutrient database. Over the course of a 15 year

follow-up, 608 subjects developed the metabolic syndrome, diagnosed

according the definition set forth by the National Cholesterol Education

Program/Adult Treatment Panel III. Analysis of the data, after adjusting

for major lifestyle and dietary confounding factors, revealed an inverse

relationship between magnesium intake and incidence of metabolic

syndrome. The multivariable-adjusted hazard ratio of metabolic syndrome

was 0.69 for subjects in t he highest versus the lowest quartile of

magnesium intake, irrespective of race or sex. Subjects with a higher

intake of magnesium also had a reduced incidence of the individual

components of the metabolic syndrome, including fasting insulin levels,

as compared to subjects with a lower intake of magnesium. These results

suggest that subjects who consume diets rich in magnesium may have a

significantly reduced risk (this study found a 31% reduced risk) of

developing the metabolic syndrome.

--

ne Holden, MS, RD < fivestar@... >

" Ask the Parkinson Dietitian " http://www.parkinson.org/

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