Influence of Coronary Artery Disease and Age on Homocysteine Levels

[Guest guest]

Colleagues, the following is FYI and does not necessarily reflect my own

opinion. I have no further knowledge of the topic. If you do not wish to

receive these posts, set your email filter to filter out any messages

coming from @nutritionucanlivewith.com and the program will remove

anything coming from me.

---------------------------------------------------------

Influence of Coronary Artery Disease and Age on Homocysteine Levels

Reference: “Influence of age and coronary artery disease on

homocysteine levels in the young old compared with the old old and the

oldest old,” Gravina CF, Batlouni M, et al, Am J Geriatric Cardiol,

2006; 15(3): 165-73. (Address: Dante Pazzanese Institute of Cardiology,

Sao o, Brazil. E-mail: cgtaddei@... ).

Summary: In a study involving 172 elderly subjects (aged 65 to over 80

years), levels of homocysteine were found to progressively increase with

increasing age among subjects diagnosed with coronary artery disease

(CAD). A similar such association was not found among subjects who were

free from coronary artery disease. Subjects, both those with a diagnosis

of CAD (‘cases’) and those free from CAD (‘controls’), were divided into

three groups based on age (65-74 years; 75-79 years; 80 years and

older). Coronary angiographies were performed and homocysteine levels

were measured. Levels of homocysteine above 14 mmol/L (considered

hyperhomocysteinemia), were found to be an independent risk factor for

CAD, with a risk ratio of 2.03. Homocysteine levels progressively

increased with increasing age among subjects with CAD. Continuous

homocysteinemia was associated with a risk ratio for CAD of 1.07 for

each mmol/L increase in homocysteine level. These results suggest that a

progressive in crease in homocysteine levels associated with increasing

age may be a pattern associated with the presence of CAD, and not a

normal consequence of aging.

--

ne Holden, MS, RD < fivestar@... >

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/