RE: Diets Low in Glycemic Load and Glycemic Index and High in Cereal Fiber May Increase Plasma Adiponectin Concentrations in Women with Type 2 Diabetes

July 18, 2006

what exactly is adiponectin?

________________________________

From: rd-usa on behalf of ne Holden, MS, RD

Sent: Tue 7/18/2006 8:06 AM

To: NCCMailList

Cc: Public Health Nutrition List; Food and Nutrition Specialists

Subject: Diets Low in Glycemic Load and Glycemic Index and High in

Cereal Fiber May Increase Plasma Adiponectin Concentrations in Women with Type 2

Diabetes

Colleagues, the following is FYI and does not necessarily reflect my own

opinion. I have no further knowledge of the topic. If you do not wish to

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Diets Low in Glycemic Load and Glycemic Index and High in Cereal Fiber

May Increase Plasma Adiponectin Concentrations in Women with Type 2 Diabetes

Reference: " Dietary fibers and glycemic load, obesity, and plasma

adiponectin levels in women with type 2 diabetes, " Qi L, Meigs JB, et

al, Diabetes Care, 2006; 29(7): 1501-5. (Address: Department of

Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston,

MA 02115. E-Mail: nhlqi@... ).

Summary: In a cross-sectional study involving 902 women with type 2

diabetes from the Nurses' Health Study, dietary intake of cereal fiber

and dietary glycemic load and glycemic index were associated with plasma

adiponectin; these associations were not modified by obesity status.

Dietary information was obtained from the subjects using

semiquantitative food frequency questionnaires. After adjusting for age,

smoking, alcohol consumption, physical activity, aspirin use, HbA(1c),

history of hypertension and hypercholesterolemia, and postmenopausal

hormone use, significant associations were found between intakes of

cereal and fruit fibers with an increasing trend of plasma adiponectin

concentrations. However, after adjusting further for body mass index

(BMI), the strength of the associations decreased for fruit fiber.

Adiponectin concentrations were 24% higher among women in the highest

quintile of cereal fiber intake, compared to women in the lowest

quintile. Additionally, after adj usting for BMI and other covariates,

dietary glycemic load and glycemic index were significantly associated

with lower plasma adiponectin levels. For dietary glycemic load,

adiponectin levels were 17% lower in the highest quintile than in the

lowest, while for dietary glycemic index, adiponectin levels were 18%

lower in the highest quintile than in the lowest. The positive

associations between dietary cereal fiber intake with plasma

adiponectin, and the inverse associations between dietary glycemic index

and glycemic load with plasma adiponectin, remained consistent across

lean (BMI less than 25 kg/m(2)), overweight (BMI between 25 to 30

kg/m(2)), and obese (BMI at least 30 kg/m(2)) subjects. Thus, this study

suggests that diets low in glycemic load and glycemic index and high in

cereal fiber may increase plasma adiponectin concentrations in women

with type 2 diabetes. Furthermore, the associations between dietary

cereal fiber intake, dietary glycemic load and glycemic i! ndex with

plasma adiponectin were not modified by obesity status.

--

ne Holden, MS, RD < fivestar@... >

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/

July 18, 2006

phew! and here i was thinkiong i was the only one who was wondering what that

was!

" Joyce, " wrote: