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Antidepressant and Lithium Therapy Linked to Future Use of Antiparkinson Drugs

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Colleagues, the following is FYI and does not necessarily reflect my own

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Antidepressant and Lithium Therapy Linked to Future Use of Antiparkinson

Drugs

http://www.medscape.com/viewarticle/536564?sssdmh=dm1.198229 & src=nldne

CME

Long-term Management of Psychotic Disorders: Road to Reintegration

* Review the clinical features of psychotic illnesses and analyze

the impact of established and newer pharmacotherapies on neurocognition.

Other CME programs»

NEW YORK (Reuters Health) Jun 16 - Treatment with antidepressants and

lithium is associated with an increased risk of later treatment with

antiparkinson drugs, according to findings from a Danish study.

The findings suggest that " patients with anxiety or affective disorders

are at increased risk of developing Parkinson's disease, " Dr. M.

Brandt-Christensen, from the University of Copenhagen, and colleagues note.

The study, reported in the Journal of Neurology, Neurosurgery, and

Psychiatry for June, involved an analysis of prescription data for

nearly 1.3 million people logged in a Danish national registry between

1995 and 1999.

Treatment with an antidepressant raised the risk of later treatment with

an antiparkinson medication by 2.27- and 1.50-fold in men and women,

respectively. The corresponding rate ratios with lithium were 2.22 and 1.64.

The new findings support other recent reports suggesting an association

between affective/anxiety disorders and Parkinson's disease. It is

possible that the treatments for these disorders, and not the disorders

themselves, are what precipitate Parkinson's disease, the authors point out.

J Neurol Neurosurg Psychiatry 2006;77:781-783.

--

ne Holden, MS, RD < fivestar@... >

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/

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