Feverfew May Reduce the Frequency of Migraine Headaches

[Guest guest]

Colleagues, the following is FYI and does not necessarily reflect my own

opinion. I have no further knowledge of the topic. If you do not wish to

receive these posts, set your email filter to filter out any messages

coming from @nutritionucanlivewith.com and the program will remove

anything coming from me.

---------------------------------------------------------

Feverfew May Reduce the Frequency of Migraine Headaches

Reference: “Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract

(MIG-99) in migraine prevention--a randomized, double-blind,

multicentre, placebo-controlled study,” Diener HC, Pfaffenrath V, et al,

Cephalalgia, 2005; 25(11): 1031-41. (Address: Neurologische

Universitatsklinik, Essen, Germany. E-mail: h.diener@... ).

Summary: In a randomized, double-blind, placebo-controlled,

multi-center, parallel-group study involving 170 patients who experience

migraine headaches, treatment with a CO(2)-extract of the herb,

feverfew, was found to significantly reduce the frequency of migraine

headache episodes over a period of 16 weeks. Subjects were randomly

divided into two groups. After a four week baseline period, one group of

subjects (n=89) was given CO(2)-extract of feverfew (MIG-99) at a dose

of 6.25 mg, three times a day, while the other group of subjects was

given a placebo. The average number of migraine headache episodes per 28

days was recorded during the baseline and treatment periods. Results

found that subjects in the MIG-99 group experienced a more significant

decrease in the frequency of migraine headaches per 28 days, as compared

to subjects in the placebo group. An odds ratio of 3.4 in favor of

MIG-99 was determined through logistic regression of responder rates. In

terms of tolerabili ty, adverse events that possibly related to the

study were reported in 10.2% of subjects taking the placebo and 8.4% of

subjects taking MIG-99. These results suggest that persons with migraine

headaches may benefit from daily treatment with a CO(2)-extract of feverfew.

--

ne Holden, MS, RD < fivestar@... >

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/