Live webcast of this workshop will be available on January 22-23

[Guest guest]

WORKSHOP OVERVIEW

Live webcast of this workshop will be available on January 22-23,

2007

http://www-apps.niehs.nih.gov/conferences/od/cehr/

Download the Workshop Factsheet

(PDF 651K)The goal of this workshop is to develop new strategies for

research, exposure and effects monitoring, intervention and

prevention in children's environmental health. Specific objectives

are to maximize the effectiveness of scientific research - basic

science, exposure monitoring/biomonitoring, epidemiology,

toxicology, clinical medicine and multidisciplinary studies - and to

enhance the translation of research to the bedside, to the community

and to public policy. The first day will begin with discussions of

two case studies that demonstrate the successful implementation of

evidence-based intervention/prevention strategies that became

possible once links between environmental exposures and a disease in

children had been identified. The first case study will focus on

lead and neurotoxicity. Findings on the adverse effects of lead on

neurodevelopment ultimately led to efforts to reduce exposures to

lead. Asthma will be used as a second case study because it provides

a clear example of environmental triggers and some science-based

prevention/intervention strategies that are already being

implemented. The second day of the workshop will focus on applying

lessons learned from the two " success " case studies to two

children's disorders that appear to have environmental etiologies

but are less well understood: disorders of lipid and carbohydrate

metabolism and attention deficit/hyperactivity disorder (ADHD).

A discussion will follow each case study presentation to consider

the opportunities, the barriers and the design challenges that

confront future clinical, toxicological, epidemiological, exposure

monitoring, and basic research in children's environmental health.

Specific topics include:

Past approaches to research translation to see what worked and what

failed to work.

The critical mass of researchers and mix of disciplines needed to

most efficiently advance research in children's environmental

health.

Biomarkers of exposure, susceptibility, or subclinical dysfunction.

The use of " omics " technologies that might be incorporated into

future toxicological, epidemiological and/or biomonitoring studies

to enhance their sensitivity and efficiency.

Is there a point at which the use of new scientific tools might slow

the pace of progress?

New approaches to accelerating the translation of science to

treatment, prevention, and the remediation of environmental risks to

children's health.

Potential study populations at uniquely high risk of disease.

Data resources - records, disease registries, well-characterized

cohort populations, tissue banks, or stored DNA - in the U.S. or

abroad that might facilitate future studies.

New partnerships in research.

This meeting is open to the public with time set aside for public

discussion. For additional information, contact Dr. a Thayer

(thayer@... or 919-541-5021).

Contact Us Last Modified: 8 November 2006

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