Trial of isolation of sick house syndrome and unclassified multiple chemical sensitivities--Definition of sick house syndrome, and symptoms

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1: Arerugi. 2006 Dec;55(12):1515-30. Links

[Trial of isolation of sick house syndrome and unclassified multiple chemical

sensitivities--Definition of sick house syndrome, and symptoms]

[Article in Japanese]

a.. Torii S,

b.. Hirayama K,

c.. Akiyama K,

d.. Ikezawa Z,

e.. Uchio E,

f.. Okamoto Y,

g.. Ogura H,

h.. Takahashi K,

i.. Nishima S.

Department of Home Economics, Aichi Gakusen University. shinpei@...

PURPOSE: This study was designed to clarify the definition of sick house

syndrome (SHS). METHODS: SHS was defined based on the disease related to

habitation as follows. 1. The cause of the onset of a disease relates to house.

2. Symptoms appear within house. 3. Symptoms will be less serious or disappear

if patient away from house. 4. If patient goes into house, symptoms will appear

repeatedly. When it corresponded to all above, it was defined to SHS, and it

classified as MCS (multiple chemical sensitivities) without above conditions.

Even if SHS is isolated from similar disease completely, characteristic symptoms

of MCS are hard to be detected because MCS are combination of two or more

diseases. Based on this working hypothesis, the logistic regression by setting

MCS as reference was performed so that characteristic symptoms of SHS show odds

ratios with exceeding one. RESULTS: The odds ratios with more than two of

characteristic symptoms in SHS were " nausea or vomiting " " Troublesome in

everything " and the causative substances to which symptoms get worse was " The

smell of a perfume and cosmetics " . Characteristic symptoms of an allergy disease

were detected by comparison with the allergic conjunctivitis, allergic rhinitis,

and bronchial asthma, respectively. CONCLUSION: These results showed that the

classification method was appropriate. This definition is not fundamentally

differed from the definition of the sick-building syndrome of WHO.

PMID: 17185912 [PubMed - indexed for MEDLINE]

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