*Another* reason for the variabilities in suceptibility to inflammation.

[Guest guest]

I was recently surfing Medline and I stumbled across a paper giving

yet another reason for variabilities in suceptibility to inflammatory

stimuli, dietary n-3 PUFA status at birth, and prematurity.

In other words, babies born prematurely who don't get enough n-3 fatty

acids (like fish oil, flaxseed oil, or DHA in their mothers milk- say

they were fed formula, which doesnt contain DHA, instead) when their

brains are growing - have a higher chance of being more suceptible to

inflammation later in life.

There are lots MORE reasons besides that (besides the HLA-DR genetics)

why many people might be more suceptible to mold illness causing

permanent damage to their systems.. Here are just a few of them.

1.) Age - the older you are the more inflammation there is already in

your body due to

glycation of your bodys connective tissue. So the more likely you are

to see damage from damp building toxins. But also the older you are

the less of a chance of there being a fever to show this. The body is

so used to inflammation at that point, it doesnt get a fever.

2.) LPS - lipopolysaccarides - endotoxins in your body or in your

environment that get into your body, somehow, for example, damp

buildings, in addition to mold, often also harbor high levels of

endotoxin-laden bacteria. They get breathed in just like mold gets

breathed in. Or, someone might have reflux or some other condition

that results in endotoxins from their gut getting into their

bloodstream. This dramatically potentiates trichothecene mycotoxins.

3.) Nutrition - Many, many nutritive factors seem to effect

suceptibility to inflammation from mold toxins, and similar other

toxins, and the probability is also very high that a bout with mold

illness will also effect, maybe permanently, your ability to absorb

nutrients.. for example, the ability of your body to synthesize some

nutrients from others.. for example, to turn some amino acids into

others, a process which is essential for a number of biological

processes to happen. This derangement, because it occurs over such a

long period of time, seems to me to be impossible to simulate in a

laboratory.

4.) Physiological factors due to stress and lack of sleep, preventing

the body's repair processes from occuring and also preventing the

manufacture of neuroprotective endogenous hormones like melatonin and

many peptides and nerve growth factors that in addition to helping

nerves grow - the process of consolidating information learned during

each day, for example, they also protect the nervous system from

damage due to neurotoxicants.

Get the picture? The point I am trying to make is that scientists need

to look at the big picture, instead of trying to isolate each

occurance they need to look at all of them in the more likely

environment of the body's processes -and *its* environment.