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http://home.businesswire.com/portal/site/google/index.jspndmViewId=news_view & n

ewsId=20070430005955 & newsLang=en

NCCN Updates Prevention and Treatment of Cancer-Related Infections

Guidelines

The new name and expanded focus come in response to the complexity of

immunocompromised conditions in patients with cancer and the spectrum of

pathogens

to which they are susceptible. New prevention and treatment recommendations

have been added for other highly immunocompromised patients with cancer such

as allogeneic hematoptoietic stem cell transplant recipients, patients with or

at risk for graft-versus-host disease, and patients receiving high-dose

corticosteroids, purine analogues and alemtuzumab.

.... In addition, the availability of newer broad spectrum antifungal agents

with a good safety profile raise the possibility of using mold-active

prophylaxis in patients at high risk for invasive fungal infections without the

need

to empirically modify antifungal therapy solely on persistent neutropenic

fever of unknown etiology. Algorithms that include chest CT scans and laboratory

surrogates for invasive fungal infections are also discussed in the updated

guidelines.

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