OT: NIOSH Alert on Hazardous Drugs Process for updating the list of hazardous drugs

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Process for updating the list of hazardous drugs Draft

Document for Public Review and Comment:

Process for updating the list of hazardous drugs (Appendix A) for the NIOSH

Alert on Hazardous Drugs

NIOSH Docket #105

http://www.cdc.gov/niosh/review/public/105/default.html

The National Institute for Occupational Safety and Health is requesting public

comment on the definition of hazardous drugs and adding new drugs to the

existing list of hazardous drugs in the workplace.

The NIOSH Alert: Preventing Occupational Exposures to Antineoplastic and Other

Hazardous Drugs in Health Care Settings was published in September 2004

(http://www.cdc.gov/niosh/docs/2004-165/). Since that time, approximately 70

new drugs have received FDA approval and approximately 60 drugs have received

special warnings (usually black box warnings) based on reported adverse effects

in patients. An additional 18 drugs were included from the updated NIH

Hazardous Drug List. From this list of approximately 150 drugs, 62 drugs were

determined to have one or more characteristic of a hazardous drug.

NIOSH has assessed the scientific literature and found no reason to change the

definition of hazardous drugs at this time. NIOSH has also evaluated the

information available for the three groups of drugs and identified a subset of

62 drugs that may be hazardous to health care workers who handle them.

This preliminary list represents drugs that fit one or more of the

characteristics of a hazardous drug as defined by NIOSH.

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