Treatment of two postoperative endophthalmitis cases due to Aspergillus flavus and Scopulariopsis spp

[Guest guest]

Treatment of two postoperative endophthalmitis cases due to Aspergillus flavus

and Scopulariopsis spp. with local and systemic antifungal therapy

Sayime Aydin , Bulent Ertugrul , Berna Gultekin , Guliz Uyar and Erkin Kir

BMC Infectious Diseases 2007, 7:87 doi:10.1186/1471-2334-7-87

Published 31 July 2007

http://www.biomedcentral.com/1471-2334/7/87

Abstract (provisional)

The complete article is available as a provisional PDF.

http://www.biomedcentral.com/content/pdf/1471-2334-7-87.pdf

The fully formatted PDF and HTML versions are in production.

Background

Endophthalmitis is the inflammatory response to invasion of the eye with

bacteria or fungi. The incidence of endophthalmitis after cataract surgery

varies between 0.072-0.13 %. Treatment of endophthalmitis with fungal etiology

is difficult.

Case presentation

Case 1: A 71-year old male diabetic patient developed postoperative

endophthalmitis due to Aspergillus flavus. The patient was treated with topical

amphotericin B ophthalmic solution, intravenous (IV) liposomal amphotericin-B

and caspofungin following vitrectomy. Case 2: A 72-year old male cachectic

patient developed postoperative endophthalmitis due to Scopulariopsis spp. The

patient was treated with topical and IV voriconazol and caspofungin.

Conclusions

Aspergillus spp. are responsible of postoperative fungal endophthalmitis.

Endophthalmitis caused by Scopulariopsis spp. is a very rare condition. The two

cases were successfully treated with local and systemic antifungal therapy.

---------------------------------

Choose the right car based on your needs. Check out Autos new Car Finder

tool.