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Another list of references...

worth saving to print up and give to doctors, etc. Or maybe putting in

the files section?

Has this been posted here before?

EPA

1. Mudarri D, Fisk WJ. Public health and economic impact of dampness and

mold. Indoor Air 2007; 17: 226-236.

Causality

1. Hill AB. The environment and disease: association or causation?

Proceedings of Royal Society of Medicine Section of Occupational Medicine

01/14/65; 295-230.

2. Kundi M. Causality and the interpretation of epidemiologic evidence

Environmental Health Perspectives 2006; 114(7): 969-974.

3. CV, Goodman KJ. The missed lessons of Sir Austin Bradford Hill.

Epidemiologic Perspectives and Innovations 2004; 1(3): 1-5.

4. Carbone M, Klein G, Gruber J, Wong M. Modern criteria to establish human

cancer etiology. Cancer Research 2004; 64: 5518-5524.

5. Altman DG, Bland JM. Absence of evidence is not evidence of absence. BMJ

1995; 311: 485.

6. Maldonado G, Greenland S. Estimating causal effects. International

Journal of Epidemiology 2002; 31: 422-429.

7. Broderick G, Craddock RC, Whistler T, R, Klimas N, Unger ER.

Identifying illness parameters in fatiguing syndromes using classical

projection methods. Pharmacogenomics 2006; 7(3): 407-419.

VCS

1. Frederick R, Furtaw Jr EJ, Haugland RA, Hudnell K, Kolb L, Menetrez MY,

Macler B, Selgrade MK, Shoemaker JA, Van Emon JM, Vesper SJ, Ward MW, Wymer

LJ. Exposure of children to indoor molds. EPA Science Forum 2004;

http://cfpub2.epa.gov/ordpubs/nerlpubs/nerlpubs_mcear_2004.cfm?ActType=Pu

CDC/New Orleans

1. Redd SC. State of the science on molds and human health. 2002; 1-10.

2. Rao CY, Riggs MA, Chew GL, Muilenburg ML, Thorne PS, Van Sickle D, Dunn

KH, Brown C. Characterization of airborne molds, endotoxins, and glucans in

homes in New Orleans after Hurricanes Katrina and Rita. Applied and

Environmental Microbiology 2007; 73(5): 1630-1634.

3. Verhoeff AP, Burge HA. Health risk assessment of fungi in home

environments. Ann Allergy Asthma Immunol 1997; 78: 544-556.

4. Gent JF, Ren P, Belanger K, Triche E, Bracken MB, Holford TR, Leaderer

BP. Levels of household mold associated with respiratory symptoms in the

first year of life in a cohort at risk for asthma. Environmental Health

Perspectives 2002; 110(12): A781-A786.

5. GM, Hjelmroos-Koski M, Rotkin-Ellman M, Hammond SK. Airborne mold

and endotoxin concentrations in New Orleans, Louisiana, after flooding,

October through November 2005. Environmental Health Perspectives 2006;

114(9): 1381-1386.

6. Chew GL, J, Rabito FA, Grimsley F, Iqbal S, Reponen T, Muilenberg

ML, Thorne PS, Dearborn DG, Morley RL. Mold and endotoxin levels in the

aftermath of Hurricane Katrina: a pilot project of homes in New Orleans

undergoing renovation. Environmental Health Perspectives 2006; 114(2): 1883-

1889.

7. Brandt M, Burkhart J, Burton NC, -Ganser J, Damon S, Falk H, Fridkin

S, Garbe P, Kreiss K, McGeehin M, J, Page E, Rao C, Redd S, Sinks T,

Trout D, Wallingford KM, Warnock D, Weissman DN. Mold Prevention strategies

and possible health effects in the aftermath of Hurricanes Katrina and Rita.

CDC October 2005; 1-45.

Canada Ministry of Health

1. Minister of Health. Residential indoor air quality guideline for moulds.

2007-03-31 Canada Gazette Part I, 141(13).

ERMI

1. Vesper SJ, McKinstry C, Haugland RA, Iossofova Y, Lemasters G, Levin L,

Hersgey GKK, Villareal M, Bernstein DI, Lockey J, Reponen T. Relative

moldiness index as predictor of childhood respiratory illness. Journal of

Exposure Science and Environmental Epidemiology 2006; 1-7.

2. Vesper S. Developing the EPA relative moldiness index based on

mold-specific quantitative PCR. The Synergist 2006; 39-43.

3. Vesper SJ, McKinstry C, Yang C, Haugland RA, Kercsmar CM, Yike I,

Schluchter MD, Kirchner HL, Sobolewski J, Allan TM, Dearborn DG. Specific

molds associated with asthma in water-damaged homes. JOEM 2006; 48(8): 852-

858.

Association Studies

1. Hodgson MJ, Morey P, Leung WY, Morrow L, D, Jarvis BB, Robins H,

Halsey JF, Storey. Building-associated pulmonary disease from exposure to

Stachybotrys chartarum and Aspergillus versicolor. J Occup Environ Med 1998;

40(3): 241-249.

2. Reijula K, Tuomi T. Mycotoxins of aspergilli: exposure and health

effects. Front Biosci 2003; 8: s232-235.

3. Skaug MA, Eduard W, Stormer FC. Ochratoxin A in airborne dust and fungal

conidia. Mycopathologia 2001; 151(2): 93-98.

4. Sebastian A, Larsson L. Characterization of the microbial community in

indoor environments: a chemical-analytical approach. Appl Envir Microbiol

2003; 69: 3103-3109.

5. Horner WE, Worthan AG, Morey PR. Air- and dust mycoflora in houses free

of water damage and fungal growth. Appl Environ Microbiol 2004; 70:

6394-6400.

6. Murtoniemi T, Nevalainen A, Suutari M, Toivola M, Komulainen H, Hirvonen

MR. Induction of cytotoxicity and production of inflammatory mediators in

raw 264.7 macrophages by spores grown on six different plasterboards. Inhal

Toxicol 2001; 13(3): 233-247.

7. Bloom E, Bal K, Nyman E, Must A, Larsson L. Mass spectrometry-based

strategy for direct detection and quantification of some mycotoxins produced

by Stachybotrys and Aspergillus spp. in indoor environments. Applied and

Environmental Microbiology 2007; 73(13): 4211-4217.

8. Boutin-Forzano S, Charpin-Kadouch C, Chabbi S, Bennedjai N, Dumon H,

Charpin D. Wall relative humidity: a simple and reliable index for

predicting Stachybotrys chartarum infestation in dwellings. Indoor Air 2004;

14(3): 196-199.

9. Menzies D, Comtois P, Pasztor J, Nunes F, Hanley JA. Aeroallergens and

work- related respiratory symptoms among office workers. J Allergy Clin

Immunol 1998; 101(1): 38-44.

10. Meyer HW, Wurtz H, Suadicani P, Valbjern O, Sigsgaard T, Gyntelberg F.

Molds in floor dust and building-related symptoms among adolescent school

children: a problem for boys only? Indoor Air 2005; 15(Suppl 10): 17-24.

11. Bornehag G, Sundell J, Sigsgaard T. Dampness in buildings and health

(DBH): report from an ongoing epidemiological investigation on the

association between indoor environmental factors and health effects among

children in Sweden. Indoor Air 2004; 14(Suppl 7): 59-66.

12. Park JH, -Ganser J, Rao C, Kreiss K. Fungal and endotoxin

measurements in dust associated with respiratory symptoms in a water-damaged

office building. Indoor Air 2006; 16: 192-203.

13. Andersson MA, Nikulin M, Koljajg U, Andersson MC, Rainey F, Reijula K,

Hintikka EL, Salkinojia-Salonen M. Bacteria, molds, and toxins in

waterdamaged building materials. Applied and Environmental Microbiology

1997; 63(2): 387-393.

14. Dales RE, Burnett R, Zwanenburg H. Adverse health effects among adults

exposed to home dampness and molds. Am Rev Respir Dis 1991; 143: 505-509.

15. Petola J, Andersson MA, Haahtela T, Mussalo-Rauhamaa H, Rainey FA,

Kroppenstedt RM, Samsom RA, Salkinoja-Salonen MS. Toxic-metabolite producing

bacteria and fungus in an indoor environment. Applied and Environmental

Microbiology 2001; 67(7): 3269-3274.

16. Page EH, Trout DB. The role of Stachybotrys mycotoxins in

building-related illness. AIHAJ 2001; 62: 644-648.

17. Wan GH, Li CS. Dampness and airway inflammation and systemic symptoms in

office building workers. Archives of Environmental Health 1999; 54(1):

58-63.

18. Mahooti- N, Storey E, Yang C, Simcox NJ, W, Hodgson M.

Characterization of mold and moisture indicators in the home. Journal of

Occupational and Environmental Hygiene 2004; 1: 826-839.

19. -Ganser JM, White SK, R, Hilsbos K, Storey E, Enright PL, Rao

CY, Kreiss K. Respiratory morbidity in office workers in a water-damaged

building. Environmental Health Perspectives 2005; 113(4): 485-490.

20. Gunnbjornsdottir MI, lin KA, Norback D, Bjornsson E, Gisason D,

Lindberg E, Svanes C, Omenaas E, Norrman E, Jogi R, Jensen EJ, Dahlman-

Hoglund A, Janson C. Prevalence and incidence of respiratory symptoms in

relation to indoor dampness: the RHINE study. Thorax 2006; 61: 221-225.

21. B, Ritz B, Gehring U, Koch A, Bischof W, Wichmann HE, Heinrich J.

Indoor exposure to molds and allergic sensitization. Environmental Health

Perspectives 2002; 110(7): 647-653.

22. Gunnbjornsdottir MI, Norback D, Plaschke P, Norrman E, Bjornsson E,

Janson C. The relationship between indicators of building dampness and

respiratory health in young Swedish adults. Respir Med 2003; 94(4): 302-307.

23. AD, Woodruff TJ, Axelrad DA. Integrated assessment of environment

and health: America's children and the environment. Environmental Health

Perspectives 2006; 114(4): 447-452.

24. Weschler CJ, Wells JR, Poppendieck D, Hubbard H, Pearce TA. Workgroup

report: indoor chemistry and health. Environmental Health Perspectives 2006;

114(3): 442-504.

25. JD, Rand TG, Jarvis BB. Stachybotrys chartarum: cause of human

disease or media darling? Medical Mycology 2003; 41: 271-291.

26. Jaakkola MS, Nordman H, Piipari R, Uitti J, Laitinen J, Karjalainen A,

Hahtola P, Jaakkola JJK. Indoor dampness and molds and development of

adult-onset asthma: a population-based incident case-control study.

Environmental Health Perspectives 2002; 110(5): 543-547.

27. Gent JF, Ren P, Belanger K, Triche E, Bracken MB, Holford TR, Leaderer

BP. Levels of household mold associated with respiratory symptoms in the

first year of life in a cohort at risk for asthma. Environmental Health

Perspectives 2002; 110(12); A781-A792.

28. Apostolakos MJ, Rossmoore H, Beckett WS. Hypersensitivity pneumonitis

from ordinary residential exposures. Environmental Health Perspectives 2001;

109(9): 979-981.

29. Trout D, Bernstein J, ez K, Biagini R, Wallingford K. Bioaerosol

lung damage in a worker with repeated exposure to fungi in a water-damaged

building. Environmental Health Perspectives 2001; 109(6): 641-644.

30. Menetrez MY. Emission exposure model for the transport of toxic mold.

Indoor and Built Environment 2004; 13(1); 75-82.

31. Craner J. Building-related illness in occupants of mold-contaminated

houses: a case series. Eastern New York Occupational & Environmental Health

Center 1999; 146-157.

32. Engelhart S, Loock A, Skutlarek D, Sagunski H, Lommel A, Farber H, Exner

M. Occurrence of toxigenic Aspergillus versicolor isolates and

sterigmatocystin in carpet dust from damp indoor environments. Applied and

Environmental Microbiology 2002; 68(8): 3886-3890.

33. Murtoniemi T, Nevalainen A, Hirvonen MR. Effect of plasterboard

composition on Stachybotrys chartarum growth and biological activity of

spores. Applied and Environmental Microbiology 2003; 69(7): 3751-3757.

34. Shelton BG, Kirkland KH, Flanders WD, GK. Profiles of airborne

fungi in buildings and outdoor environments in the United States. Applied

and Environmental Microbiology 2002; 68(4): 1743-1753.

35. Sebastian A, Larson L. Characterization of the microbial community in

indoor environments: a chemical-analytical approach. Applied and

Environmental Microbiology 2003; 69(6): 3103-3109.

36. Hormer WE, Worthan AG, Morey PR. Air and dustborne mycoflora in houses

of water damage and fungal growth. Applied and Environmental Microbiology

2004; 70(11): 6394-6400.

37. Burge HA. Health effects of biological contaminants. Indoor Air and

Human Health Chapter 10 CRC Press 1996; 171-178.

38. ez KF, Rao CY, Burton NC. Exposure assessment and analysis for

biological agents. Grana 2004; 43: 193-208.

39. Pessi AM, Suonketo J, Pentti M, Kurkilahti M, Peltola K,

Rantio-Lehtimaki A. Microbial growth inside insulated external walls as an

indoor air biocontamination source. Applied and Environmental Microbiology

2002; 68(2): 963-967.

40. Krauter P, Biermann A. Reaerosolization of fluidized spores in

ventilation systems. Applied and Environmental Microbiology 2007; 73(7):

2165-2172.

41. Thrasher JD, Kilburn K, Immes N. Indoor environment resulting from water

intrusion. Perspectives 2006; 4-53.

42. Flannigan B, McCabe EM, McGarry F. Allergenic and toxigenic

micro-organisms in houses. Journal of Applied Bacteriology Symposium

Supplement 1991; 70: 61S-73S.

43. Verhoeff AP, van Strien RT, van Wijnen JH, Brunekreef B. Damp housing

and childhood respiratory symptoms: the role of sensitization to dust mites

and molds. American Journal of Epidemiology 1995; 141(2): 103-109.

44. Malloy CD, Marr JS. Mycotoxins and public health: a review. J Public

Health Management Practice 1997; 3(3): 61-69.

45. Smoragiewucz W, Cossette B, Boutard A, Krzystyniak K. Trichothecene

mycotoxins in the dust of ventilation systems in office buildings. Int Arch

Occup Environ Health 1993; 65: 113-117.

46. Johanning E, Biagini R, Hull D, Morey P, Jarvis B, Landsbergis P. Health

and immunology study following exposure to toxigenic fungi (Stachybotrys

chartarum) in a water-damaged office environment. Int Arch Occup Environ

Health 1996; 68: 207-218.

47. Croft WA, Jarvis BB, Yatawara CS. Airborne outbreak of trichothecene

toxicosis. Atmospheric Environment 1986; 20(3): 549-552.

48. Hodgson MJ, Morey P, Leung WY, Morrow L, D, Jarvis BB, Robbins H,

Halsey JF, Storey E. Building-associated pulmonary disease from exposure to

Stachybotrys chartarum and Aspergillus versicolor. JOEM 1998; 40(3):

242-249.

49. Johanning E, Landsbergis P, Gareis M, Yang CS, Olmsted E. Clinical

experience and results of a sentinel health investigation related to indoor

fungal exposure. Environmental Health Perspectives 1999; 107(3): 489-494.

50. Sorenson WG. Fungal spores: hazardous to health? Environmental Health

Perspectives 1999; 107(3): 469-472.

51. Rautiala S, Reponen T, Hyvarinen A, Nevalainen A, Vehvilainen A,

Kalliokoski P. Exposure to airborne microbes during the repair of moldy

buildings. American Industrial Hygience Asso Journal 1996; 57: 279-284.

52. Tuomi T, Reijula K, sson T, Hemminki K, Hintikka EL, Lindroos O,

Kalso S, Koukila-Kahkola P, Mussalo-Rauhamaa H, Haajtela T. Mycotoxins in

crude building materials from water-damaged buildings. Applied and

Environmental Microbiology 2000; 66(5): 1899-1904.

53. Redlich CA, Sparer J, Cullen MR. Sick-building syndrome. Lancet 1997;

349: 1013-1015.

Mycotoxin Effects

1. Meloche JL, TK. Altered tissue amino acid metabolism in acute T-2

toxicosis. Proc Soc Exp Biol Med 1995; 210(3): 260-265.

2. Smoragiewicz W, Cossette B, Boutard A, Krzystyniak K. Trichothecene

mycotoxins in the dust of ventilation systems in office buildings. Int Arch

Occup Environ Health 1993; 65(2): 113-117.

3. Charpin-Kadouch C, Maurel G, Felipo R, Queralt J, Ramadour M, Henri D,

Garans M, Botta A, Charpin D. Mycotoxin identification in moldy dwellings.

Journal of Applied Toxicology 2006; 26: 475-479.

4. Yike I, Distler Am, Ziady AG, Dearborn DG. Mycotoxin adducts on human

serum albumin: biomarkers of exposure to Stachybotrys chartarum.

Environmental Health Perspectives 2006; 114(8): 1221-1226.

5. Nieminen SM, Karki R, Auriola S, Toivola M, Laatsch H, Laatikainen R,

Hyvarinen A, von A. Isolation and identification of Aspergillus

fumigatus mycotoxins on growth medium and some building materials. Applied

and Environmental Microbiology 2002; 68(10): 4871-4875.

6. Brasel TL, AW, Demers RE, Ferguson BS, Fink J, Vojdani A,

SC, Straus DC. Detection of trichothecene mycotoxins in sera from

individuals exposed to Stachybotrys chartarum in indoor environments.

Archives of Environmental Health 2004; 59(6): 317-323.

7. Brasel TL, JM, Carriker CG, SC, Straus DC. Detection of

airborne Stachybotrys chartarum macrocyclic trichothecene mycotoxins in the

indoor environment. Applied and Environmental Microbiology 2005; 71(11):

7376- 7388.

8. Panaccione DG, Coyle CM. Abundant respirable ergot alkaloids from the

common airborne fungus Aspergillus fumigatus. Applied and Environmental

Microbiology 2005; 71(6): 3106-3111.

9. JW, Klich M. Mycotoxins. Clin Microbiol Rev 2003; 16(3): 497-516.

10. Rao CY, Brain JD Burge HA. Reduction of pulmonary toxicity of

Stachybotrys chartarum spores by methanol extraction of mycotoxins. Applied

and Environmental Microbiology 2000; 66(7): 2817-2821.

11. Wannemacher RW, Wiener SL. Trichothecene Mycotoxins. Textbook of

Military Medicine: Medical Aspects of Chemical and Biological Warfare:

Chapter 34.

12. Creasia DA, Thurman JD, J, Nealley ML, York CG, Wannemacher RW,

Bunner DL. Acute inhalation toxicity of T-2 mycotoxin in mice. Fundamental

and Applied Toxicology 1987: 8: 230-235.

13. Karunasena E, Cooley JD, DR, Straus DC. Protein translation

inhibition by Stachybotrys chartarum conidia with and without the mycotoxins

containing polysaccharide matrix. Mycopathologia 2004; 158: 87-97.

14. Peltola J, Ritieni A, Mikkola R, Grigoriev PA, Pocafalvi G, Andersson

MA, Salkinoja-Salonen MS. Biological effects of Trichoderma harzianum

peptaibols on mammalian cells. Applied and Environmental Microbiology 2004;

70(8): 4996-5004.

15. Neville J, Hodgson M. Background and toxicity on some mycotoxins commonly

found in water damaged buildings and outside ambient environment. PK-Jarvis

Microbiological, LLC.

16. Sorenson WG, Frazer DG, Jarvis BB, Simpson J, VA. Trichothecene

mycotoxins in aerosolized conidia of Stachybotrys atra. Applied and

Environmental Microbiology 1987; 53(6): 1370-1375.

17. Etzel RA. Mycotoxins. JAMA 2002; 287(4): 425-428.

18. Jarvis BB, Salemme J, Morais A. Stachybotrys toxins. 1 Natural

Toxins 1995; 3:

10-16.

19. Yike I, Rand TG, Dearborn DG. Acute inflammatory responses to Stachybotrys

chartarum in the lungs of infant rats: time course and possible mechanisms.

Toxicol Sci 2005; 84(2): 407-417.

20. Rand TG, Flemming J, J, Womiloju TO. Comparison of

inflammatory responses in mouse lungs exposed to atranones A and C from

Stachybotrys chartarum. J Toxicol Environ Health A 2006; 69(13): 1239-1251.

21. Rosenblum Lichtenstein JH, Molina RM, Donaghey TC, Brain JD. Strain

differences influence murine pulmonary responses to Stachybotrys chartarum.

Am J Respir Cell Mol Biol 2006; 35(4): 415-423.

22. Sorenson WG, Frazer DG, Jarvis BB, Simpson J, VA. Trichothecene

mycotoxins in aerosolized conidia of Stachybotrys atra. Appl Environ Microbiol

1987; 53(6): 1370-1375.

23. Tuomi T, Reijula K, sson T, Hemminki K, Hintilla EL, Lindroos

O, Kalso S,

Koukila-Kahkola P, Mussalo-Rauhamaa H, Haahtela T. Mycotoxins in crude

building materials from water-damaged buildings. Appl Environ Microbiol 2000;

66(5): 1899-1904.

24. Nielsen KF, Gravesen S, Nielsen PA, Andersen B, Thrane U, Frisvad JC.

Production of mycotoxins on artificially and naturally infested

building materials.

Mycopathologia 1999; 145(1): 43-56.

25. Hodgson MJ, Morey P, Leung WY, Morrow L, D, Jarvis BB, Robbins H,

Halsey JF, Storey E. Building-associated pulmonary disease from exposure to

Stachybotrys chartarum and Aspergillus versicolor. J Occup Environ Med 1998;

40(3): 241-249.

26. Jarvis BB, JD. Mycotoxins as harmful indoor air contaminants. Appl

Microbiol Biotechnol 2005; 66(4): 367-372.

27. Fog Nielsen K. Mycotoxin production by indoor molds. Fungal Genet Biol 2003;

39(2): 103-117.

28. Fiedler K, Schutz E, Geh S. Detection of microbial volatile

organic compounds

(MVOCs) produced by moulds on various materials. Int J Hyg Environ Health

2001; 204(2-3): 111-121.

29. Gao P, J. Volatile metabolites produced by three strains of

Stachybotrys

chartarum cultivated on rice and gypsum board. Appl Occup Environ Hyg 2002;

17(6): 430-436.

Nay Sayers

1. Lees-Haley PR. Toxic mold and mycotoxins in neurotoxicity cases:

Stachybotrys,

Fusarium, Trichoderma, Aspergillus, Penicillium, Cladosporium, Alternaria,

Trichothecenes. Psychol Rep 2003; 93(2): 561-584.

2. Zacharisen MC, Fink JN. Is indoor " mold madness " upon us? ls of Allergy,

Asthma & Immunology 2005; 94: 12-13.

3. Marmot AF, Eley J, Stafford M, Stansfeld SA, Warwick E, Marmot MG. Building

health: an epidemiological study of " Sick building syndrome " in the Whitehall II

study. Occup Environ Med 2006; 63: 283-289.

4. Khalili B, Montanaro MT, Bardana EJ. Indoor mold and your patient's health:

from suspicion to confirmation. The Journal of Respiratory Diseases 2005;

26(12): 520-526.

5. Bobbitt RC, Crandall MS, Venkataraman A, Bernstein JA. Characterization of a

population presenting with suspected mold-related health effects. Ann Allergy

Asthma Immunol 2005; 94: 39-44.

6. Robbins CA, Swenson LJ, Nealley ML, Gots RF, Kelman BJ. Health effects of

mycotoxins in indoor air: a critical review. Applied Occupational and

Environmental Hygiene 2000; 15(10): 773-784.

7. Kelman BJ, Robbins CA, Swenson LJ, Hardin BD. Risk from inhaled mycotoxins

in indoor office and residential environments. International Journal

of Toxicology

2004; 23: 3-10.

8. Council on Scientific Affairs. Adverse human health effects associated with

molds in the indoor environment. JOEM 2003; 45(5): 470-478.

9. Sudakin DL. Toxigenic fungi in a water-damaged building: an

intervention study.

American Journal of Industrial Medicine 1998; 34: 183-190.

10. Sudakin DL. Stachybotrys chartarum: current knowledge of its role

in disease.

Medscape General Medicine 2000; 1-8.

11. Hossain MA, Ahmed MS, Ghannoum MA. Attributes of Stachybotrys chartarum

and its association with human disease. J Allergy Clin Immunol 2004; 113(2):

200-208.

12. Kuhn DM, Ghannoum MA. Indoor mold, toxigenic fungi, and Stachybotrys

chartarum: infectious disease perspective. Clinical Microbiology Reviews 2003;

16(1): 144-172.

13. Terr AI. Stachybotrys: relevance to human disease. Ann Allergy Asthma

Immunol 2001; 87(Suppl): 57-63.

14. Kolstad HA, Brauer C, Iversen M, Sigsgaard T, Mikkelsen S. Do

indoor molds in

nonindustrial environments threaten workers' health? A review of the

epidemiologic evidence. Epidemiol Rev 2002; 24: 203-217.

15. Fung F, Hughson WG. Health effects of indoor fungal Bioaerosol exposure.

Applied Occupational and Environmental Hygiene 2003; 18: 535-544.

16. Mahmoudi M, Gershwin ME. Sick building syndrome. III. Stachybotrys

chartarum. Journal of Asthma 2000; 37(2): 191-198.

Biowarfare

1. Casadevall A, Pirofski LA. The weapon potential of human pathogenic fungi.

Medical Mycology 2006; 44: 689-696.

2. Sidell FR, Takafuji ET, Franz DR. Medical aspects of chemical and biological

warfare. 1997; NLM Unique ID: 9709389.

Hormonal Effects

1. MJ, Smart RA, Sharma RP. Relationship of the

hypothalamic-pituitaryadrenal

axis with chemically induced immunomodulation. I. Stress-like response

after exposure to T-2 toxin. Toxicology 1989; 56(2): 179-195.

2. Desruisseaux MS, Nagajyothi, Trujillo ME, Tanowitz HB, Scherer PE.

Adipocyte, adipose tissue, and infectious disease. Infection and Immunity 2007;

75(3): 1066-1078.

3. -Rey E, Chorny A, Delgado M. Regulation of immune tolerance

by antiinflammatory

neuropeptides. Nature Reviews Immunology 2007; 7: 52-63.

Fragments

1. Cho SH, Seo SC, Schmechel D, Grinshpun SA, Reponen T. Aerodynamic

characteristics and respiratory deposition of fungal fragments. Atmospheric

Environment 2005; 39: 5454-5465.

2. Brasel TL, DR, SC, Straus DC. Detection of airborne

Stachybotrys chartarum macrocyclic trichothecene mycotoxins on particulates

smaller than conidia. Applied and Environmental Microbiology 2005; 71(1): 114-

122.

3. Gorny RL, Reponen T, Willeke K, Schmechel D, Robine E, Boissier M,

Grinshpun SA. Fungal fragments as indoor air biocontaminants. Applied and

Environmental Microbiology 2002; 3522-3531.

4. Gorny RL. Filamentous microorganisms and their fragments in indoor air- a

review. Ann Agric Environ Med 2004; 11: 185-197.

5. Panaccione DG, Coyle CM. Abundant respirable ergot alkaloids from the

common airborne fungus Aspergillus fumigatus. Applied and Environmental

Microbiology 2005; 71(6): 3106-3111.

6. Schulz T, Senkpiel K, Ohgke H. Comparison of the toxicity of reference

mycotoxins and spore extracts of common indoor moulds. International Journal of

Hygiene and Environmental Health 2004; 207(3): 267-277.

Actinomycetes

1. Penttinen P, Pelkonen J, Huttunen K, Hirvonen MR. Co-cultivation of

Streptomyces of Streptomyces californicus and Stachybotrys chartarum stimulates

the production of cytostatic compound(s) with immunotoxic properties.

Toxicology and Applied Pharmacology 2006; 217: 342-351.

2. Gorny RL, Mainelis G, Grinshpun SA, Willeke K, Dutkiewicz J, Reponen T.

Release of Streptomyces albus propagules from contaminated surfaces.

Environmental Research 2003; 91: 45-53.

3. Huttunen K, Pelkonen J, Nielsen KF, Nuutinen U, Jussila J, Hirvonen MR.

Synergistic interaction in simultaneous exposure to Streptomyces

californicus and

Stachybotrys chartarum. Environmental Health Perspectives 2004; 112(4): 659-

665.

4. ez A, Kolvek SJ, Hopke J, Yip CLT, Osburne MS. Environmental DNA

fragments conferring early and increased sporulation and antibiotic

production in

Streptomyces species. Applied and Environmental Microbiology 2005; 71(3):

1638-1641.

5. Murtoniemi T, Penttinen P, Nevalainen A, Hirvonen MR. Effects of microbial

cocultivation on inflammatory and cytotoxic potential of spores. Inhal Toxicol

2005; 17(12): 681-693.

6. Penttinen P, Huttunen K, Pelkonen J, Hirvonen MR. The proportions of

Streptomyces californicus and Stachybotrys chartarum in simultaneous exposure

affect inflammatory responses in mouse RAW264.7 macrophages. Inhal Toxicol

2005; 17(2): 79-85.

Bacteria/Endotoxin

1. Buttner MP, Cruz- P, Stetzenbach LD. Enhanced detection of

surfaceassociated

bacteria in indoor environments by quantitative PCR. Applied and

Environmental Microbiology 2001; 67(6): 2564-2570.

2. Inoue KI, Takno H, Yanagisawa R, Hirano S, Sakurai M, Shimada A, Yoshikawa

T. Effects of airway exposure to nanoparticles on lung inflammation induced by

bacterial endotoxin in mice. Environmental Health Perspectives 2006; 114(9):

1325-1330.

3. Peltola J, Andersson MA, Haahtela T, Mussalo-Rauhamaa H, Rainey FA,

Kroppenstedt RM, Samson RA, Salkinoja-Salonen MS. Toxic-metaboliteproducing

bacteria and fungus in an indoor environment. Applied and

Environmental Microbiology 2001; 67(7): 3269-3274.

4. Gandara A, Mota LC, C, HR, Green CF, Gibbs SG. Isolation of

Staphylococcus aureus and antibiotic-resistant Staphylococcus aureus from

residential indoor bioaerosols. Environmental Health Perspectives 2006; 114(12):

1859-1864.

5. Zughaier SM, Zimmer SM, Datta A, Carlson RW, s DS. Differential

induction of Toll-like receptor 4-MyD88-dependent and –independent signaling

pathways by endotoxins. Infect Immun 2005; 73(5): 2940-2950.

6. Medvedev AE, Lentschat A, Wahl LM, Golenbock DT, Vogel SN. Dysregulation

of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1

receptor-associated kinase 1 activation in endotoxin-tolerant cells. J Immunol

2002; 169(9): 5209-5216.

7. Dobrovolskaia MA, Medvedev AE, KE, Cuesta N, Toshchakov V, Ren

T, Cody MJ, Michalek SM, Rice NR, Vogel SN. Induction of in vitro

reprogramming by Toll-like receptor (TLR) 2 and TLR4 agonists in murine

macrophages: effects of TLR " homotolerance " versus " heterotolerance " on NFkappa

B signaling pathway components. J Immunol 2003; 170(1): 508-519.

8. Zhou HR, Harkema JR, Hotchkiss JA, Yan D, Roth RA, Pestka JJ.

Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol)

synergistically induce apoptosis in murine lymphoid organs. Toxicol Sci 2000;

53(2): 253-263.

9. Islam Z, Moon YS, Zhou HR, King LE, er PJ, Pestka JJ. Endotoxin

potentiation of trichothecene-induced lymphocyte apoptosis is mediated

by upregulation

of glucocorticoids. Toxicol Appl Pharmacol 2002; 180(1): 43-55.

10. Islam Z, King LE, Fraker PJ, Pestka JJ. Differential induction of

glucocorticoiddependent

apoptosis in murine lymphoid subpopulations in vivo following

coexposure to lipopolysaccharide and vomitoxin (deoxynivalenol). Toxicol Appl

Pharmacol 2003; 182(2): 69-99.

11. Islam Z, Pestka JJ. Role of IL-1beta in endotoxin potentiation of

deoxynivalenolinduced

corticosterone response and leukocyte apoptosis in mice. Toxicol Sci

2003; 74(1): 93-102.

12. Hirvonen MR, Huttunen K, Roponen M. Bacterial strains from moldy buildings

are highly potent inducers of inflammatory and cytotoxic effects.

Indoor Air 2005; 15

Suppl 9: 65-70.

Environmental RX Health Problems

1. Menzies D, Popa J, Hanley JA, Rand T, Milton DK. Effect of ultraviolet

germicidal lights installed in office ventilation systems on worker's health and

wellbeing: double-blind multiple crossover trial. The Lancet 2003; 362: 1785-

1791.

2. SC, Wu C, Andriychuk LA, JM, Brasel TL, Jumper CA, Straus

DC. Effect of chlorine dioxide gas on fungi and mycotoxins associated with sick

building syndrome. Applied and Environmental Microbiology 2005; 71(9): 5399-

5403.

3. Kercsmar CM, Dearborne DG, Schluchter M, Xue L, Kirchner L, Sobolewski J,

Greenberg SJ, Vesper SJ, Allan T. Reduction in asthma morbidity in children as a

result of home remediation aimed at moisture sources. Environmental Health

Perspectives 2006; 114(8): 1574-1580.

4. Levetin E, Shaughnessy R, CA, Scheir R. Effectiveness of germicidal UV

radiation for reducing fungal contamination within air-handling units. Applied

and Environmental Microbiology 2001; 67(8): 3712-3715.

5. Bourbeau J, Brisson C, Allaire S. Prevalence of the sick building syndrome

symptoms in office workers before and after being exposed to a building with an

improved ventilation system. Occupational and Environmental Medicine 1996;

53: 204-210.

Brain and Neuro Injury

1. LJ, Doebler JA, A. Scanning cytophotometric analysis of brain

neuronal nuclear chromatin changes in acute T-2 toxin-treated rats. Toxicol Appl

Pharmacol 1986; 85(2): 207-214.

2. LJ, Morse JD, A. Quantitative cytophotometric

analysis of brain

neuronal RNA and protein changes in acute T-2 mycotoxin poisoned rats.

Toxicon 1986; 24(9): 933-941.

3. Schoental R. Fusarial mycotoxins and behaviour: possible implications for

psychiatric disorder. Br J Psychiatry 1985; 146: 115-119.

4. Wang J, Fitzpatrick DW, JR. Effect of T-2 toxin on blood-brain barrier

permeability monoamine oxidase activity and protein synthesis in rats. Food

Chem Toxicol 1998; 36(11): 955-961.

5. Patton DE, Duff K, Schoenberg MR, Mold J, JG, RL. Base rates of

longitudinal RBANS discrepancies at one- and two-year intervals in

communitydwellings

older adults. Clin Neuropsychol 2005; 19(1): 27-44.

6. Baldo JV, Ahmad L, Ruff R. Neuropsychological performance of patients

following mold exposure. Appl Neuropsychol 2002; 9(4): 193-202.

7. Kilburn KH. Indoor mold exposure associated with neurobehavioral and

pulmonary impairment: a preliminary report. Arch Environ Health 2003; 58(7):

390-398.

8. Rea WJ, Didriksen N, Simon TR, Pan Y, Fenyves EJ, Griffiths B.

Effects of toxic

exposure to molds and mycotoxins in building-related illnesses. Arch Environ

Health 2003; 58(7): 399-405.

9. Gordon WA, Cantor JB, Johanning E, Charatz H, Ashman TA, Breeze JL,

Haddad L, Abramowitz S. Cognitive impairment associated with toxigenic fungal

exposure: a replication and extension of previous findings. Applied

Neuropsychology 2004; 11(2): 65-74.

10. Sava V, Velasquez A, Reunova O, -Ramos J. Acute ochratoxin-A

neurotoxicity: kinetics of distribution of the toxin, indices of

oxidative stress and

DNA repair activities in mouse brain. Accepted Abstract for Platform

Presentation Society for Neuroscience, Annual Meeting Washington DC,

November 2005.

11. -Ramos J, Sava V. Mycotoxins: can low level, non-lethal

exposure result

in Parkinsonism? Abstract of invited lecture presented at Worlds Federation of

Neurology, Symposium on Neurotoxicology, Sydney, Australia 11/2005.

12. Bergmann F, Yagen B, Jarvis BB. The toxicity of macrocyclic trichothecenes

administered directly into the rat brain. Toxicons 1992; 30(10): 1291-1294.

13. Crago BR, Gray MR, LA, M, Arnold L, Thrasher JD.

Psychological, neuropsychological, and electrocortical effects of mixed mold

exposure. Archives of Environmental Health 2004; 452-462.

14. Kilburn KH. Indoor mold exposure associated with neurobehavioral and

pulmonary impairment: a preliminary report. PubMed 2004.

15. Gordon KE, Masotti RE, Waddell WR. Tremorgenic encephalopathy: a role of

mycotoxins in the production of CNS disease in humans? Can J Neurol Sci 1993;

20: 237-239.

16. Fung F, R, S. Stachybotrys, a mycotoxin-producing fungus of

increasing toxicologic importance. Clinical Toxicology 1998; 36(1 & 2): 76-86.

17. Cooley JD, Wong WC, Jumper CA, Straus DC. Correlation between the

prevalence of certain fungi and sick building syndrome. Occup Environ Med

1998; 55: 579-584.

Gene Expression

1. Nielsen KF, Huttunen K, Hyvarinen A, Andersen B, Jarvis BB, Hirvonen MR.

Metabolite profiles of Stachybotrys isolates from water-damaged buildings and

their induction of inflammatory mediators and cytotoxicity in macrophages.

Mycopathologia 2002; 154(4): 201-205.

2. Trinchieri G, Sher A. ation of Toll-like receptor signals in

innate immune

defence. Nature Reviews Immunology 2007; 7: 179-190.

3. Romani L. Immunity to fungal infections. Nature Reviews Immunology 2004; 4:

1-13.

4. Hudson B, Flemming J, Sun G, Rand TG. Comparison of immunomodulator

mRNA and protein expression in the lungs of Stachybotrys chartarum sporeexposed

mice. J Toxicol Environ Health A 2005; 68(15): 1321-1335.

5. Yike I, Rand T, Dearborn DG. The role of fungal proteinases in

pathophysiology

of Stachybotrys chartarum. Mycopathologia 2007; July 3 PMID 17610048

6. Rao KMK, Ma JYC, Meighan T, Barger MW, Pack D, Vallyathan V. Time

course of gene expression of inflammatory mediators in rat lung after diesel

exhaust particle exposure. Environmental Health Perspectives 2005; 113(5): 612-

617.

7. Flach CF, Qudri F, Bhuiyan TR, Alam NH, Jennische E, Lonnroth I, Holmgren J.

Broad up-regulation of innate defense factors during acute cholera.

Infection and

Immunity 2007; 75(5): 2343-2350.

8. JC, Dechraoui MYB, Morey JS, Rezvani A, Levin ED, Gordon CJ,

Ramsdell JS, van Dolah FM. Genomic and proteomic analysis of whole blood in

mice exposed to the marine neurotoxin Pacific ciguatoxin-1.

9. Kim JM, Kim JS, Lee JY, Kim YJ, Youn NJ, Lim IY, Chee YJ, Oh YK, Kim N,

Jung HC, Song IS. Vacuolating cytotoxin Helicobacter pylori water-soluble

protein upregulates chemokine expression in human eosinophils via Ca2+ influx,

mitochondrial reactive oxygen intermediates, and NF-kB activation. Infection and

Immunity 2007; 75(7): 3373-3381.

10. Pestka JJ, Yan D, King LE. Flow cytometric analysis of the effects

of in vitro

exposure to vomitoxin (deoxynivalenol) on apoptosis in murine T, B and IgA+

cells. Food Chem Toxicol 1994; 32(12): 1125-1136.

11. Poapolathep A, Ohtsuka R, Kiaptipattanasakul W, Ishigami N, Nakayana H, Doi

K. Nivalenol-induced apoptosis in thymus, spleen and Peyer's patches of mice.

Exp Toxicol Pathol 2002; 53(6): 441-446.

12. Islam Z, Gray JS, Pestka JJ. P38 Mitogen-activated protein kinase

mediates IL-8

induction by the ribotoxin deoxynivalenol in human monocytes. Toxicol Appl

Pharmacol 2006; 213(3): 235-244.

13. Leino M, Makela M, Reijula K, Haahtela T, Mussalo-Rauhamaa H, Tuomi T,

Hintikka EL, Alenius H. Intranasal exposure to a damp building mould,

Stachybotrys chartarum, induces lung inflammation in mice by

satratoxinindependent

mechanisms. Clin Exp Allergy 2003; 33(11): 1603-1610.

14. Huttunen K, Hyvarinen A, Nevalainen A, Komulainen H, Hirvonen MR.

Production of proinflammatory mediators by indoor air bacteria and fungal spores

in mouse and human cell lines. Environ Health Perspect 2003; 111(1): 85-92.

15. Dong W, Azcona-Olivera JI, KH, Linz JE, Pestka JJ. Elevated gene

expression and production of interleukins 2, 4, 5, and 6 during exposure to

vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma. Toxicol

Appl Pharmacol 1994; 127(2): 282-290.

16. Ouyang YL, Azcona-Olivera JI, Murtha J, Pestka JJ. Vomitoxin-mediated IL-2,

IL-4, and IL-5 superinduction in murine CD4+ T cells stimulated with phorbol

ester calcium ionophore: relation to kinetics of proliferation. Toxicol Appl

Pharmacol 1996; 138(2): 324-334.

17. Zhou HR, Harkema JR, Yan D, Pestka JJ. Amplified proinflammatory cytokine

expression and toxicity in mice co-exposed to lipopolysaccharide and the

trichothecene vomitoxin (deoxynivalenol). J Toxicol Environ Health A 1999;

57(2): 115-136.

18. Wong SS, Zhou HR, Marin-ez ML, K, Pestka JJ. Modulation of

IL1-beta, IL-6 and TNF-alpha secretion and mRNA expression by the

trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line. Food

Chem Toxicol 1998; 36(5): 409-419.

19. Chung YJ, Jarvis B, Pestka J. Modulation of lipopolysaccharide-induced

proinflammatory cytokine production by satratoxins and other macrocyclic

trichothecenes in the murine macrophage. J Toxicol Environ Health A 2003;

66(4): 379-391.

20. Sugita-Konishi Y, Pestka JJ. Differential upregulation of

TNF-alpha. IL-6, and

IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in

a human macrophage model. J Toxicol Environ Health A 2001; 64(8): 619-636.

21. Chung YJ, Jarvis B, Pestka J. Modulation of lipopolysaccharide-induced

proinflammatory cytokine production by satratoxins and other macrocyclic

trichothecenes in the murine macrophage. J Toxicol Environ Health A 2003;

66(4): 379-391.

22. Islam Z, Pestka JJ. LPS priming potentiates and prolongs proinflammatory

cytokine response to the trichothecene deoxynivalenol in the mouse. Toxicology

and Applied Pharmacology 2006; 211: 53-63.

23. Chung YJ, Yang GH, Islam Z, Pestka JJ. Up-regulation of macrophage

inflammatory protein-2 and complement 3A receptor by the trichothecenes

deoxynivalenol and satratoxin G. Toxicology 2003; 186: 51-65.

24. Wang H, Yadav JS. Global gene expression changes underlying Stachybotrys

chartarum toxin-induced apoptosis in murine alveolar macrophages: evidence of

multiple signal transduction pathways. Apoptosis 2007; 12(3): 535-548.

25. Pestka J, Zhou HR. Toll-like receptor priming sensitizes macrophages to

proinflammatory cytokine gene induction by deoxynivalenol and other toxicants.

Toxicol Sci 2006; 92(2): 445-455.

26. Zhou HR, Islam Z, Pestka JJ. Induction of competing apoptotic and survival

signaling pathways in the macrophage by the ribotoxic trichothecene

deoxynivalenol. Toxicol Sci 2005; 87(1): 113-122

27. Zhou HR, Jia Q, Pestka JJ. Ribotoxic stress response to the trichothecene

deoxynivalenol in the macrophage involves the SRC family kinase Hck. Toxicol

Sci 2005; 85(2): 916-926.

28. Kinser S, Li M, Jia Q, Pestka JJ. Truncated deoxynivalenol-induced splenic

immediate early gene response in mice consuming (n-3) polyunsaturated fatty

acids. J Nutr Biochem 2005; 16(2): 88-95.

29. Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and

cytokine production in

the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein

kinases and comparison to other 8-ketotrichothecenes. Toxicology 2005; 206(2):

207-219.

30. Nusuetrong P, Yoshida M, Tanitsu MA, Kikuchi H, Mizugaki M, Shimazu K,

Pengsuparp T, Meksuriyen D, Oshima Y, Nakahata N. Involvement of reactive

oxygen species and stress-activated MAPKs in satratoxin H-induced apoptosis.

Eur J Pharmacol 2005; 507(1-3): 239-246.

31. Jia Q, Zhuo HR, Bennink M, Pestka JJ. Docosahexaenoic acid attenuates

mycotoxin-induced immunoglobulin A nephropathy, interleukin-6 transcription,

and mitogen-activated protein kinase phosphorylation in mice. J Nutr 2004;

134(12): 3343-3349.

32. Moon Y, Pestka JJ. Deoxynivalenol-induced mitogen-activated protein kinase

phosphorylation and IL-6 expression in mice suppressed by fish oil. J Nutr

Biochem 2003; 14(12): 717-726.

33. Chung YZ, Zhou HR, Pestka JJ. Transcriptional and

posttranscriptional roles for

p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by

deoxynivalenol (vomitoxin). Toxicol Appl Pharmacol 2003; 193(2): 188-201

34. Deva R, Shankaranarayanan P, Ciccoli R, Nigam S. Candida albicans induces

selectively transcriptional activation of cyclooxygenase-2 in HeLa

cells: pivotal

roles of Toll-like receptors, p38 mitogen-activated protein kinase, and NF-kappa

B. J Immunol 2003; 171(16): 3047-3055.

35. Zhou HR, Lau AS, Pestka JJ. Role of double-stranded RNA-activated protein

kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. Toxicol Sci

2003; 74(2): 335-344.

36. Moon Y, Pestka JJ. Vomitoxin-induced cyclooxygenases 2 gene expression in

macrophages mediated by activation of ERK and p38 but not JNK mitogenactivated

protein kinases. Toxicol Sci 2002; 69(2): 373-382.

37. Moon Y, Uzarski R, Pestka JJ. Relationship of trichothecene

structure to COX-2

induction in the macrophage: selective action of type B (8-keto)

trichothecenes. J

Toxicol Environ Health A2003; 66(20): 1967-1983.

38. Yang GH, Jarvis BB, Chung YJ, Pestka JJ. Apoptosis induction by

the satratoxins

and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and

SAPK/JNK activation. Toxicol Appl Pharmacol 2000; 164(2): 149-160.

39. Shifrin VI, P. Trichothecene mycotoxins trigger a ribotoxic stress

response that activates c-Jun N-terminal kinase and p38

mitogen-activated protein

kinase and induces apoptosis. J Biol Chem 1999; 274(20): 13985-13992.

Beta Glucans

1. Young SH, JR, Antonini JM. Pulmonary exposure to 1, 3-beta-glucan

alters adaptive immune responses in rats. Inhal Toxicol 2006; 18(11): 865-874.

2. Thorn J, Rylander R. Airways inflammation and glucan in a rowhouse area. Am J

Respir Crit Care Med 1998; 157: 1798-1803.

3. Young SH, JR, Antonini JM. Pulmonary exposure to 1, 3-B-glucan alters

adaptive immune responses in rats. Inhalation Toxicology 2006; 18: 865-874.

4. Brown GD. Dectin-1: a signaling non-TLR pattern-recognition receptor. Nature

Reviews Immunology 2006; 6: 33-43.

5. MJ, Sancho D, Slack EC, LeibundGut-Landmann S, Sousa CR.

Myeloid C-type lectins in innate immunity. Nature Immunology 2006; 7(12):

1258-1264.

6. McCann F, Carmona E, Puri V, Pagano RE, Limper AH. Macrophage

internalization of fungal-B-glucans is not necessary for initiation of related

inflammatory responses. Infection and Immunity 2005; 73(10): 6340-6349.

7. Kataoka K, Muta T, Yamazaki S, Takeshige K. Activation of macrophages by

linear (1,3)-beta-D-glucans. Implications for the recognition of fungi by innate

immunity. J Biol Chem 2002; 277(39): 36825-36831.

8. Palma AS, Feizi T, Zhang Y, Stoll MS, Lawson AM, - E,

Campanero- MA, Costa J, Gordon S, Brown GD, Chai W. Ligands for the

beta-glucan receptor, dectin-1, assigned using " designer " microarrays of

oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides. J

Biol Chem 2006; 281(9): 5771-5779.

9. Herre J, Willment JA, Gordon S, Brown GD. The role of dectin-1 in antifungal

immunity. Crit Rev Immunol 2004; 24(3): 193-203.

10. PR, Tsoni SV, Willment JA, KM, s M, Findon H, Haynes

K, Steele C, Botto M, Gordon S, Brown GD. Dectin-1 is required for beta-glucan

recognition and control of fungal infection. Nat Immunol 2007; 8(1): 31-38.

11. Willment JA, Marshall AS, Reid DM, DL, Wong SY, Gordon S, Brown

GD. The human beta-glucan receptor is widely expressed and functionally

equivalent to murine dectin-1 on primary cells. Eur J Immunol 2005; 35(5): 1539-

1547.

12. PR, Brown GD, Reid DM, Willment JA, ez-Pomares L, Gordon S,

Wong SY. The beta-glucan receptor, dectin-1, is predominantly expressed on the

surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol

2002; 169(7): 3879-3882.

13. Brown GD, PR, Reid DM, Willment JA, DL, ez-Pomares

L, Wong SY, Gordon S. Dectin-1 is a major beta-glucan receptor on

macrophages. J Exp Med 2002; 196(3): 407-412.

14. Thornton BP, Vetvicka V, Pitman M, Goldman RC, Ross GD. Analysis of the

sugar specificity and molecular location of the beta-glucan-binding

lectin site of

complement receptor type 3 (CD11b/CD18). J Immunol 1996; 156(3): 1235-

1246.

15. Ozment-Skelton TR, Goldman MP, Gordon S, Brown GD, DL.

Prolonged reduction of leukocyte membrane-associated dectin-1 levels following

beta-glucan administration. J Pharmacol Exp Ther 2006; 318(2): 540-546.

16. Herre J, Gordon S, Brown GD. Dectin-1 and its role in the

recognition of betaglucans

by macrophages. Mol Immunol 2004; 40(12): 869-876.

17. Adachi Y, Ishii T, Ikeda Y, Hoshino A, Tamura H, Aketagawa J, Tanaka S, Ohno

N. Characterization of beta-glucan recognition site on C-type lectin, dectin 1.

Infect Immun 2004; 72(7): 4159-4171.

18. McGreal EP, s M, Brown GD, Zamze S, Wong SY, Gordon S, ez-

Pomares L, PR. The carbohydrate-recognition domain of dectin-2 is a Ctype

lectin with specificity for high mannose. Glycobiology 2006; 16(5): 422-430.

Inflammation

1. Netea MG, Van der Meer JWM, Sutmuller RP, Adema GJ, Kullberg BJ. From the

Th1/Th2 paradigm towards a Toll-like receptor/T-helper bias. Antimicrobial

Agents and Chemotherapy 2005; 49(10): 3991-3996.

2. Islam Z, Harkems JR, Pestka JJ. Satratoxin G from the black mold Stachybotrys

chartarum evokes olfactory sensory neuron loss and inflammation in the murine

nose and brain. Envir Health Perpe 2006; 114(7): 1099-1107.

3. Islam Z, Amuzie CJ, Harkema JR, Pestka JJ. Neurotoxicity and inflammation in

the nasal airways of mice exposed to the macrocyclic trichothecene mycotoxins

roridin A: kinetics and potentiation by bacterial lipopolysaccharide

co-exposure.

ToxSci Advance Access May 2004.

4. Creasia DA, Thurman JD, LJ, Nealley ML, York CG, Wannemacher RW,

Bunner DL. Acute inhalation toxicity of T-2 mycotoxin in mice. Fundamental and

Applied Toxicology 1987; 8: 230-235.

5. Rand TG, Flemming J, JD, Womiloju TO. Comparison of inflammatory

responses in mouse lungs exposed to atranones A and C from Stachybotrys

chartarum. Journal of Toxicology and Environmental Health 2006; 69: 1-13.

6. van der Graff CAA, Netea MG, Verschueren I, van der Meer JWM, Kullberg BJ.

Differential cytokine production and Toll-like receptor signaling pathways by

Candida albicans blastoconidia and hyphae. Infection and Immunity 2005; 73(11):

7458-7464.

7. A, Van Epps HL, Hohl TM, Rizzuto G, Pamer EG. Distinct CD4+-T-cell

responses to live and heat-inactivated Aspergillus fumigatus conidia. Infection

and Immunity 2005; 73(11): 7170-7179.

8. Huttunen K, Hyvarinen A, Nevalainen A, Komulainen H, Hirvonen MR.

Production of proinflammatory mediators by indoor air bacteria and fungal spores

in mouse and human cell lines. Environmental Health Perspectives 2003; 111(1):

85-92.

9. Jiang H, Chess L. Regulation of immune responses by T cells. N Engl J Med

2006; 354: 1166-1176.

10. Kay AB. Natural Killer T cells and asthma. N Engl J Med 354(11): 1186-1188.

11. Akbari O, Faul JL, Hoyte EG, Berry GJ, Wahlstrom J, Kronenberg M, DeKruyff

RH, Umestsu DT. CD4+ invariant T-cell-receptor+ natural killer T cells in

bronchial asthma. N Engl J Med 2006; 354(11): 1117-1129.

12. Flemming J, Hudson B, Rand TG. Comparison of inflammatory and cytotoxic

lung responses in mice after intratracheal exposure to spores of two different

Stachybotrys chartarum strains. Toxicological Sciences 2004; 78: 267-275.

13. Stoeger T, Reinhard C, Takenaka S, Schroeppel A, Karg E, Ritter B, Heyder J,

Schulz H. Instillation of six different ultrafine carbon particles

indicates a surface

area threshold dose for acute lung inflammation in mice. Environmental Health

Perspectives 2006; 114(3): 328-333.

14. Veranth JM, Moss TA, Chow JC, Labban R, Nichols WK, Walton JC,

JG, Yost GS. Correlation of in vitro cytokine responses with the chemical

composition of soil-derived particulate matter. Environmental Health

Perspectives

2006; 114(3): 341-349.

15. Nurkiewicz TR, Porter DW, Barger M, Millecchia L, Rao MK, Marvar PJ, Hubbs

AF, Castranova V, Boegehold MA. Systemic microvascular dysfunction and

inflammation after pulmonary particulate matter exposure. Environmental Health

Perspectives 2006; 114(3): 412-419.

16. Rand TG, Giles S, Flemming J, JD, Puniani E. Inflammatory

and cytotoxic

responses in mouse lungs exposed to purified toxins from building isolated

Penicillium brevicompactum dierckx and p. chrysogenum thom. Toxicological

Sciences 2005; 87(1): 213-222.

17. Donohue M, Wei W, Wu J, Zawia NH, Hud N, De Jesus V, Schmechel D, Hettick

JM, Beezhold DH, Vesper S. Characterization of nigerlysin c, hemolysin

produced by Aspergillus niger, and effect on mouse neuronal cells in vitro.

Toxicology 2006; 219: 150-155.

18. Rao CY, Burge HA, Brain JD. The time course of responses to intratracheally

instilled toxic Stachybotrys chartarum spores in rats. Mycopathologia 2000; 149:

27-34.

19. Marc MM, Korosec P, Kosnick M, Kern I, Flezar M, Suskovic S, Sorli J.

Complement factors C3a, C4a, and C5a in chronic obstructive pulmonary disease

and asthma. American J of Respir Cell and Molecular Biology 2004; 31: 31-33.

20. Arason GJ, Kolka R, Hreidarsson AB, Gudjonsson H, Schneider PM, Fry L,

Arnason A. Defective prevention of immune precipitation in autoimmune diseases

is independent of C4a*Q0. British Society for Immunology, Clinical and

Experimental Immunology 2005; 140: 572-579.

21. Kelk P, Claesson R, Hanstrom L, Lerner UH, Kalfas S, Johansson A. Abundant

secretion of bioactive interleukin-1b by human macrophages induced by

Actinobacillus actinomycetemcomitans leukotoxins. Infection and Immunity

2005; 73(1): 453-458.

22. Romani L. Immunity to fungal infections. Nature Reviews Immunology 2004; 4:

11-23.

23. Kohl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J,

Herman NS, Sproles AA, Zwirner J, Whirsett JA, Gerard C, Sfyroera G, Lambris

JD, Wills-Karp M. A regulatory role for the C5a anaphylatoxins in type 2

immunity in asthma. Journal of Clinical Investigation 2006; 116(3): 783-796.

24. Desjardins AE. Trichothecenes: from yellow rain to green wheat. ASM News

2003; 69(4): 182-185.

25. McCrae KC, Rand T, Shaw RA, Mason C, Oulton MR, Hastigns C, Cherlet T,

Thliveris JA, Mantsch HH, Mac J, JE. Analysis of pulmonary

surfactant by Fourier-transform infrared spectroscopy following exposure to

Stachybotrys chartarum (atra) spores. Chemistry and Physics of Lipids 2001; 110:

1-10.

26. Donohue M, Wei W, Wu J, Zawia NH, Hud N, De Jesus V, Schmechel D, Hettick

JM, Beezhold DH, Vesper S. Nigerlysin, hemolysin produced by Aspergillus

niger, causes lethality of primary rat cortical neuronal cells in

vitro. 09/02/05; 1-

27. Vesper SJ, Vesper MJ. Possible role of fungal hemolysins in sick building

syndrome. Advances in Applied Microbiology 2004; 55: 191-213.

28. Jussila JJ. Inflammatory responses in mice after intratracheal

instillation of

microbes isolated from moldy buildings. PhD dissertation 01/24/03 National

Public Health Institute, Finland.

29. Vesper SJ, Vesper MJ. Stachylysin may be a cause of hemorrhaging in humans

exposed to Stachybotrys chartarum. Infection and Immunity 2002; 70(4): 2065-

2069.

30. Mason CD, Rand TG, Oulton M, Mac JM, JE. Effects of

Stachybotrys chartarum (atra) conidia and isolated toxin on lung surfactant

production and homeostasis. Natural Toxins 1998; 6: 27-33.

31. Nikulin M, Reijula K, Jarvis BB, Veijalainen P, Hintikka EL.

Effects of intranasal

exposure to spores of Stachybotrys atra in mice. Fundamental and Applied

Toxicology 1997; 35: 182-188.

32. Wilkins CK, Larsen ST, Hammer M, Poulsen OM, Wolkoff P, Nielsen GD.

Respiratory effects in mice exposed to airborne emissions from Stachybotrys

chartarum and implications for risk assessment. Pharmacology & Toxicology

1998; 83: 112-119.

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