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Bronchiolitis Obliterans Organizing Pneumonia

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Bronchiolitis Obliterans Organizing Pneumonia

R. Epler, M.D.

Harvard Medical School

Pulmonary and Critical Care Medicine

Brigham and Women's Hospital

Boston, Massachusetts

Environment-related BOOP continues to be reported rarely. In 1992,

textile printing dye-related BOOP was described in 22 textile

airbrush workers.69 Six died initially. Follow-up of some of the

workers indicated gradual improvement over time.70 It has been

suggested69 that the cause was related to the spraying of a

respirable aerosol into the distal airways and alveoli; however,

the reactive chemical agent and mechanism remain unclear. It is

also not known whether the organizing pneumonia was a de novo

process or resulted from the late organization of pulmonary

edema.69 Penicillium mold dust-related BOOP has been described71

in a patient who developed BOOP after inhalation of powdery dust of

a growth of Penicillium janthinellum mold on the top of a discarded

orange juice container. Smoke inhalation BOOP has

been reported72 in a patient who was in a house fire and had

erythema nodosum.

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Bronchiolitis Obliterans Organizing Pneumonia

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