Guest guest Posted August 17, 2007 Report Share Posted August 17, 2007 Sewage-flooded Winnipeg residents raise cleanup concerns CBC Manitoba - Winnipeg,Manitoba,Canada* Friday, August 17, 2007 http://www.cbc.ca/canada/manitoba/story/2007/08/17/sewage-flood.html Winnipeggers whose home basements were flooded with sewage due to a city error in July are concerned about the effectiveness of the cleanup and the possibility of lingering mould and bacteria. As much as a metre of sewage water backed up into more than 50 homes in the area around Assiniboine Avenue and Ferry Road on July 25. City officials accepted responsibility for the flooding, admitting a municipal crew working in the area had failed to reopen a gate that would have drained the sewage into the river during the storm. Three weeks later, some of the residents have refused to return to their homes, saying they are not convinced that mould and other contaminants have been properly removed. Several homeowners complain the city has not discussed what level of cleanliness is acceptable, nor has the city done any air-quality testing or followed up with them about health issues. Mould, odours in homes and said the city's response was great in the week after the flood. A city-approved company quickly cleaned and decontaminated the basement of his home on Ferry Road. But when the couple returned to the home, said his wife, who has lupus, a chronic autoimmune disease, had a reaction immediately. " When she comes back in, in about 10 minutes minimum, she is coughing. She can't handle the environment, " he told CBC News. " For sure I'm going to have to pull out the studs here, for the sake of my wife's health, and probably my own. " Several of the 's neighbours have similar stories of health issues or persistent odours. " It was only after everybody else was coming in my house and saying, 'Yes, your house stinks,' that I think, 'OK, we've got a problem,' " said Joan Cummings of her home on Roseberry. Cummings had her home tested; the tests showed unacceptably high levels of a type of mould that can be dangerous. " I feel like, am I the one responsible for investigating all this to understand? " she said. " Sometimes when I ask people [things], they don't know, so I just feel like, 'OK, this is my home. It's maybe my responsibility to make sure it's safe and find out what the right procedures are.' " Air quality testing offered City officials said they will test the air quality in the homes of anyone affected by the sewage backup. " We are on the case, " city spokesman Ken said after he was contacted by CBC about the homeowners' concerns. " We take these concerns very seriously, and we will be testing air quality in the homes where there are concerns. " Homeowners who want the testing done should contact their adjustor to arrange for testing, said. Dr. Tim Hilderman, a provincial medical officer of health, said air- quality testing is just one piece of the puzzle. " I think the only way you know for sure is — regardless of what air quality is telling you — is that you have to have the complete visual inspection to ensure there is no sources of on0going mould. " Air conditioning and heating systems will also have to be examined, he said, and if homeowners are still unsure, they should consult an expert. " Certainly I would encourage them to contact their local public health unit and talk to a public health inspector. " So far, three homeowners have taken up the offer for air-quality testing, city officials said. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 18, 2007 Report Share Posted August 18, 2007 * *Mold and bacteria together.. a match made in hell...<javascript:AL_get(this, 'jour', 'J Toxicol Environ Health A.');> J Toxicol Environ Health A. <javascript:AL_get(this, 'jour', 'J Toxicol Environ Health A.');> 2003 Feb 28;66(4):379-91.Links<javascript:PopUpMenu2_Set(Menu12554543);> Modulation of lipopolysaccharide-induced proinflammatory cytokine production by satratoxins and other macrocyclic trichothecenes in the murine macrophage.*Chung YJ*<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22Chung%\ 20YJ%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubme\ d_RVAbstractPlus>, *Jarvis B*<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22Jarvis%\ 20B%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed\ _RVAbstractPlus>, *Pestka J*<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22Pestka%\ 20J%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed\ _RVAbstractPlus> .. Department of Food Science and Human Nutrition, Institute for Environmental Toxicology, Michigan State University, East Lansing, Michigan 48824-224, USA. The satratoxins and other macrocyclic trichothecene mycotoxins are produced by Stachybotrys, a mold that is often found in water-damaged dwellings and office buildings. To test the potential immunomodulatory effects of these mycotoxins, RAW 264.7 murine macrophage cells were treated with various concentrations of satratoxin G (SG), isosatratoxin F (iSF), satratoxin H (SH), roridin A (RA), and verrucarin A (VA) for 48 h in the presence or absence of suboptimal concentra-tion of lipopolysaccharide (LPS, 50 ng/ml), and tumor necrosis factor-alpha (TNF-alpha ) and interleukin-6 (IL-6) production were assayed by enzyme-linked immunosorbent assay (ELISA). In LPS-stimulated cultures, TNF-alpha supernatant concentrations were significantly increased in the presence of 2.5, 2.5, and 1 ng/ml of SG, SH, and RA, respectively, whereas IL-6 concentrations were not affected by the same concentrations these macrocyclic trichothecenes. When cells that were treated with LPS and SG (2.5 ng/ml) were evaluated by real-time polymerase chain reaction (PCR),TNF-alpha mRNA was found to increase at 24, 36, and 48 h compared to control cells. At higher concentrations, cytokine production and cell viability were markedly impaired in LPS-stimulated cells. Without LPS stimulation, neither TNF-alpha, nor IL-6 was induced. These results indicate that low concentrations of macrocyclic trichothecenes superinduce expression of TNF-alpha, whereas higher concentrations of these toxins are cytotoxic and concurrently reduce cytokine production. The capacity of satratoxins and other macrocyclic trichothecenes to alter cytokine production may play an etiologic role in outbreaks of Stachybotrys-associated human illnesses. PMID: 12554543 [PubMed - indexed for MEDLINE] Quote Link to comment Share on other sites More sharing options...
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