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Re: Vitamin B6: Neurotoxicology

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That's weird. The nervous system runs on all B vitamins unless 'Pyridoxine' is

an artificial version of B6. (I don't know.....never heard of Pyridoxine

before.) Vitamin B6 from a natural source is certainly not neurotoxic.

Betsy

gsgrl2000 <gsgrl2000@...> wrote:

In table 1 from the article Biochemical and Molecular Neurotoxicology

(chapter 18 & 19); Introduction to Biochemical Toxicology (third

edition, 2000) E. Hodgson and R. Smart (eds.) it lists drugs and

environmental agents and one of the drugs listed is Pyridoxine (vitamin

B6). The article states this list is a list of neurotoxic agents that

causes neuropathy. My question is this:

Why is Pyridoxine (vitamin B6) in everything we drink or eat if it

causes neuropathy and is a neurotoxin?

Dana

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This is from Wikipedia: Please note that the RDA for people varies between

1.3 and 1.7 mg/day. Two ounces of canned tuna provides about 0.2 mg, if I

remember right. You would really have something wrong with you to need

anything over say, 20 mg/day. But it is certainly good of you to question at

what levels supplements can cause toxicity. I would never take say, huge

doseages of vitamin C for example. Biff Byrum

" " None of the studies, in which an objective neurological examination was

performed, found evidence of sensory nerve damage at intakes of pyridoxine

below 200 mg/day. In order to prevent sensory neuropathy in virtually all

individuals, the Food and Nutrition Board of the Institute of Medicine set

the tolerable upper intake level (UL) for pyridoxine at 100 mg/day for

adults. Because placebo-controlled studies have generally failed to show

therapeutic benefits of high doses of pyridoxine, there is little reason to

exceed the UL of 100 mg/day. Studies have shown, however, that in the case

of individuals diagnosed with autism, high doses of vitamin B6 given with

magnesium have been found to be extremely beneficial. " "

[] Vitamin B6: Neurotoxicology

> In table 1 from the article Biochemical and Molecular Neurotoxicology

> (chapter 18 & 19); Introduction to Biochemical Toxicology (third

> edition, 2000) E. Hodgson and R. Smart (eds.) it lists drugs and

> environmental agents and one of the drugs listed is Pyridoxine (vitamin

> B6). The article states this list is a list of neurotoxic agents that

> causes neuropathy. My question is this:

>

> Why is Pyridoxine (vitamin B6) in everything we drink or eat if it

> causes neuropathy and is a neurotoxin?

>

> Dana

>

>

>

> FAIR USE NOTICE:

>

>

>

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Are you all aware that the information in Wikipedia can be edited by you, me or

anyone else? Just thought I would let you know that.

Biff Byrum <bbyrum9@...> wrote: This is from Wikipedia: Please

note that the RDA for people varies between

1.3 and 1.7 mg/day. Two ounces of canned tuna provides about 0.2 mg, if I

remember right. You would really have something wrong with you to need

anything over say, 20 mg/day. But it is certainly good of you to question at

what levels supplements can cause toxicity. I would never take say, huge

doseages of vitamin C for example. Biff Byrum

" " None of the studies, in which an objective neurological examination was

performed, found evidence of sensory nerve damage at intakes of pyridoxine

below 200 mg/day. In order to prevent sensory neuropathy in virtually all

individuals, the Food and Nutrition Board of the Institute of Medicine set

the tolerable upper intake level (UL) for pyridoxine at 100 mg/day for

adults. Because placebo-controlled studies have generally failed to show

therapeutic benefits of high doses of pyridoxine, there is little reason to

exceed the UL of 100 mg/day. Studies have shown, however, that in the case

of individuals diagnosed with autism, high doses of vitamin B6 given with

magnesium have been found to be extremely beneficial. " "

[] Vitamin B6: Neurotoxicology

> In table 1 from the article Biochemical and Molecular Neurotoxicology

> (chapter 18 & 19); Introduction to Biochemical Toxicology (third

> edition, 2000) E. Hodgson and R. Smart (eds.) it lists drugs and

> environmental agents and one of the drugs listed is Pyridoxine (vitamin

> B6). The article states this list is a list of neurotoxic agents that

> causes neuropathy. My question is this:

>

> Why is Pyridoxine (vitamin B6) in everything we drink or eat if it

> causes neuropathy and is a neurotoxin?

>

> Dana

>

>

>

> FAIR USE NOTICE:

>

>

>

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Well, gee, if you think Wiki was the first and only place I looked, you're

dead wrong. It was more like the fifth, it just had the least number of

six-bit words.

I don't use Wiki for everything, as I do recognize its limitations. But in

my favorite hobby of railroad research, I find them to be almost absolutely

correct and thorough gaoing back to the developement of the diesel

locomotive before WW 2. And I personally know the person who wrote the Wiki

article on the Zodiac Killer. I may not agree with all his ideas, but I

guarantee that he knows what he's talking about. To each his own. biff

Byrum

[] Vitamin B6: Neurotoxicology

>

> In table 1 from the article Biochemical and Molecular Neurotoxicology

> (chapter 18 & 19); Introduction to Biochemical Toxicology (third edition,

> 2000) E. Hodgson and R. Smart (eds.) it lists drugs and environmental

> agents and one of the drugs listed is Pyridoxine (vitamin B6). The article

> states this list is a list of neurotoxic agents that causes neuropathy. My

> question is this:

>>

>> Why is Pyridoxine (vitamin B6) in everything we drink or eat if it causes

>> neuropathy and is a neurotoxin?

>>

>> Dana

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Byrum, I apologize. I didn't mean anything about what you had said being wrong.

I was just talking about the sight itself. The owner has even said he was making

some changes to help keep the content factualy correct. But ya, I wasn't talking

about the content of your information being incorect. My bad.

Biff Byrum <bbyrum9@...> wrote: Well, gee, if you think Wiki

was the first and only place I looked, you're

dead wrong. It was more like the fifth, it just had the least number of

six-bit words.

I don't use Wiki for everything, as I do recognize its limitations. But in

my favorite hobby of railroad research, I find them to be almost absolutely

correct and thorough gaoing back to the developement of the diesel

locomotive before WW 2. And I personally know the person who wrote the Wiki

article on the Zodiac Killer. I may not agree with all his ideas, but I

guarantee that he knows what he's talking about. To each his own. biff

Byrum

[] Vitamin B6: Neurotoxicology

>

> In table 1 from the article Biochemical and Molecular Neurotoxicology

> (chapter 18 & 19); Introduction to Biochemical Toxicology (third edition,

> 2000) E. Hodgson and R. Smart (eds.) it lists drugs and environmental

> agents and one of the drugs listed is Pyridoxine (vitamin B6). The article

> states this list is a list of neurotoxic agents that causes neuropathy. My

> question is this:

>>

>> Why is Pyridoxine (vitamin B6) in everything we drink or eat if it causes

>> neuropathy and is a neurotoxin?

>>

>> Dana

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