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so ok i read it 3 or 4 times , this one is fun :-) the older you get , the

wiser !

sarah , crone of paradise

National Library of Medicine: IGM Full Record Screen

TITLE: Somatosensory evoked potentials to median nerve stimulation in

meningomyelocele: what is occurring in the hindbrain and its connections

during growth?AUTHORS: Nishimura T; Mori KAUTHOR AFFILIATION: Department

of Neurosurgery, Taiju-Kai Foundation, Kagawa Prefecture, Japan.SOURCE:

Childs Nerv Syst 1996 Jan;12(1):13-26CITATION IDS: PMID: 8869170 UI:

97022810ABSTRACT: Twenty patients with meningomyelocele (MMC) and

shunted hydrocephalus, ranging in age from 3 to 23 years old, underwent

serial recording of short-latency somatosensory evoked potentials (SEPs)

to median nerve stimulation, on the basis of which to assess the

evolution of dysfunction in the brainstem and its connections (cervical

spinal cord, cervical nerve roots, lower cranial nerves). Eighteen

patients had Chiari type II malformations, none of which was

symptomatic. In all 20 patients, serial SEP recordings were obtained

repeatedly after periods ranging from 2 to 7 years. The results were as

follows: (1) the ratio of EP-N13 interpeak latencies (IPLs) to body

height (BH) tended to lengthen gradually after starting in the normal

range with growth. (2) In contrast, the ratio N13-N20 IPLs/BH decreased

continuously to the normal range with growth, after initial

prolongation. These findings and our earlier studies of brainstem

auditory evoked potentials suggest that compression and traction result

in strangulation of the cervical spinal cord and kinked medulla as well

as stretching of the cervical nerve roots and lower cranial nerves.

However, primary intrinsic functional disorders of the brainstem

appeared to improve gradually during growth. The natural history of

Chiari type II malformations involves these opposing dynamic phenomena

in the hindbrain and its connections.MAIN MESH HEADINGS: *Evoked

Potentials, Somatosensory

Median Nerve/*physiopathology

Meningomyelocele/*physiopathology

Rhombencephalon/*physiopathology ADDITIONAL MESH HEADINGS: Adolescence

Adult

Aging/physiology

Child

Child, Preschool

Electric Stimulation

Female

Human

Magnetic Resonance Imaging

Male

Meningomyelocele/diagnosis

Neural Pathways/physiopathology PUBLICATION TYPES: JOURNAL ARTICLE

REVIEW

REVIEW, TUTORIAL LANGUAGES: Eng

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