Mucocutaneous Candidiasis Facts and Mucocutaneous Candidiasis Treatment

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Mucocutaneous Candidiasis Facts and Mucocutaneous Candidiasis

Treatment

December 15, 2007

American Chronicle - Beverly Hills,CA*

Ricky Hussey

http://www.americanchronicle.com/articles/viewArticle.asp?

articleID=46010

Chronic mucocutaneous candidiasis is a hereditary immunodeficiency

disorder in which T lymphocytes malfunction. Mucocutaneous

candidiasis affects males and females alike and usually develops in

childhood. MC usually manifests in infancy or early childhood (60-

80% of cases), with a mean age of onset of 3 years. Delayed or adult

onset of the disease is reported and can be associated with thymoma,

myasthenia gravis, and bone marrow abnormalities. Mucocutaneous

candidiasis is also known as Candida related complex. It affects

males and females equally. Chronic mucocutaneous candidiasis occur

in childhood, there are a number of cases that first appear in

adulthood, sometimes as late as 50 years of age.

Causes

CMC occurs in a heterogeneous group of patients with a wide spectrum

of immune dysregulation, ranging from Candida-specific decreased

immunity to a broader immune defect.

Symptoms

# Oral Thrush -- mouth, tongue, and throat are covered with a

cream/white-colored, curdlike film (plaques or lesions) or even

ulcers (open areas)

# Thrush lesions may also be seen in the esophagus (the tube that

connects the mouth to the stomach), causing pain and difficulty

swallowing.

# Candida can also form lesions on the larynx (vocal cord), causing

hoarse voice.

Diagnosis

The diagnosis of chronic mucocutaneous candidiasis, is made on

clinical grounds. Microscopy and culture of skin swabs and scrapings

confirm the presence of organisms.

Mucocutaneous Candidiasis Treatment

Most patients with chronic mucocutaneous candidiasis are treated

with chronic antibiotics that are specific for fungal infections.

Patients should be evaluated periodically for endocrine disorders

and those endocrine disorders should be treated as necessary.

# The standard treatment consists of anti-fungal medication

(prescription).

# Before starting medication, it is good idea for women to make sure

that they are not pregnant.

# Clotrimazole troches (candy) or Nystatin solution is helpful in

oral Thrush.

Summary of Mucocutaneous Candidiasis

This condition mainly attacks young children although it has been

recorded in a few adults patients. Almost any part of your body can

be attacked by this skin disease and you have to be aware at all

times.