sorry, I'm just not finding any excuses

[Guest guest]

for a any doctor who cares about saving lives, not to do any testing

for fungal infections when someone says they have been exposed to

molds.

pulmonary fungal infection.

(colonization and infection)

nwws for early diagnoses and prompt antifungal therapy

http://www.chestjournal.org/cgi/content/full/120/1/177

------------------------------

this is mostly about newbirns but informative about colonization and

systemic fungal infections that follow it. AND NEED OF IMMEDITE

TREATMENT!

neonate,immunicompromized patients-prophylacticfluconazole-

progression from initial colonization to massive colonization to

systemic infection. ?

defination of systemic fungal infection(SFI)-defoned a positive

culture(1)from blood(drawn from peripheral sites)or(2)from

urine,sterile bladder catheterization(with growth of 10,000fungal

organisms ml.)or(3)from CSF or (4)

frpm inteavacular catheter tip(only if.....previous document

SFI.......

diagnostic implemented guidelines

treatment,identifacation from cultures...

analysis showed an assc. between occurance of SFI and colonization.

fluconazile reduced or prevented proggression to infection in more

than half of colonized neonates.

most effective in reduceing or preventing proggression from

colonization to infection.

discusion- fluconazole wanes beyond a certain intencity of

colonization, showing need for starting treatment early, not waiting

until colonization is detected. studies show a

reduction of morbidity and mortalitly,both adults and infants

in this strategy of early preventive

practice.

http://pediatrics.aappublications.org/cgi/content/full/117/1/e22